Potent inhibition of tumoral hypoxia-inducible factor 1α by albendazole
暂无分享,去创建一个
[1] N. Ferrara,et al. Tumor and stromal pathways mediating refractoriness/resistance to anti-angiogenic therapies. , 2009, Trends in pharmacological sciences.
[2] V. Heinemann,et al. Resistance to EGF-R (erbB-1) and VEGF-R modulating agents. , 2009, European journal of cancer.
[3] John M L Ebos,et al. Accelerated metastasis after short-term treatment with a potent inhibitor of tumor angiogenesis. , 2009, Cancer cell.
[4] Masahiro Inoue,et al. Antiangiogenic therapy elicits malignant progression of tumors to increased local invasion and distant metastasis. , 2009, Cancer cell.
[5] R. Kerbel,et al. Tumor-associated fibroblasts as "Trojan Horse" mediators of resistance to anti-VEGF therapy. , 2009, Cancer cell.
[6] M. Links,et al. Inhibition of Cell Proliferation, Vascular Endothelial Growth Factor and Tumor Growth by Albendazole , 2009, Cancer investigation.
[7] L. Ellis,et al. Pathways Mediating Resistance to Vascular Endothelial Growth Factor–Targeted Therapy , 2008, Clinical Cancer Research.
[8] G. Semenza. Hypoxia‐inducible factor 1 and cancer pathogenesis , 2008, IUBMB life.
[9] Giovanni Mazzoni,et al. Mebendazole inhibits growth of human adrenocortical carcinoma cell lines implanted in nude mice , 2008, Cancer Chemotherapy and Pharmacology.
[10] S. Vandenberg,et al. HIF1alpha induces the recruitment of bone marrow-derived vascular modulatory cells to regulate tumor angiogenesis and invasion. , 2008, Cancer cell.
[11] G. Semenza. Evaluation of HIF-1 inhibitors as anticancer agents. , 2007, Drug discovery today.
[12] D. Chung,et al. Hypoxia Inducible Factor-1–Independent Pathways in Tumor Angiogenesis , 2007, Clinical Cancer Research.
[13] D. Morris,et al. Epothilone-paclitaxel resistant leukemic cells CEM/dEpoB300 are sensitive to albendazole: Involvement of apoptotic pathways. , 2007, Biochemical pharmacology.
[14] R. Johnson,et al. Hypoxia: A key regulator of angiogenesis in cancer , 2007, Cancer and Metastasis Reviews.
[15] G. Melillo,et al. Inhibiting Hypoxia-Inducible Factor 1 for Cancer Therapy , 2006, Molecular Cancer Research.
[16] Lisa I. Wang,et al. Albendazole: a Potent Inhibitor of Vascular Endothelial Growth Factor and Malignant Ascites Formation in OVCAR-3 Tumor-Bearing Nude Mice , 2006, Clinical Cancer Research.
[17] Napoleone Ferrara,et al. VEGF as a Therapeutic Target in Cancer , 2005, Oncology.
[18] Peter Carmeliet,et al. VEGF as a Key Mediator of Angiogenesis in Cancer , 2005, Oncology.
[19] Oriol Casanovas,et al. Drug resistance by evasion of antiangiogenic targeting of VEGF signaling in late-stage pancreatic islet tumors. , 2005, Cancer cell.
[20] K. Kivirikko,et al. Effect of desferrioxamine and metals on the hydroxylases in the oxygen sensing pathway , 2005, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[21] B. Brüne,et al. Nitric oxide reverses desferrioxamine- and hypoxia-evoked HIF-1alpha accumulation--implications for prolyl hydroxylase activity and iron. , 2005, Experimental cell research.
[22] Lisa I. Wang,et al. Antitumor activity of albendazole against the human colorectal cancer cell line HT-29: in vitro and in a xenograft model of peritoneal carcinomatosis , 2005, Cancer Chemotherapy and Pharmacology.
[23] Richard P. Hill,et al. Acute Hypoxia Enhances Spontaneous Lymph Node Metastasis in an Orthotopic Murine Model of Human Cervical Carcinoma , 2004, Cancer Research.
[24] G. Semenza. Targeting HIF-1 for cancer therapy , 2003, Nature Reviews Cancer.
[25] P. Comoglio,et al. Hypoxia promotes invasive growth by transcriptional activation of the met protooncogene. , 2003, Cancer cell.
[26] J. Horton. Albendazole: a broad spectrum anthelminthic for treatment of individuals and populations , 2002, Current opinion in infectious diseases.
[27] Jack A Roth,et al. The anthelmintic drug mebendazole induces mitotic arrest and apoptosis by depolymerizing tubulin in non-small cell lung cancer cells. , 2002, Molecular cancer therapeutics.
[28] Jack A Roth,et al. Mebendazole elicits a potent antitumor effect on human cancer cell lines both in vitro and in vivo. , 2002, Clinical cancer research : an official journal of the American Association for Cancer Research.
[29] D. Morris,et al. Pilot Study of Albendazole in Patients with Advanced Malignancy , 2001, Oncology.
[30] D. Morris,et al. In vitro and in vivo suppression of growth of hepatocellular carcinoma cells by albendazole. , 2001, Cancer letters.
[31] Michael I. Wilson,et al. Targeting of HIF-α to the von Hippel-Lindau Ubiquitylation Complex by O2-Regulated Prolyl Hydroxylation , 2001, Science.
[32] G. Semenza,et al. Activation of vascular endothelial growth factor gene transcription by hypoxia-inducible factor 1 , 1996, Molecular and cellular biology.
[33] E. Keshet,et al. Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis , 1992, Nature.
[34] E. Lacey. The role of the cytoskeletal protein, tubulin, in the mode of action and mechanism of drug resistance to benzimidazoles. , 1988, International journal for parasitology.
[35] J. Folkman. Tumor angiogenesis: therapeutic implications. , 1971, The New England journal of medicine.
[36] N. Ferrara,et al. VEGF inhibition: insights from preclinical and clinical studies , 2008, Cell and Tissue Research.
[37] J. Folkman. Angiogenesis: an organizing principle for drug discovery? , 2007, Nature reviews. Drug discovery.
[38] A. Bikfalvi,et al. Tumor angiogenesis , 2020, Advances in cancer research.
[39] G. Semenza,et al. HIF-1: Using Two Hands to Flip the Angiogenic Switch , 2004, Cancer and Metastasis Reviews.
[40] R. L. Brady,et al. Comparison of inhibition of polymerisation of mammalian tubulin and helminth ovicidal activity by benzimidazole carbamates. , 1987, Veterinary parasitology.