Blockade of interleukin 6 by rat anti-mouse interleukin 6 receptor antibody promotes fracture healing
暂无分享,去创建一个
Wentao Zhang | Yang Liu | J. Fan | Tao Song | Lei Huang | Shaojiang Liu
[1] Guanghui Liu,et al. TNF-α is upregulated in T2DM patients with fracture and promotes the apoptosis of osteoblast cells in vitro in the presence of high glucose. , 2016, Cytokine.
[2] S. Papapoulos,et al. Modulating Bone Resorption and Bone Formation in Opposite Directions in the Treatment of Postmenopausal Osteoporosis , 2015, Drugs.
[3] M. Suzuki,et al. THU0061 The Effect of Anti-IL-6 Receptor Antibody on Cartilage Destruction in a Mouse Model of Collagen-Induced Arthritis , 2015 .
[4] M. Amling,et al. Midkine-Deficiency Delays Chondrogenesis during the Early Phase of Fracture Healing in Mice , 2014, PloS one.
[5] Y. Ohira,et al. Anti-interleukin-6 receptor antibody (MR16-1) promotes muscle regeneration via modulation of gene expressions in infiltrated macrophages. , 2014, Biochimica et biophysica acta.
[6] S. Achilefu,et al. Intravenous Application of CD271-selected Mesenchymal Stem Cells During Fracture Healing , 2014, Journal of orthopaedic trauma.
[7] M. Betsch,et al. The early phase influence of bone marrow concentrate on metaphyseal bone healing. , 2013, Injury.
[8] P. Tak,et al. Absence of Fms-like tyrosine kinase 3 ligand (Flt3L) signalling protects against collagen-induced arthritis , 2013, Annals of the rheumatic diseases.
[9] J. Cauley,et al. Public health impact of osteoporosis. , 2013, The journals of gerontology. Series A, Biological sciences and medical sciences.
[10] Kylie A Alexander,et al. Unraveling macrophage contributions to bone repair. , 2013, BoneKEy reports.
[11] H. Im,et al. Chondrocyte BMP2 signaling plays an essential role in bone fracture healing. , 2013, Gene.
[12] C. Irvin,et al. Role of IL-6 in Asthma and Other Inflammatory Pulmonary Diseases , 2012, International journal of biological sciences.
[13] H. Aro,et al. Different profiles of circulating sclerostin, IL-6 and TNF-alpha after hip fracture , 2012 .
[14] S. Cummings,et al. Rapidly increasing rates of hip fracture in Beijing, China , 2012, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.
[15] T. Cooney,et al. Effects of Interleukin‐6 Ablation on Fracture Healing in Mice , 2011, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.
[16] Jian-zheng Zhang,et al. Plasma concentrations of pro- and anti-inflammatory cytokines and outcome prediction in elderly hip fracture patients. , 2011, Injury.
[17] D. Tweardy,et al. IL-6-Mediated Activation of Stat3α Prevents Trauma/Hemorrhagic Shock-Induced Liver Inflammation , 2011, PloS one.
[18] L. Koenderman,et al. Systemic inflammation and fracture healing , 2011, Journal of leukocyte biology.
[19] A. Kimura,et al. IL‐6: Regulator of Treg/Th17 balance , 2010, European journal of immunology.
[20] G. Duda,et al. The early fracture hematoma and its potential role in fracture healing. , 2010, Tissue engineering. Part B, Reviews.
[21] L. Gibson,et al. Neurotrophins Regulate Bone Marrow Stromal Cell IL-6 Expression through the MAPK Pathway. , 2009, ATS 2009.
[22] C. Bäckesjö,et al. IL-6 receptor expression and IL-6 effects change during osteoblast differentiation. , 2008, Cytokine.
[23] C. Kaps,et al. Key regulatory molecules of cartilage destruction in rheumatoid arthritis: an in vitro study , 2008, Arthritis research & therapy.
[24] N. Pleshko Camacho,et al. Callus mineralization and maturation are delayed during fracture healing in interleukin-6 knockout mice. , 2007, Bone.
[25] R. Kurzrock,et al. Interleukin‐6 and its receptor in cancer , 2007, Cancer.
[26] M. Scherer,et al. Roles of neutrophil‐mediated inflammatory response in the bony repair of injured growth plate cartilage in young rats , 2006, Journal of leukocyte biology.
[27] M. Gardner,et al. Osteoporosis and Skeletal Fractures , 2006, HSS Journal.
[28] Kozo Nakamura,et al. Involvement of Endogenous Bone Morphogenetic Protein (BMP) 2 and BMP6 in Bone Formation* , 2005, Journal of Biological Chemistry.
[29] R. Iorio,et al. Total Hip Arthroplasty: Optimal Treatment for Displaced Femoral Neck Fractures in Elderly Patients , 2004, Clinical orthopaedics and related research.
[30] N. Fazzalari,et al. Increased expression of IL-6 and RANK mRNA in human trabecular bone from fragility fracture of the femoral neck. , 2004, Bone.
[31] Thomas A Einhorn,et al. Fracture healing as a post‐natal developmental process: Molecular, spatial, and temporal aspects of its regulation , 2003, Journal of cellular biochemistry.
[32] R. Price,et al. Therapeutic benefit of blocking interleukin-6 activity with an anti-interleukin-6 receptor monoclonal antibody in rheumatoid arthritis: a randomized, double-blind, placebo-controlled, dose-escalation trial. , 2002, Arthritis and rheumatism.
[33] Thomas D. Schmittgen,et al. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. , 2001, Methods.
[34] A. McMahon,et al. Indian hedgehog couples chondrogenesis to osteogenesis in endochondral bone development. , 2001, The Journal of clinical investigation.
[35] T. Kishimoto,et al. Interleukin-6 and its receptor in autoimmunity. , 1992, Journal of autoimmunity.
[36] N. Rozen,et al. Role of bone regeneration and turnover modulators in control of fracture. , 2007, Critical reviews in eukaryotic gene expression.
[37] A. Levine,et al. The role of the interleukin-6/gp130 signaling pathway in bone metabolism. , 2006, Vitamins and hormones.
[38] A. Aho. Electron microscopic and histological observations on fracture repair in young and old rats. , 1966, Acta pathologica et microbiologica Scandinavica.
[39] Aho Aj. Electron microscopic and histological observations on fracture repair in young and old rats. , 1966 .