Does it have to be this complicated? Focus on "Single-column thalamocortical network model exhibiting gamma oscillations, spindles, and epileptogenic bursts".

In this issue, Traub et al. [2005][1] (p. 2194–2232) have given us a model of a single thalamocortical column. It has 3,560 cells of at least eight types, with up to dozens of compartments, each with many different intrinsic currents. Synapses include AMPA, N -methyl-d-aspartate (NMDA), and GABA