Night-shift work and cardiovascular risk among employees of a public university.

OBJECTIVE To estimate the association between night-shift work and high cardiovascular risk. METHODS Cross-sectional study carried out with 211 workers of both genders, aged between 30 and 64 years, working on the health campus of a public university in the state of Minas Gerais, Brazil. Night-shift work was defined as a work shift between 7 pm and 7 am, and high cardiovascular risk was calculated based on the Framingham score. The association between night-shift work and high cardiovascular risk was estimated by the prevalence ratio (PR) and its 95% confidence interval (95% CI) after adjusting for potential confounding factors, calculated by Poisson regression. RESULTS Night-shift work was performed by 38.4% of the individuals, and high cardiovascular risk was diagnosed in 28% of the sample. Hypertension was more prevalent among night-shift compared with day-shift workers (p < 0.05). In the bivariate analysis, night-shift work, passive and high job strain categories at the demand-control scale, work time > 120 months, schooling > 9 years, family income > 6 minimum wages, level 2 abdominal obesity, and triglyceride levels > 150 mg/dL were associated with high cardiovascular risk (p < 0.05). After multivariate analysis, night-shift work remained independently associated with high cardiovascular risk (PR = 1.67; 95% CI = 1.10-2.54). CONCLUSION The prevalence of high cardiovascular risk was 67% higher among night-shift workers. This association should be considered when discussing the promotion of workers' health regarding changes in the work process.

[1]  B. Duncan,et al.  [IV Brazilian Guideline for Dyslipidemia and Atherosclerosis prevention: Department of Atherosclerosis of Brazilian Society of Cardiology]. , 2007, Arquivos Brasileiros de Cardiologia.

[2]  N. Kawakami,et al.  The Job Content Questionnaire (JCQ): an instrument for internationally comparative assessments of psychosocial job characteristics. , 1998, Journal of occupational health psychology.

[3]  IJmert Kant,et al.  Smoking among Shift Workers: More Than a Confounding Factor , 2006, Chronobiology international.

[4]  A. Steptoe,et al.  Work-Related Psychosocial Factors and the Development of Ischemic Heart Disease: A Systematic Review , 2009, Cardiology in review.

[5]  Akinori Nakata,et al.  Health problems due to long working hours in Japan: working hours, workers' compensation (Karoshi), and preventive measures. , 2006, Industrial health.

[6]  C. Power,et al.  Shift work and risk factors for cardiovascular disease: a study at age 45 years in the 1958 British birth cohort , 2010, European Journal of Epidemiology.

[7]  K. Fiscella,et al.  Do changes in traditional coronary heart disease risk factors over time explain the association between socio-economic status and coronary heart disease? , 2011, BMC cardiovascular disorders.

[8]  Jong-Dar Chen,et al.  OBESITY AND HIGH BLOOD PRESSURE OF 12-HOUR NIGHT SHIFT FEMALE CLEAN-ROOM WORKERS , 2010, Chronobiology international.

[9]  Murilo Foppa,et al.  Impacto econômico dos casos de doença cardiovascular grave no Brasil: uma estimativa baseada em dados secundários , 2008 .

[10]  Michael Smolensky,et al.  Biological Clocks and Shift Work: Circadian Dysregulation and Potential Long-term Effects , 2006, Cancer Causes & Control.

[11]  H. Burr,et al.  A 12 year prospective study of circulatory disease among Danish shift workers , 2006, Occupational and Environmental Medicine.

[12]  B. Ainsworth,et al.  International physical activity questionnaire: 12-country reliability and validity. , 2003, Medicine and science in sports and exercise.

[13]  N. Unwin,et al.  Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III) Detection, Evaluation, and Treatment of High Blood Cholesterol Education Program (NCEP) Expert Panel on Executive Summary of the Third Report of the National , 2009 .

[14]  Dóra Chor,et al.  Versão resumida da "job stress scale": adaptação para o português , 2004 .

[15]  A. Knutsson,et al.  Health disorders of shift workers. , 2003, Occupational medicine.

[16]  T. Lohman,et al.  Anthropometric Standardization Reference Manual , 1988 .

[17]  C. O’Donnell,et al.  [Cardiovascular risk factors. Insights from Framingham Heart Study]. , 2008, Revista espanola de cardiologia.

[18]  K. Rexrode,et al.  American Journal of Epidemiology Original Contribution Rotating Night Shift Work and the Risk of Ischemic Stroke , 2022 .

[19]  A. Rodgers,et al.  Global burden of blood-pressure-related disease, 2001 , 2008, The Lancet.

[20]  G. Fialho,et al.  Effects of 24-h shift work in the emergency room on ambulatory blood pressure monitoring values of medical residents. , 2006, American journal of hypertension.

[21]  F. Raal,et al.  Shift work and its effects on the cardiovascular system , 2008, Cardiovascular journal of Africa.

[22]  T. Ebara,et al.  Effects of the length and timing of nighttime naps on task performance and physiological function. , 2004, Revista de saude publica.

[23]  P. Nicholson.  Shift work and chronic disease: the epidemiological evidence. , 2011, Occupational medicine.

[24]  F M Fischer,et al.  [Fatigue and workability in twelve-hour fixed shifts]. , 2001, Revista de saude publica.

[25]  James Carton.  Manual de patología clínica , 2013 .

[26]  David A Groneberg,et al.  The impact of shift work induced chronic circadian disruption on IL-6 and TNF-α immune responses , 2010, Journal of occupational medicine and toxicology.

[27]  Yoshihisa Fujino,et al.  A prospective cohort study of shift work and risk of ischemic heart disease in Japanese male workers. , 2006, American journal of epidemiology.

[28]  H. Bøggild,et al.  Shiftwork and Cardiovascular Disease: Review of Disease Mechanisms , 2000, Reviews on environmental health.

[29]  Sociedade Brasileira de Cardiologia-SBC,et al.  [V Brazilian Guidelines in Arterial Hypertension. ]. , 2007, Arquivos brasileiros de cardiologia.

[30]  T. Araújo,et al.  Estresse ocupacional e saúde: contribuições do Modelo Demanda-Controle , 2003 .

[31]  Deirdre McCann,et al.  Working Time Around the World: Trends in Working Hours, Laws, and Policies in a Global Comparative Perspective , 2007 .

[32]  J. Pilcher,et al.  Blood Pressure Increases During a Simulated Night Shift in Persons at Risk for Hypertension , 2010, International journal of behavioral medicine.

[33]  L. Santarelli,et al.  Assessment of cardiovascular risk in shift healthcare workers , 2008, European journal of cardiovascular prevention and rehabilitation : official journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology.

[34]  F. Fischer,et al.  The impact of night work on subjective reports of well-being: an exploratory study of health care workers from five nations. , 2004, Revista de saude publica.

[35]  S. Barreto,et al.  IV Diretriz Brasileira sobre Dislipidemias e Prevenção da Aterosclerose: Departamento de Aterosclerose da Sociedade Brasileira de Cardiologia , 2007 .

[36]  M. Tafil-Klawe,et al.  Daily changes in cardiac and vascular blood pressure components during breath holding episodes in obstructive sleep apnea patients after day-shift and night-shift work. , 2007, Journal of physiology and pharmacology : an official journal of the Polish Physiological Society.

[37]  Roberto Elosua,et al.  Factores de riesgo cardiovascular. Perspectivas derivadas del Framingham Heart Study , 2008 .