Identification of a new uracil-DNA glycosylase family by expression cloning using synthetic inhibitors

[1]  I. Hickson.  Base Excision Repair of DNA Damage , 1999 .

[2]  P. Lijnzaad,et al.  A physical map of 30,000 human genes. , 1998, Science.

[3]  L. Samson,et al.  Crystal Structure of a Human Alkylbase-DNA Repair Enzyme Complexed to DNA Mechanisms for Nucleotide Flipping and Base Excision , 1998, Cell.

[4]  L. Zon,et al.  Cloning of Mix-related homeodomain proteins using fast retrieval of gel shift activities, (FROGS), a technique for the isolation of DNA-binding proteins. , 1998, Proceedings of the National Academy of Sciences of the United States of America.

[5]  T. Waters,et al.  Kinetics of the Action of Thymine DNA Glycosylase* , 1998, The Journal of Biological Chemistry.

[6]  M. Saparbaev,et al.  3,N4-ethenocytosine, a highly mutagenic adduct, is a primary substrate for Escherichia coli double-stranded uracil-DNA glycosylase and human mismatch-specific thymine-DNA glycosylase. , 1998, Proceedings of the National Academy of Sciences of the United States of America.

[7]  P. Baumann,et al.  Role of the human RAD51 protein in homologous recombination and double-stranded-break repair. , 1998, Trends in biochemical sciences.

[8]  M. Kirschner,et al.  Geminin, an Inhibitor of DNA Replication, Is Degraded during Mitosis , 1998, Cell.

[9]  S. Biade,et al.  Involvement of Flap Endonuclease 1 in Base Excision DNA Repair* , 1998, The Journal of Biological Chemistry.

[10]  G. Verdine,et al.  Specific Binding of a Designed Pyrrolidine Abasic Site Analog to Multiple DNA Glycosylases* , 1998, The Journal of Biological Chemistry.

[11]  D. Bogenhagen,et al.  Efficient Repair of Abasic Sites in DNA by Mitochondrial Enzymes , 1998, Molecular and Cellular Biology.

[12]  L. Pearl,et al.  Crystal Structure of a G:T/U Mismatch-Specific DNA Glycosylase Mismatch Recognition by Complementary-Strand Interactions , 1998, Cell.

[13]  G. Verdine,et al.  Chemical approaches toward understanding base excision DNA repair. , 1997, Current opinion in chemical biology.

[14]  M. Kirschner,et al.  Specific Proteolysis of the Kinase Protein Kinase C-related Kinase 2 by Caspase-3 during Apoptosis , 1997, The Journal of Biological Chemistry.

[15]  Jay X. Tang,et al.  Caspase-3-generated fragment of gelsolin: effector of morphological change in apoptosis. , 1997, Science.

[16]  William Arbuthnot Sir Lane,et al.  The critical active-site amine of the human 8-oxoguanine DNA glycosylase, hOgg1: direct identification, ablation and chemical reconstitution. , 1997, Chemistry & biology.

[17]  F. Skorpen,et al.  Nuclear and mitochondrial uracil-DNA glycosylases are generated by alternative splicing and transcription from different positions in the UNG gene. , 1997, Nucleic acids research.

[18]  J. Essigmann,et al.  Kinetics of oxidized cytosine repair by endonuclease III of Escherichia coli. , 1997, Biochemistry.

[19]  H. Krokan,et al.  DNA glycosylases in the base excision repair of DNA. , 1997, The Biochemical journal.

[20]  I. Nicholl,et al.  Reconstitution of human base excision repair with purified proteins. , 1997, Biochemistry.

[21]  T. Lindahl,et al.  Second pathway for completion of human DNA base excision‐repair: reconstitution with purified proteins and requirement for DNase IV (FEN1) , 1997, The EMBO journal.

[22]  G. Verdine,et al.  A mammalian DNA repair enzyme that excises oxidatively damaged guanines maps to a locus frequently lost in lung cancer , 1997, Current Biology.

[23]  M. Kirschner,et al.  Systematic identification of mitotic phosphoproteins , 1997, Current Biology.

[24]  S. Benichou,et al.  A Sequence in the N-terminal Region of Human Uracil-DNA Glycosylase with Homology to XPA Interacts with the C-terminal Part of the 34-kDa Subunit of Replication Protein A* , 1997, The Journal of Biological Chemistry.

[25]  C. Iden,et al.  NH2-terminal Proline Acts as a Nucleophile in the Glycosylase/AP-Lyase Reaction Catalyzed by Escherichia coli Formamidopyrimidine-DNA Glycosylase (Fpg) Protein* , 1997, The Journal of Biological Chemistry.

[26]  D. Barnes,et al.  Reconstitution of DNA base excision‐repair with purified human proteins: interaction between DNA polymerase beta and the XRCC1 protein. , 1996, The EMBO journal.

[27]  D. Sarracino,et al.  Quantitative MALDI-TOF MS of oligonucleotides and a nuclease assay , 1996 .

[28]  P. Deloukas,et al.  A Gene Map of the Human Genome , 1996, Science.

[29]  J. Jiricny,et al.  Base analog and neighboring base effects on substrate specificity of recombinant human G:T mismatch-specific thymine DNA-glycosylase. , 1996, Biochemistry.

[30]  G. Verdine,et al.  Structural Basis for the Excision Repair of Alkylation-Damaged DNA , 1996, Cell.

[31]  A. Sancar.  No "End of History" for Photolyases , 1996, Science.

[32]  C. Auffray,et al.  The I.M.A.G.E. Consortium: an integrated molecular analysis of genomes and their expression. , 1996, Genomics.

[33]  R. Ladner,et al.  Affinity purification and comparative analysis of two distinct human uracil-DNA glycosylases. , 1996, Experimental cell research.

[34]  L. Pearl,et al.  The structural basis of specific base-excision repair by uracil–DNA glycosylase , 1996, Nature.

[35]  R. Fleischmann,et al.  The Minimal Gene Complement of Mycoplasma genitalium , 1995, Science.

[36]  R. Fleischmann,et al.  Initial assessment of human gene diversity and expression patterns based upon 83 million nucleotides of cDNA sequence. , 1995, Nature.

[37]  R. Lloyd,et al.  Studies on the Catalytic Mechanism of Five DNA Glycosylases , 1995, The Journal of Biological Chemistry.

[38]  Y. Matsumoto,et al.  Excision of deoxyribose phosphate residues by DNA polymerase beta during DNA repair. , 1995, Science.

[39]  M. Kirschner,et al.  Use of an oocyte expression assay to reconstitute inductive signaling. , 1995, Proceedings of the National Academy of Sciences of the United States of America.

[40]  A. Ganesan,et al.  Specific binding of the DNA repair enzyme AlkA to a pyrrolidine-based inhibitor , 1995 .

[41]  H. Krokan,et al.  Properties of a recombinant human uracil-DNA glycosylase from the UNG gene and evidence that UNG encodes the major uracil-DNA glycosylase. , 1995, Biochemistry.

[42]  S. Mitra,et al.  Purification and biochemical characterization of recombinant N-methylpurine-DNA glycosylase of the mouse. , 1994, Biochemistry.

[43]  G. Verdine,et al.  The effects of N7-methylguanine on duplex DNA structure. , 1994, Chemistry & biology.

[44]  Yoshihiro,et al.  Proliferating cell nuclear antigen-dependent abasic site repair in Xenopus laevis oocytes: an alternative pathway of base excision DNA repair. , 1994, Molecular and cellular biology.

[45]  H. Weintraub,et al.  Expression of achaete-scute homolog 3 in Xenopus embryos converts ectodermal cells to a neural fate. , 1994, Genes & development.

[46]  I. Antoshechkin,et al.  Substrate specificity of Fpg protein. Recognition and cleavage of oxidatively damaged DNA. , 1994, The Journal of biological chemistry.

[47]  S. Srivastava,et al.  1,N6-etheno deoxy and ribo adenosine and 3,N4-etheno deoxy and ribo cytidine phosphoramidites. Strongly fluorescent structures for selective introduction in defined sequence DNA and RNA molecules. , 1994, Nucleic acids research.

[48]  T. O'Connor,et al.  Purification and characterization of human 3-methyladenine-DNA glycosylase. , 1993, Nucleic acids research.

[49]  P. Bolton,et al.  Characterization of the effects of a thymine glycol residue on the structure, dynamics, and stability of duplex DNA by NMR. , 1993, The Journal of biological chemistry.

[50]  T. Lindahl.  Instability and decay of the primary structure of DNA , 1993, Nature.

[51]  H. Krokan,et al.  Cell cycle regulation and in vitro hybrid arrest analysis of the major human uracil-DNA glycosylase. , 1991, Nucleic acids research.

[52]  K Meyer-Siegler,et al.  A human nuclear uracil DNA glycosylase is the 37-kDa subunit of glyceraldehyde-3-phosphate dehydrogenase. , 1991, Proceedings of the National Academy of Sciences of the United States of America.

[53]  G. A. van der Marel,et al.  Solid-phase synthesis of DNA fragments containing the modified base 7-hydro-8-oxo-2'-deoxyguanosine. , 1991, Nucleic acids research.

[54]  C. Iden,et al.  An Improved Method for The Preparation Of The Phosphoramidites Of Modified 2′-Deoxynucleotides: Incorporation Of 8-Oxo-2′-Deoxy-7H-Guanosine Into Synthetic Oligomers , 1991 .

[55]  T. Kunkel,et al.  A sensitive genetic assay for the detection of cytosine deamination: determination of rate constants and the activation energy. , 1990, Biochemistry.

[56]  R. Teoule,et al.  Synthesis and Characterization of DNA Fragments Bearing an Adenine Radiation Product: 7,8‐Dihydroadenin‐8‐one , 1988 .

[57]  A. Grollman,et al.  Oligodeoxynucleotides containing synthetic abasic sites. Model substrates for DNA polymerases and apurinic/apyrimidinic endonucleases. , 1987, The Journal of biological chemistry.

[58]  B Nyberg,et al.  Heat-induced deamination of cytosine residues in deoxyribonucleic acid. , 1974, Biochemistry.

[59]  L. Zon,et al.  Small pool expression screening: identification of genes involved in cell cycle control, apoptosis, and early development. , 1997, Methods in enzymology.

[60]  R. Cunningham,et al.  DNA glycosylases. , 1997, Mutation research.

[61]  P. Modrich,et al.  Mismatch repair in replication fidelity, genetic recombination, and cancer biology. , 1996, Annual review of biochemistry.

[62]  R. Wood.  DNA repair in eukaryotes. , 1996, Annual review of biochemistry.

[63]  A. Sancar.  DNA excision repair. , 1996, Annual review of biochemistry.

[64]  Y. Nakabeppu,et al.  Regulation and expression of the adaptive response to alkylating agents. , 1988, Annual review of biochemistry.