Comparison of spectral domain optical coherence tomography and color photographic imaging of the optic nerve head in management of glaucoma.

BACKGROUND AND OBJECTIVE Spectral domain optical coherence tomography (SD-OCT) allows three-dimensional imaging of the optic disc. The objective of this study was to compare optic disc and cup margins between fundus photographs and SD-OCT. PATIENTS AND METHODS Eighteen eyes with glaucoma were examined by a custom-built SD-OCT OCT fundus images were used to register fundus photographs and SD-OCT volume. RESULTS Disc margins on fundus photographs corresponded to termination of the highly reflective straight line that represented the retinal pigment epithelium (RPE) or the highly reflective curved line that connected to the RPE on the OCT B-scan images at 99.3% of the positions along the disc edges. Cup margins on fundus photographs corresponded at 73.6% of the positions to the interior border of the hyporeflective regions on the OCT fundus images. CONCLUSIONS Excellent to fair correspondence in the determination of disc and cup margins between fundus photographs and SD-OCT images was shown.

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