Identification of the key parameters in a mathematical model of PAR1-mediated signaling in endothelial cells
暂无分享,去创建一个
[1] J. Blank,et al. Activation of cytosolic phosphoinositide phospholipase C by G-protein beta gamma subunits. , 1992, The Journal of biological chemistry.
[2] H. Hamm,et al. Mathematical model of PAR1-mediated activation of human platelets. , 2011, Molecular bioSystems.
[3] A. Gilman,et al. p115 RhoGEF, a GTPase activating protein for Gα12 and Gα13 , 1998 .
[4] Joseph A. C. Delaney. Sensitivity analysis , 2018, The African Continental Free Trade Area: Economic and Distributional Effects.
[5] Peter J Woolf,et al. A Spatial Focusing Model for G Protein Signals , 2003, The Journal of Biological Chemistry.
[6] Thomas S. Deisboeck,et al. Investigating Differential Dynamics of the MAPK Signaling Cascade Using a Multi-Parametric Global Sensitivity Analysis , 2009, PloS one.
[7] Kwang-Hyun Cho,et al. Experimental Design in Systems Biology, Based on Parameter Sensitivity Analysis Using a Monte Carlo Method: A Case Study for the TNFα-Mediated NF-κ B Signal Transduction Pathway , 2003, Simul..
[8] G. Hornberger,et al. Approach to the preliminary analysis of environmental systems , 1981 .
[9] H. Hamm,et al. Functional Selectivity of G Protein Signaling by Agonist Peptides and Thrombin for the Protease-activated Receptor-1*[boxs] , 2005, Journal of Biological Chemistry.
[10] S. Rittenhouse. Human platelets contain phospholipase C that hydrolyzes polyphosphoinositides. , 1983, Proceedings of the National Academy of Sciences of the United States of America.
[11] G. Lemon,et al. Metabotropic receptor activation, desensitization and sequestration-I: modelling calcium and inositol 1,4,5-trisphosphate dynamics following receptor activation. , 2003, Journal of theoretical biology.
[12] Y. Takai,et al. Purification and characterization of a GTP-binding protein with a molecular weight of 20,000 in bovine brain membranes. Identification as the rho gene product. , 1988, The Journal of biological chemistry.
[13] Kwang-Hyun Cho,et al. In silico identification of the key components and steps in IFN‐γ induced JAK‐STAT signaling pathway , 2005, FEBS letters.
[14] E M Ross,et al. Regulation of phospholipase C-beta1 by Gq and m1 muscarinic cholinergic receptor. Steady-state balance of receptor-mediated activation and GTPase-activating protein-promoted deactivation. , 1996, The Journal of biological chemistry.
[15] S. Coughlin,et al. Thrombin signalling and protease-activated receptors , 2000, Nature.
[16] K. Burridge,et al. Focal adhesions, contractility, and signaling. , 1996, Annual review of cell and developmental biology.
[17] J. Keizer,et al. A single-pool inositol 1,4,5-trisphosphate-receptor-based model for agonist-stimulated oscillations in Ca2+ concentration. , 1992, Proceedings of the National Academy of Sciences of the United States of America.
[18] E M Ross,et al. Rapid GTP binding and hydrolysis by G(q) promoted by receptor and GTPase-activating proteins. , 1999, Proceedings of the National Academy of Sciences of the United States of America.
[19] P Bisegna,et al. Mathematical model of the spatio-temporal dynamics of second messengers in visual transduction. , 2003, Biophysical journal.
[20] Manash S. Chatterjee,et al. A molecular signaling model of platelet phosphoinositide and calcium regulation during homeostasis and P2Y1 activation. , 2008, Blood.
[21] C. Foster,et al. Binding of a thrombin receptor tethered ligand analogue to human platelet thrombin receptor. , 1997, Molecular pharmacology.
[22] R. T. Miller,et al. Purification and characterization of the alpha subunit of G13. , 1994, The Journal of biological chemistry.
[23] E M Ross,et al. GTPase-activating proteins for heterotrimeric G proteins: regulators of G protein signaling (RGS) and RGS-like proteins. , 2000, Annual review of biochemistry.
[24] P.K. Dhar,et al. Computational approach to systems biology: from fraction to integration and beyond , 2004, IEEE Transactions on NanoBioscience.
[25] P Bisegna,et al. Dynamics of mouse rod phototransduction and its sensitivity to variation of key parameters. , 2010, IET systems biology.
[26] P C Sternweis,et al. p115 RhoGEF, a GTPase activating protein for Galpha12 and Galpha13. , 1998, Science.