Cryosurgical Ablation of the AV Node-His Bundle A New Method for Producing AV Block

A cryosurgical instrument was used to ablate atrioventricular conduction. The procedure was carried out in 20 dogs and subsequently in three patients with drug resistant, life-threatening supraventricular tachycardias. In patients, the cryosurgical unit lowered the temperature of the His bundle area to 0°C, effecting complete but reversible heart block. Rewarming resulted in resumption of normal atrioventricular conduction. The His bundle region then was cooled to -60°C; complete heart block was produced with

[1]  S. King,et al.  Disabling Supraventricular Tachycardia of Wolff‐Parkinson‐White Syndrome (Type A) Controlled by Surgical A‐V Block and a Demand Pacemaker after Epicardial Mapping Studies , 1972, Circulation.

[2]  I. S. Cooper,et al.  Effects of Freezing on Major Arteries , 1971, Stroke.

[3]  J. S. Cole,et al.  The Wolff-Parkinson-White syndrome: Problems in evaluation and surgical therapy , 1970 .

[4]  Thomas L. Crews,et al.  Surgically Induced Atrioventricular Block as Treatment for Recurrent Atrial Tachycardia in Wolff‐Parkinson‐White Syndrome , 1969, Circulation.

[5]  L. Dreifus,et al.  Control of Recurrent Tachycardia of Wolff‐Parkinson‐White Syndrome by Surgical Ligature of the A‐V Bundle , 1968, Circulation.

[6]  A. Kovalik,et al.  A simple technique for production of chronic complete heart block in dogs. , 1968, Journal of applied physiology.

[7]  J. Pruett,et al.  Technique for experimental complete heart block. , 1967, Journal of applied physiology.

[8]  S. Ayres,et al.  Therapeutic surgical division of the human conduction system. , 1967, JAMA.

[9]  J. Wieberdink.  Experimental production of permanent heart block (total or bundle branch block) without circulatory arrest or extracorporeal circulation. , 1966, Thorax.

[10]  R. Lee,et al.  Production of chronic atrioventricular block in dogs without thoracotomy. , 1966, Journal of applied physiology.

[11]  K. Hashiba,et al.  ATRIO-VENTICULAR BLOCK PRODUCED BY LIGATION OF SEPTAL ARTERIES IN THE DOG=. , 1965, Japanese heart journal.

[12]  J. Sommer,et al.  Thirty-five MM. film as mounting base and plastic spray as cover glass for histologic sections. , 1960, Archives of pathology.

[13]  J. W. West,et al.  Cardiac Effects of Isoproterenol, Norepinephrine and Epinephrine in Complete A‐V Heart Block During Experimental Acidosis and Hyperkalemia , 1959, Circulation research.

[14]  V. Gott,et al.  The treatment of complete heart block by the combined use of a myocardial electrode and an artificial pacemaker. , 1957, Surgical forum.

[15]  T. Starzl,et al.  Chronic Heart Block in Dogs. A Method for Producing Experimental Heart Failure , 1955, Circulation.

[16]  M. Lev,et al.  A method for the histopathologic study of the atrioventricular node, bundle, and branches. , 1951, A.M.A. archives of pathology.

[17]  G. Vawter,et al.  Controlled Myocardial Injury Produced by a Hypothermal Method , 1951, Circulation.

[18]  C. B. Taylor,et al.  A quantitative hypothermal method for production of local injury to tissue. , 1947, Federation proceedings.