Rear-end collisions are the most common type of car accidents. In this paper, the anti-rear-end collision warning device based on emergency braking behavior prediction was designed to reduce the occurrence of rear-end collision. Through analyzing drivers’ braking behaviors in the car-following process, the anti-rear-end collision method based on emergency braking behavior prediction was proposed. The emergency braking model was established based on the change rate of acceleration pedal’s and clutch pedal’s displacement. The anti-rear-end collision warning device consisting of the sensors on the pedals, capture card, IPC and emergency brake lamps was developed. The rear-end collision warning device was tested on the roads. The road test results show that the emergency brake lamps are lighted in advance about 0.1–0.3 s compared with the conventional brake lamps and warn the drivers to brake earlier. The device could reduce the incidence of rear-end collisions effectively and improve road safety.