Dysregulation of germinal centres in autoimmune disease
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M. Cook | C. Vinuesa | I. Sanz
[1] S. Tangye,et al. Dock8 mutations cripple B cell immunological synapses, germinal centers and long-lived antibody production , 2009, Nature Immunology.
[2] C. King,et al. New insights into the differentiation and function of T follicular helper cells , 2009, Nature Reviews Immunology.
[3] Lawrence Steinman,et al. PPAR-δ senses and orchestrates clearance of apoptotic cells to promote tolerance , 2009, Nature Medicine.
[4] C. Mackay,et al. The transcriptional repressor Bcl-6 directs T follicular helper cell lineage commitment. , 2009, Immunity.
[5] R. Brink,et al. Antigen Affinity Controls Rapid T-Dependent Antibody Production by Driving the Expansion Rather than the Differentiation or Extrafollicular Migration of Early Plasmablasts1 , 2009, The Journal of Immunology.
[6] C. Mackay,et al. Guidance of B cells by the orphan G protein-coupled receptor EBI2 shapes humoral immune responses. , 2009, Immunity.
[7] Kenneth G. C. Smith,et al. Faculty Opinions recommendation of EBI2 mediates B cell segregation between the outer and centre follicle. , 2009 .
[8] D. Gray,et al. B Cell Intrinsic MyD88 Signals Drive IFN-γ Production from T Cells and Control Switching to IgG2c1 , 2009, The Journal of Immunology.
[9] B. Cubelos,et al. Essential function for the GTPase TC21 in homeostatic antigen receptor signaling , 2009, Nature Immunology.
[10] K. Tarte,et al. CXCR4 Expression Functionally Discriminates Centroblasts versus Centrocytes within Human Germinal Center B Cells1 , 2009, The Journal of Immunology.
[11] R. Fietkau,et al. Remnants of secondarily necrotic cells fuel inflammation in systemic lupus erythematosus. , 2009, Arthritis and rheumatism.
[12] I. Vajtai,et al. Class-switched B cells display response to therapeutic B-cell depletion in rheumatoid arthritis , 2009, Arthritis research & therapy.
[13] F. Batista,et al. BCR-mediated uptake of antigen linked to TLR9 ligand stimulates B-cell proliferation and antigen-specific plasma cell formation. , 2009, Blood.
[14] N. Fazilleau,et al. Follicular helper T cells: lineage and location. , 2009, Immunity.
[15] M. Cook,et al. Follicular helper T cells are required for systemic autoimmunity , 2009, The Journal of experimental medicine.
[16] B. Rapoport,et al. Evidence that shed thyrotropin receptor A subunits drive affinity maturation of autoantibodies causing Graves' disease. , 2009, The Journal of clinical endocrinology and metabolism.
[17] N. Fazilleau,et al. The function of follicular helper T cells is regulated by the strength of T cell antigen receptor binding , 2009, Nature Immunology.
[18] György Vereb,et al. Transglutaminase 2 Is Needed for the Formation of an Efficient Phagocyte Portal in Macrophages Engulfing Apoptotic Cells1 , 2009, The Journal of Immunology.
[19] W. Leonard,et al. A critical role for IL-21 receptor signaling in the pathogenesis of systemic lupus erythematosus in BXSB-Yaa mice , 2009, Proceedings of the National Academy of Sciences.
[20] G. Kollias,et al. Induction of autoantibody-mediated spontaneous arthritis critically depends on follicular dendritic cells. , 2009, Immunity.
[21] Stephen Kelly,et al. Ectopic Lymphoid Structures Support Ongoing Production of Class-Switched Autoantibodies in Rheumatoid Synovium , 2009, PLoS medicine.
[22] A. Puisieux,et al. Interleukin 17 acts in synergy with B cell–activating factor to influence B cell biology and the pathophysiology of systemic lupus erythematosus , 2009, Nature Immunology.
[23] P. Gaffney,et al. Complement receptor 2 polymorphisms associated with systemic lupus erythematosus modulate alternative splicing , 2009, Genes and Immunity.
[24] Hai Qi,et al. SLAM receptors and SAP influence lymphocyte interactions, development and function , 2009, Nature Reviews Immunology.
[25] R. Eisenberg,et al. T Cell-Independent Spontaneous Loss of Tolerance by Anti-Double-Stranded DNA B Cells in C57BL/6 Mice1 , 2008, The Journal of Immunology.
[26] R. Flavell,et al. ICOS-dependent extrafollicular helper T cells elicit IgG production via IL-21 in systemic autoimmunity , 2008, The Journal of experimental medicine.
[27] H. Weiner,et al. Nasal Anti-CD3 Antibody Ameliorates Lupus by Inducing an IL-10-Secreting CD4+CD25−LAP+ Regulatory T Cell and Is Associated with Down-Regulation of IL-17+CD4+ICOS+CXCR5+ Follicular Helper T Cells1 , 2008, The Journal of Immunology.
[28] K. Rajewsky,et al. Fas receptor expression in germinal-center B cells is essential for T and B lymphocyte homeostasis. , 2008, Immunity.
[29] T. Manser,et al. Influence of Fas on the regulation of the response of an anti-nuclear antigen B cell clonotype to foreign antigen. , 2008, International immunology.
[30] Uri Hershberg,et al. T cell-independent and toll-like receptor-dependent antigen-driven activation of autoreactive B cells. , 2008, Immunity.
[31] V. Pascual,et al. Autoreactive IgG memory antibodies in patients with systemic lupus erythematosus arise from nonreactive and polyreactive precursors , 2008, Proceedings of the National Academy of Sciences.
[32] P. Tak,et al. B Lymphocyte Autoimmunity in Rheumatoid Synovitis Is Independent of Ectopic Lymphoid Neogenesis1 , 2008, The Journal of Immunology.
[33] John E. Connolly,et al. Yaa autoimmune phenotypes are conferred by overexpression of TLR7 , 2008, European journal of immunology.
[34] A. Aguzzi,et al. Follicular dendritic cells control engulfment of apoptotic bodies by secreting Mfge8 , 2008, The Journal of experimental medicine.
[35] Uri Hershberg,et al. Improved methods for detecting selection by mutation analysis of Ig V region sequences. , 2008, International immunology.
[36] Andreas Radbruch,et al. Plasma cell differentiation and survival. , 2008, Current opinion in immunology.
[37] M. McDermott. Faculty Opinions recommendation of Cutting edge: anti-tumor necrosis factor therapy in rheumatoid arthritis inhibits memory B lymphocytes via effects on lymphoid germinal centers and follicular dendritic cell networks. , 2008 .
[38] D. Rawlings,et al. B cell autonomous TLR signaling and autoimmunity. , 2008, Autoimmunity reviews.
[39] D. Tarlinton. IL-17 drives germinal center B cells? , 2008, Nature Immunology.
[40] Robert W. Williams,et al. Interleukin 17–producing T helper cells and interleukin 17 orchestrate autoreactive germinal center development in autoimmune BXD2 mice , 2008, Nature Immunology.
[41] M. Shlomchik,et al. Sites and stages of autoreactive B cell activation and regulation. , 2008, Immunity.
[42] A. Almudevar,et al. Cutting Edge: Anti-Tumor Necrosis Factor Therapy in Rheumatoid Arthritis Inhibits Memory B Lymphocytes via Effects on Lymphoid Germinal Centers and Follicular Dendritic Cell Networks1 , 2008, The Journal of Immunology.
[43] M. Drayson,et al. Levels of autoantibodies, unlike antibodies to all extrinsic antigen groups, fall following B cell depletion with Rituximab , 2008, European journal of immunology.
[44] D. Rawlings,et al. B cell–intrinsic TLR signals amplify but are not required for humoral immunity , 2007, The Journal of experimental medicine.
[45] A. Strasser,et al. Proapoptotic BH3-only protein Bim is essential for developmentally programmed death of germinal center-derived memory B cells and antibody-forming cells. , 2007, Blood.
[46] T. Manser,et al. Expression of the autoimmune Fcgr2b NZW allele fails to be upregulated in germinal center B cells and is associated with increased IgG production , 2007, Genes and Immunity.
[47] I. Sanz,et al. Delayed memory B cell recovery in peripheral blood and lymphoid tissue in systemic lupus erythematosus after B cell depletion therapy. , 2007, Arthritis and rheumatism.
[48] J. Cyster,et al. Germinal-center organization and cellular dynamics. , 2007, Immunity.
[49] C. Mackay,et al. BAFF and MyD88 signals promote a lupuslike disease independent of T cells , 2007, The Journal of experimental medicine.
[50] T. Yoshino,et al. Expression of apoptosis regulators in germinal centers and germinal center‐derived B‐cell lymphomas: Insight into B‐cell lymphomagenesis , 2007, Pathology international.
[51] M. Shlomchik,et al. In vivo imaging studies shed light on germinal-centre development , 2007, Nature Reviews Immunology.
[52] R. Kimberly,et al. Expression Profile of FcγRIIb on Leukocytes and Its Dysregulation in Systemic Lupus Erythematosus1 , 2007, The Journal of Immunology.
[53] M. Radic,et al. Divergent members of a single autoreactive B cell clone retain specificity for apoptotic blebs. , 2007, Molecular immunology.
[54] M. Nussenzweig,et al. Autoreactivity in human IgG+ memory B cells. , 2007, Immunity.
[55] D. Tarlinton. B-cell memory: are subsets necessary? , 2006, Nature Reviews Immunology.
[56] B. Diamond,et al. Selective dysregulation of the FcγIIB receptor on memory B cells in SLE , 2006, The Journal of Experimental Medicine.
[57] J. Shupe,et al. Toll-like receptor 7 and TLR9 dictate autoantibody specificity and have opposing inflammatory and regulatory roles in a murine model of lupus. , 2006, Immunity.
[58] Dagmar Iber,et al. An analysis of B cell selection mechanisms in germinal centers. , 2006, Mathematical medicine and biology : a journal of the IMA.
[59] Quanzhen Li,et al. A Tlr7 translocation accelerates systemic autoimmunity in murine lupus. , 2006, Proceedings of the National Academy of Sciences of the United States of America.
[60] A. Satterthwaite,et al. Autoreactive B Cell Responses to RNA-Related Antigens Due to TLR7 Gene Duplication , 2006, Science.
[61] O. Rekvig,et al. Cardiovascular, Pulmonary and Renal Pathology Nephritogenic Lupus Antibodies Recognize Glomerular Basement Membrane-Associated Chromatin Fragments Released from Apoptotic Intraglomerular Cells , 2006 .
[62] S. Liao,et al. Lymphoid organ development: from ontogeny to neogenesis , 2006, Nature Immunology.
[63] F. Aloisi,et al. Lymphoid neogenesis in chronic inflammatory diseases , 2006, Nature Reviews Immunology.
[64] M. Dougados,et al. Serial determination of cyclic citrullinated peptide autoantibodies predicted five-year radiological outcomes in a prospective cohort of patients with early rheumatoid arthritis , 2006, Arthritis research & therapy.
[65] R. Voll,et al. Clearance of apoptotic cells in human SLE. , 2006, Current directions in autoimmunity.
[66] S. Akira,et al. RNA-associated autoantigens activate B cells by combined B cell antigen receptor/Toll-like receptor 7 engagement , 2005, The Journal of experimental medicine.
[67] J. Connell,et al. Association of the TSHR gene with Graves' disease: the first disease specific locus , 2005, European Journal of Human Genetics.
[68] A. Cappione,et al. Germinal center exclusion of autoreactive B cells is defective in human systemic lupus erythematosus. , 2005, The Journal of clinical investigation.
[69] C. Mackay,et al. Follicular B helper T cells in antibody responses and autoimmunity , 2005, Nature Reviews Immunology.
[70] S. Akira,et al. Nucleic acids of mammalian origin can act as endogenous ligands for Toll-like receptors and may promote systemic lupus erythematosus , 2005, The Journal of experimental medicine.
[71] T. Winkler,et al. The evolution of human anti-double-stranded DNA autoantibodies. , 2005, Proceedings of the National Academy of Sciences of the United States of America.
[72] J. Kearney. Faculty Opinions recommendation of Short-lived plasmablasts dominate the early spontaneous rheumatoid factor response: differentiation pathways, hypermutating cell types, and affinity maturation outside the germinal center. , 2005 .
[73] Chad W. Euler,et al. Short-Lived Plasmablasts Dominate the Early Spontaneous Rheumatoid Factor Response: Differentiation Pathways, Hypermutating Cell Types, and Affinity Maturation Outside the Germinal Center1 , 2005, The Journal of Immunology.
[74] R. Copley,et al. A RING-type ubiquitin ligase family member required to repress follicular helper T cells and autoimmunity , 2005, Nature.
[75] J. Witztum,et al. Apoptotic Cells with Oxidation-specific Epitopes Are Immunogenic and Proinflammatory , 2004, The Journal of experimental medicine.
[76] P. Hillsamer,et al. Regulatory T cells can migrate to follicles upon T cell activation and suppress GC-Th cells and GC-Th cell-driven B cell responses. , 2004, The Journal of clinical investigation.
[77] J. Cyster,et al. Germinal center dark and light zone organization is mediated by CXCR4 and CXCR5 , 2004, Nature Immunology.
[78] B. Eymard,et al. Genetic control of autoantibody expression in autoimmune myasthenia gravis: role of the self-antigen and of HLA-linked loci , 2004, Genes and Immunity.
[79] Andreas Radbruch,et al. Short-lived Plasmablasts and Long-lived Plasma Cells Contribute to Chronic Humoral Autoimmunity in NZB/W Mice , 2004, The Journal of Experimental Medicine.
[80] Michael Loran Dustin,et al. LFA-1/ICAM-1 interaction lowers the threshold of B cell activation by facilitating B cell adhesion and synapse formation. , 2004, Immunity.
[81] J. Cyster,et al. Reduced competitiveness of autoantigen-engaged B cells due to increased dependence on BAFF. , 2004, Immunity.
[82] J. Laman,et al. The Guillain-Barré syndrome: a true case of molecular mimicry. , 2004, Trends in immunology.
[83] L. Skrabanek,et al. Amino acid substitutions in the thyroglobulin gene are associated with susceptibility to human and murine autoimmune thyroid disease , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[84] R. Jonsson,et al. Cellular basis of ectopic germinal center formation and autoantibody production in the target organ of patients with Sjögren's syndrome. , 2003, Arthritis and rheumatism.
[85] M. Nussenzweig,et al. Predominant Autoantibody Production by Early Human B Cell Precursors , 2003, Science.
[86] M. Leandro,et al. Serologic changes following B lymphocyte depletion therapy for rheumatoid arthritis. , 2003, Arthritis and rheumatism.
[87] Karin Reiter,et al. Correlation between circulating CD27high plasma cells and disease activity in patients with systemic lupus erythematosus. , 2003, Arthritis and rheumatism.
[88] K. Toellner,et al. Established T Cell-Driven Germinal Center B Cell Proliferation Is Independent of CD28 Signaling but Is Tightly Regulated Through CTLA-41 , 2003, The Journal of Immunology.
[89] P. Plotz,et al. The autoantibody repertoire: searching for order , 2003, Nature Reviews Immunology.
[90] P. Lipsky,et al. Abnormal germinal center reactions in systemic lupus erythematosus demonstrated by blockade of CD154-CD40 interactions. , 2003, The Journal of clinical investigation.
[91] K. Sugamura,et al. Constitutive OX40/OX40 Ligand Interaction Induces Autoimmune-Like Diseases1 , 2002, The Journal of Immunology.
[92] Anthony E. Boitano,et al. Benzodiazepine-induced superoxide signals B cell apoptosis: mechanistic insight and potential therapeutic utility. , 2002, The Journal of clinical investigation.
[93] Chad W. Euler,et al. Evolution of Autoantibody Responses via Somatic Hypermutation Outside of Germinal Centers , 2002, Science.
[94] B. Nardelli,et al. DCs induce CD40-independent immunoglobulin class switching through BLyS and APRIL , 2002, Nature Immunology.
[95] B. Rapoport,et al. Thyroid-stimulating autoantibodies in Graves disease preferentially recognize the free A subunit, not the thyrotropin holoreceptor. , 2002, The Journal of clinical investigation.
[96] R. Furie,et al. The effect of anti-CD40 ligand antibody on B cells in human systemic lupus erythematosus. , 2002, Arthritis and rheumatism.
[97] M. Shlomchik,et al. Chromatin–IgG complexes activate B cells by dual engagement of IgM and Toll-like receptors , 2002, Nature.
[98] I. Baumann,et al. Impaired uptake of apoptotic cells into tingible body macrophages in germinal centers of patients with systemic lupus erythematosus. , 2002, Arthritis and rheumatism.
[99] Y. Tomer,et al. Thyroglobulin is a thyroid specific gene for the familial autoimmune thyroid diseases. , 2002, The Journal of clinical endocrinology and metabolism.
[100] G. Kelsoe,et al. Spontaneous formation of germinal centers in autoimmune mice , 2001, Journal of leukocyte biology.
[101] A. Cappione,et al. Regulation of inherently autoreactive VH4-34 B cells in the maintenance of human B cell tolerance. , 2001, The Journal of clinical investigation.
[102] C. Weyand,et al. Ectopic lymphoid organogenesis: a fast track for autoimmunity. , 2001, The American journal of pathology.
[103] M. Juan,et al. Thyroid autoimmune disease: demonstration of thyroid antigen-specific B cells and recombination-activating gene expression in chemokine-containing active intrathyroidal germinal centers. , 2001, The American journal of pathology.
[104] V. Pascual,et al. Increased Frequency of Pre-germinal Center B Cells and Plasma Cell Precursors in the Blood of Children with Systemic Lupus Erythematosus1 , 2001, The Journal of Immunology.
[105] R. Scott,et al. Phagocytosis and clearance of apoptotic cells is mediated by MER , 2001, Nature.
[106] Y. Takahashi,et al. Fas is required for clonal selection in germinal centers and the subsequent establishment of the memory B cell repertoire. , 2001, Immunity.
[107] C. Wong,et al. Elevation of proinflammatory cytokine (IL-18, IL-17, IL-12) and Th2 cytokine (IL-4) concentrations in patients with systemic lupus erythematosus , 2000, Lupus.
[108] J. Ravetch,et al. Spontaneous autoimmune disease in Fc(gamma)RIIB-deficient mice results from strain-specific epistasis. , 2000, Immunity.
[109] P. Taylor,et al. A Hierarchical Role for Classical Pathway Complement Proteins in the Clearance of Apoptotic Cells in Vivo , 2000, The Journal of experimental medicine.
[110] Jason G. Cyster,et al. A chemokine-driven positive feedback loop organizes lymphoid follicles , 2000, Nature.
[111] M. Madaio,et al. Alterations in splenic architecture and the localization of anti-double-stranded DNA B cells in aged mice. , 2000, International immunology.
[112] T. Möröy,et al. Features of systemic lupus erythematosus in Dnase1-deficient mice , 2000, Nature Genetics.
[113] P. Anderson,et al. Death, autoantigen modifications, and tolerance , 2000, Arthritis research.
[114] Kenneth G. C. Smith,et al. bcl-2 Transgene Expression Inhibits Apoptosis in the Germinal Center and Reveals Differences in the Selection of Memory B Cells and Bone Marrow Antibody-Forming Cells , 2000, The Journal of experimental medicine.
[115] R. Zinkernagel,et al. Antiviral B Cell Memory in the Absence of Mature Follicular Dendritic Cell Networks and Classical Germinal Centers in TNFR1−/− Mice1 , 2000, The Journal of Immunology.
[116] B. Tsao. Lupus Susceptibility Genes on Human Chromosome 1 , 2000, International reviews of immunology.
[117] S. Hirose,et al. Genetically determined aberrant down-regulation of FcgammaRIIB1 in germinal center B cells associated with hyper-IgG and IgG autoantibodies in murine systemic lupus erythematosus. , 1999, International immunology.
[118] T. Behrens,et al. Relaxed Negative Selection in Germinal Centers and Impaired Affinity Maturation in bcl-x L Transgenic Mice , 1999, The Journal of experimental medicine.
[119] C. Sokol,et al. MRL-lpr/lpr Mice Exhibit a Defect in Maintaining Developmental Arrest and Follicular Exclusion of Anti–double-stranded DNA B Cells , 1999, The Journal of experimental medicine.
[120] M. Riedinger,et al. CD4 T cell traffic control: in vivo evidence that ligation of OX40 on CD4 T cells by OX40‐ligand expressed on dendritic cells leads to the accumulation of CD4 T cells in B follicles , 1999, European journal of immunology.
[121] T. Yoshino,et al. Deletion of Fcγ Receptor IIB Renders H-2b Mice Susceptible to Collagen-induced Arthritis , 1999, The Journal of experimental medicine.
[122] L. Staudt,et al. Regulation of lymphocyte cell fate decisions and lymphomagenesis by BCL-6. , 1999, International reviews of immunology.
[123] C. Berek,et al. Antigen-driven clonal proliferation of B cells within the target tissue of an autoimmune disease. The salivary glands of patients with Sjögren's syndrome. , 1998, The Journal of clinical investigation.
[124] K. Toellner,et al. T Helper 1 (th1) and Th2 Characteristics Start to Develop during T Cell Priming and Are Associated with an Immediate Ability to Induce Immunoglobulin Class Switching , 1998 .
[125] T. Manser,et al. Bcl-2 obstructs negative selection of autoreactive, hypermutated antibody V regions during memory B cell development. , 1998, Immunity.
[126] M. Cook,et al. Outer Periarteriolar Lymphoid Sheath Arrest and Subsequent Differentiation of Both Naive and Tolerant Immunoglobulin Transgenic B Cells Is Determined by B Cell Receptor Occupancy , 1997, The Journal of experimental medicine.
[127] A. Marshak‐Rothstein,et al. Unique site of IgG2a and rheumatoid factor production in MRL/lpr mice , 1997, Immunological reviews.
[128] D. Chaplin,et al. Lymphotoxin‐α‐deficient and TNF receptor‐I‐deficient mice define developmental and functional characteristics of germinal centers , 1997, Immunological reviews.
[129] A. Weetman,et al. Cloning and analysis of IgG kappa and IgG lambda anti-thyroglobulin autoantibodies from a patient with Hashimoto's thyroiditis: evidence for in vivo antigen-driven repertoire selection. , 1996, Journal of immunology.
[130] A. B. Lyons,et al. The fate of self-reactive B cells depends primarily on the degree of antigen receptor engagement and availability of T cell help , 1996, The Journal of experimental medicine.
[131] B. Diamond,et al. Pathogenic autoantibodies are routinely generated during the response to foreign antigen: a paradigm for autoimmune disease. , 1996, Proceedings of the National Academy of Sciences of the United States of America.
[132] G. Kelsoe,et al. In situ studies of the primary immune response to (4-hydroxy-3- nitrophenyl)acetyl. IV. Affinity-dependent, antigen-driven B cell apoptosis in germinal centers as a mechanism for maintaining self- tolerance , 1995, The Journal of experimental medicine.
[133] K. Shokat,et al. Antigen-induced B-cell death and elimination during germinal-centre immune responses , 1995, Nature.
[134] Kenneth G. C. Smith,et al. Soluble antigen can cause enhanced apoptosis of germinal-centre B cells , 1995, Nature.
[135] M. Kosco‐Vilbois,et al. Follicular dendritic cells: antigen retention, B cell activation, and cytokine production. , 1995, Current topics in microbiology and immunology.
[136] M. Shlomchik,et al. The role of B cells in lpr/lpr-induced autoimmunity , 1994, The Journal of experimental medicine.
[137] D. Loh,et al. Visualization of peptide-specific T cell immunity and peripheral tolerance induction in vivo. , 1994, Immunity.
[138] W. Newman,et al. Adhesion through the LFA-1 (CD11a/CD18)-ICAM-1 (CD54) and the VLA-4 (CD49d)-VCAM-1 (CD106) pathways prevents apoptosis of germinal center B cells. , 1994, Journal of immunology.
[139] A. Rosen,et al. Autoantigens targeted in systemic lupus erythematosus are clustered in two populations of surface structures on apoptotic keratinocytes , 1994, The Journal of experimental medicine.
[140] N. Jenkins,et al. Generalized lymphoproliferative disease in mice, caused by a point mutation in the fas ligand , 1994, Cell.
[141] C Bona,et al. Defining criteria for autoimmune diseases (Witebsky's postulates revisited) , 1993, Immunology today.
[142] G. Nossal,et al. Antigen-driven B cell differentiation in vivo , 1993, The Journal of experimental medicine.
[143] N. Copeland,et al. Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis , 1992, Nature.
[144] T. Olee,et al. Genetic analysis of self-associating immunoglobulin G rheumatoid factors from two rheumatoid synovia implicates an antigen-driven response , 1992, The Journal of experimental medicine.
[145] C. Goodnow,et al. Induction of self-tolerance in T cells but not B cells of transgenic mice expressing little self antigen. , 1991, Science.
[146] S. Behar,et al. Characterization of somatically mutated S107 VH11-encoded anti-DNA autoantibodies derived from autoimmune (NZB x NZW)F1 mice , 1991, The Journal of experimental medicine.
[147] D. Pisetsky,et al. Anti-DNA antibodies from autoimmune mice arise by clonal expansion and somatic mutation , 1990, The Journal of experimental medicine.
[148] C. Janeway,et al. IgG anti-DNA autoantibodies within an individual autoimmune mouse are the products of clonal selection. , 1989, Journal of immunology.
[149] Thomas L. Rothstein,et al. The role of clonal selection and somatic mutation in autoimmunity , 1987, Nature.
[150] D. Gray,et al. Antigen‐Driven Selection of Virgin and Memory B Cells , 1986, Immunological reviews.
[151] R. Cote,et al. Specificity analysis of human monoclonal antibodies reactive with cell surface and intracellular antigens. , 1986, Proceedings of the National Academy of Sciences of the United States of America.
[152] A. Coutinho,et al. High frequency of natural autoantibodies in normal newborn mice. , 1985, Journal of immunology.
[153] B. Diamond,et al. Somatic mutation of the T15 heavy chain gives rise to an antibody with autoantibody specificity. , 1984, Proceedings of the National Academy of Sciences of the United States of America.
[154] D. Baltimore,et al. Heavy chain variable region contribution to the NPb family of antibodies: somatic mutation evident in a γ2a variable region , 1981, Cell.
[155] Leroy Hood,et al. IgG antibodies to phosphorylcholine exhibit more diversity than their IgM counterparts , 1981, Nature.
[156] C. Arnaud,et al. An approach to the structure of thyroglobulin. Hormone-forming sequences in porcine thyroglobulin. , 2005, European journal of biochemistry.
[157] L. Hammarström,et al. Characterization of self-reactive B cells by polyclonal B-cell activators , 1977, The Journal of experimental medicine.
[158] E. Cronkite,et al. CELL PROLIFERATION IN GERMINAL CENTERS OF THE RAT SPLEEN * , 1964, Annals of the New York Academy of Sciences.
[159] G. Thorbecke,et al. SOME HISTOLOGICAL AND FUNCTIONAL ASPECTS OF LYMPHOID TISSUE IN GERMFREE ANIMALS: II. STUDIES ON PHAGOCYTOSIS IN VIVO , 1959, Annals of the New York Academy of Sciences.
[160] G. Thorbecke. SOME HISTOLOGICAL AND FUNCTIONAL ASPECTS OF LYMPHOID TISSUE IN GERMFREE ANIMALS: I. MORPHOLOGICAL STUDIES* , 1959, Annals of the New York Academy of Sciences.
[161] N. Cozzarelli,et al. References and Notes Materials and Methods Figs. S1 to S4 Tables S1 and S2 References Sequence-directed Dna Translocation by Purified Ftsk , 2022 .