The structure of amphotericin A. I. Mass spectrometric analysis of dodecahydroamphotericin A.

Amphotericin A had been transformed into dodecahydroamphotericin A by hydrogenation. Subsequently, the product obtained was reduced with metal borohydrides or borodeuterides and derivatized to volatile compounds which were analyzed by mass spectrometry.

[1]  P. Sidebottom,et al.  The proton magnetic resonance spectrum of amphotericin B , 1981 .

[2]  D. Doddrell,et al.  Assignment of proton-decoupled carbon-13 spectra of complex molecules by using polarization transfer spectroscopy. A superior method to off-resonance decoupling , 1980 .

[3]  E. Borowski,et al.  The structure of lienomycin, a pentaene macrolide antitumor antibiotic. I. The structure of the carbon skeleton and the location of functionalities. , 1980, The Journal of antibiotics.

[4]  E. Borowski,et al.  The structure of lienomycin, a pentaene macrolide antitumor antibiotic. II. The location of the pentaene chromophore and of six isolated double bonds. The complete structure of the antibiotic. , 1980, The Journal of antibiotics.

[5]  C. Schaffner,et al.  Structure and absolute configuration of the polyene macrolide antibiotic amphotericin B , 1970 .

[6]  E. Borowski,et al.  Chemical studies with amphotericin B. 3. The complete structure of the antibiotic. , 1970, Tetrahedron letters.

[7]  O. S. Chizhov,et al.  Mass spectrometry of hexosamines , 1966 .

[8]  K. M. Brobst,et al.  Determination of some components in corn syrup by gas-liquid chromatography of the trimethylsilyl derivatives. , 1966 .

[9]  W. Oroshnik,et al.  THE POLYENE ANTIFUNGAL ANTIBIOTICS. , 1963, Fortschritte der Chemie organischer Naturstoffe = Progress in the chemistry of organic natural products. Progres dans la chimie des substances organiques naturelles.

[10]  J. Vandeputte,et al.  Amphotericins A and B, antifungal antibiotics produced by a streptomycete. II. The isolation and properties of the crystalline amphotericins. , 1955, Antibiotics annual.