Doğal Bir Antimikrobiyel: Oleuropein

Zeytin agacinin temel fenolik bilesigi olan oleuropein, zeytin meyvelerinin karakteristik aci tadindan sorumludur. Zeytinin yenilebilir ozellik kazanmasi icin mutlaka ortamdan uzaklastirilmasi gerekir. Elenolik asit ve hidroksitriosolun heterozidik esteri olan oleuropein, insan sagligi uzerinde bircok yararli etkiye sahiptir. Bircok arastirmaci tarafindan antimikrobiyel ozellige sahip oldugu ispat edilmis olan bu bilesik alternatif gida katkisi olarak da kullanilabilir. Bu derlemede, oleuropeinin kimyasal yapisi ve antimikrobiyel etkisine iliskin yapilan calismalardan soz edilmektedir

[1]  S. Lee-Huang,et al.  Oleuropein and Related Compounds Reduce Atherosclerosis , 2010 .

[2]  O. Lee,et al.  Antioxidant and antimicrobial activities of individual and combined phenolics in Olea europaea leaf extract. , 2010, Bioresource technology.

[3]  T. Riley,et al.  Antimicrobial activity of commercial Olea europaea (olive) leaf extract. , 2009, International journal of antimicrobial agents.

[4]  A. Tsarbopoulos,et al.  Conformation of oleuropein, the major bioactive compound of Olea europea , 2007 .

[5]  M. Alsina,et al.  Interaction between the antibacterial compound, oleuropein, and model membranes , 2007 .

[6]  S. Lee-Huang,et al.  Computational study of bindings of olive leaf extract (OLE) to HIV‐1 fusion protein gp41 , 2007, FEBS letters.

[7]  L. Estevinho,et al.  Phenolic compounds and antimicrobial activity of olive (Olea europaea L. Cv. Cobrançosa) leaves. , 2007, Molecules.

[8]  S. Lee-Huang,et al.  Discovery of small-molecule HIV-1 fusion and integrase inhibitors oleuropein and hydroxytyrosol: Part I. Integrase inhibition , 2007, Biochemical and Biophysical Research Communications.

[9]  S. Lee-Huang,et al.  Discovery of small-molecule HIV-1 fusion and integrase inhibitors oleuropein and hydroxytyrosol: Part I. Integrase inhibition , 2007, Biochemical and Biophysical Research Communications.

[10]  L. Estevinho,et al.  Phenolics and antimicrobial activity of traditional stoned table olives 'alcaparra'. , 2006, Bioorganic & medicinal chemistry.

[11]  J. Bradford,et al.  Changes in oleuropein levels during differentiation and development of floral buds in ‘Arbequina’ olives , 2006 .

[12]  L. Estevinho,et al.  Table olives from Portugal: phenolic compounds, antioxidant potential, and antimicrobial activity. , 2006, Journal of agricultural and food chemistry.

[13]  K. Markides,et al.  Noncovalent interaction between amyloid-β-peptide (1–40) and oleuropein studied by electrospray ionization mass spectrometry , 2006, Journal of the American Society for Mass Spectrometry.

[14]  M D Luque de Castro,et al.  Dynamic ultrasound-assisted extraction of oleuropein and related biophenols from olive leaves. , 2006, Journal of chromatography. A.

[15]  R. Keast,et al.  Phytochemistry: Ibuprofen-like activity in extra-virgin olive oil , 2005, Nature.

[16]  G. Tabacchi,et al.  The phenolic compounds of olive oil: structure, biological activity and beneficial effects on human health , 2005, Nutrition Research Reviews.

[17]  L. Perez,et al.  The olive leaf extract exhibits antiviral activity against viral haemorrhagic septicaemia rhabdovirus (VHSV). , 2005, Antiviral research.

[18]  G. Laufenberg,et al.  Antifungal activity of phenolic compounds extracted from dried olive pomace , 2005 .

[19]  F. Priego-Capote,et al.  Fast separation and determination of phenolic compounds by capillary electrophoresis-diode array detection. Application to the characterisation of alperujo after ultrasound-assisted extraction. , 2004, Journal of chromatography. A.

[20]  S. Lee-Huang,et al.  Anti-HIV activity of olive leaf extract (OLE) and modulation of host cell gene expression by HIV-1 infection and OLE treatment. , 2003, Biochemical and biophysical research communications.

[21]  R. de Caterina,et al.  Olive Oil and Red Wine Antioxidant Polyphenols Inhibit Endothelial Activation: Antiatherogenic Properties of Mediterranean Diet Phytochemicals , 2003, Arteriosclerosis, thrombosis, and vascular biology.

[22]  K. Tuck,et al.  Major phenolic compounds in olive oil: metabolism and health effects. , 2002, The Journal of nutritional biochemistry.

[23]  A. Saija,et al.  In vitro antimycoplasmal activity of oleuropein. , 2002, International journal of antimicrobial agents.

[24]  F. Visioli,et al.  Antioxidant and other biological activities of phenols from olives and olive oil , 2002, Medicinal research reviews.

[25]  H. Bartsch,et al.  Olive-oil consumption and health: the possible role of antioxidants. , 2000, The Lancet. Oncology.

[26]  A. Saija,et al.  On the In‐vitro Antimicrobial Activity of Oleuropein and Hydroxytyrosol , 1999, The Journal of pharmacy and pharmacology.

[27]  K. Robards,et al.  Changes in phenolic content of olive during maturation , 1999 .

[28]  A. Castro,et al.  Transformation of oleuropein and its hydrolysis products during Spanish‐style green olive processing , 1998 .

[29]  D. Trombetta,et al.  `In vitro' evaluation of the antioxidant activity and biomembrane interaction of the plant phenols oleuropein and hydroxytyrosol , 1998 .

[30]  V. Marsilio,et al.  Characterisation of an oleuropein degrading strain of Lactobacillus plantarum. Combined effects of compounds present in olive fermenting brines (phenols, glucose and NaCl) on bacterial activity , 1998 .

[31]  M. Esti,et al.  Phenolic Compounds in Different Olive Varieties. , 1998, Journal of agricultural and food chemistry.

[32]  F. Visioli,et al.  Oleuropein, the bitter principle of olives, enhances nitric oxide production by mouse macrophages. , 1998, Life sciences.

[33]  S. Denyer,et al.  Mechanisms of action of disinfectants , 1998 .

[34]  M. A. Abo-Zaid,et al.  Comparative antibacterial and antifungal effects of some phenolic compounds. , 1998, Microbios.

[35]  M. Brenes,et al.  Biochemical Changes in Phenolic Compounds during Spanish-Style Green Olive Processing , 1995 .

[36]  H. Franzyk,et al.  Biosynthesis of iridoids in Syringa and Fraxinus: Carbocyclic iridoid precursors , 1995 .

[37]  G. Bellomo,et al.  Low density lipoprotein oxidation is inhibited in vitro by olive oil constituents. , 1995, Atherosclerosis.

[38]  C. Tassou,et al.  Inhibition of Salmonella enteritidis by oleuropein in broth and in a model food system , 1995, Letters in applied microbiology.

[39]  A. Bianco,et al.  Isolation of cornoside from olea europaea and its transformation into halleridone , 1993 .

[40]  H. Franzyk,et al.  Excelsioside, a secoiridoid glucoside from Fraxinus excelsior , 1992 .

[41]  G. Nychas,et al.  Effect of phenolic compounds and oleuropein on the germination of Bacillus cereus T spores , 1991, Biotechnology and applied biochemistry.

[42]  A. Garrido-Fernández,et al.  Bactericidal action of oleuropein extracted from green olives against Lactobacillus plantarum , 1991 .

[43]  J. Macheix,et al.  The technological debittering process of olives characterization of fruits before and during alkaline treatment , 1990 .

[44]  M. Amiot,et al.  Accumulation of oleuropein derivatives during olive maturation , 1989 .

[45]  M. Amiot,et al.  Importance and evolution of phenolic compounds in olive during growth and maturation , 1986 .

[46]  H. Renis.  Inactivation of Myxoviruses by Calcium Elenolate , 1975, Antimicrobial Agents and Chemotherapy.

[47]  J. L. Etchells,et al.  Antimicrobial properties of oleuropein and products of its hydrolysis from green olives. , 1973, Applied microbiology.

[48]  Y. Henis,et al.  Studies on the mechanism of the antimicrobial action of oleuropein. , 1972, The Journal of applied bacteriology.

[49]  Y. Henis,et al.  Studies on the antimicrobial activity of olive phenolic compounds. , 1970, The Journal of applied bacteriology.

[50]  J. L. Etchells,et al.  Occurrence of an inhibitor of lactic Acid bacteria in green olives. , 1967, Applied microbiology.