Quantitation of circulating peripheral blood plasma cells and their relationship to disease activity in patients with multiple myeloma

Background. The analysis of peripheral blood mononuclear cells for plasma cells and B‐cell surface light chain ratios may provide additional insight on the pathogenesis of multiple myeloma and predict disease activity. The goals of this study were to correlate these parameters with clinically determined disease activity and establish a cutoff value of circulating plasma cells that could be used in future clinical trials.

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