A Facile Synthesis of Phenyl 1-Benzyloxycarbonylamino Arylmethylphosphinopeptide Derivatives

Abstract With acetyl chloride as the solvent, benzyl carbamate reacted with aromatic aldehyde and dichlorophenylphosphine to give phenyl 1-aryl methylphosphinic chloride, which reacted with an amino acid ester to give corresponding phosphinopeptide derivatives.