Adenovirus-Mediated Coexpression of DCX and SPARC Radiosensitizes Human Malignant Glioma Cells

[1]  L. Poisson,et al.  PTEN suppresses SPARC-induced pMAPKAPK2 and inhibits SPARC-induced Ser78 HSP27 phosphorylation in glioma. , 2013, Neuro-oncology.

[2]  M. Jankowski,et al.  Deletion of the SPARC acidic domain or EGF-like module reduces SPARC-induced migration and signaling through p38 MAPK/HSP27 in glioma. , 2012, Carcinogenesis.

[3]  A. Ashworth,et al.  The DNA damage response and cancer therapy , 2012, Nature.

[4]  Xin Jiang,et al.  Knockdown of secreted protein acidic and rich in cysteine (SPARC) expression diminishes radiosensitivity of glioma cells. , 2011, Cancer biotherapy & radiopharmaceuticals.

[5]  J. Xiang,et al.  Synergistic tumor suppression by adenovirus-mediated inhibitor of growth 4 and interleukin-24 gene cotransfer in hepatocarcinoma cells. , 2011, Cancer biotherapy & radiopharmaceuticals.

[6]  Erwin G. Van Meir,et al.  Exciting New Advances in Neuro‐Oncology: The Avenue to a Cure for Malignant Glioma , 2010, CA: a cancer journal for clinicians.

[7]  M. Chopp,et al.  Single doublecortin gene therapy significantly reduces glioma tumor volume , 2010, Journal of neuroscience research.

[8]  M. Chopp,et al.  Doublecortin induces mitotic microtubule catastrophe and inhibits glioma cell invasion , 2009, Journal of neurochemistry.

[9]  A. Raz,et al.  SPARC upregulates MT1-MMP expression, MMP-2 activation, and the secretion and cleavage of galectin-3 in U87MG glioma cells , 2007, Neuroscience Letters.

[10]  M. Chopp,et al.  Ectopic doublecortin gene expression suppresses the malignant phenotype in glioblastoma cells. , 2006, Cancer research.

[11]  M. West,et al.  Gene expression profiling and genetic markers in glioblastoma survival. , 2005, Cancer research.

[12]  T. Pawlik,et al.  Role of cell cycle in mediating sensitivity to radiotherapy. , 2004, International journal of radiation oncology, biology, physics.

[13]  S. Rempel,et al.  cDNA Array Analysis of SPARC-modulated Changes in Glioma Gene Expression , 2002, Journal of Neuro-Oncology.

[14]  N. Lemke,et al.  Secreted protein acidic and rich in cysteine promotes glioma invasion and delays tumor growth in vivo. , 2002, Cancer research.

[15]  C. Walsh,et al.  Neuronal migration disorders: from genetic diseases to developmental mechanisms , 2000, Trends in Neurosciences.

[16]  Liu Fenju Effects of DCX and SPARC co-expression on the apoptosis of human glioma cells U-87MG induced by X-rays irradiation , 2013 .

[17]  R. Brekken,et al.  SPARC, a matricellular protein: at the crossroads of cell-matrix communication. , 2001, Matrix biology : journal of the International Society for Matrix Biology.