Delphinidin, an active compound of red wine, inhibits endothelial cell apoptosis via nitric oxide pathway and regulation of calcium homeostasis

[1]  R. Andriantsitohaina,et al.  Delphinidin inhibits endothelial cell proliferation and cell cycle progression through a transient activation of ERK-1/-2. , 2003, Biochemical pharmacology.

[2]  Simon C Watkins,et al.  Hepatocyte Fas-associating Death Domain Protein/Mediator of Receptor-induced Toxicity (FADD/MORT1) Levels Increase in Response to Pro-apoptotic Stimuli* , 2002, The Journal of Biological Chemistry.

[3]  E. Gulbins,et al.  Actinomycin D-induced apoptosis involves the potassium channel Kv1.3. , 2002, Biochemical and biophysical research communications.

[4]  R. Andriantsitohaina,et al.  Red wine polyphenols increase calcium in bovine aortic endothelial cells: a basis to elucidate signalling pathways leading to nitric oxide production , 2002, British journal of pharmacology.

[5]  P. Babál,et al.  Wine polyphenols improve cardiovascular remodeling and vascular function in NO-deficient hypertension. , 2002, American journal of physiology. Heart and circulatory physiology.

[6]  J. Hayakawa,et al.  Induction of Endothelial Nitric-oxide Synthase Phosphorylation by the Raloxifene Analog LY117018 Is Differentially Mediated by Akt and Extracellular Signal-regulated Protein Kinase in Vascular Endothelial Cells* , 2001, The Journal of Biological Chemistry.

[7]  R. Andriantsitohaina,et al.  Wine Polyphenols Decrease Blood Pressure, Improve NO Vasodilatation, and Induce Gene Expression , 2001, Hypertension.

[8]  H. Inaba,et al.  Orally administered delphinidin 3-rutinoside and cyanidin 3-rutinoside are directly absorbed in rats and humans and appear in the blood as the intact forms. , 2001, Journal of agricultural and food chemistry.

[9]  D. Marko,et al.  The anthocyanidins cyanidin and delphinidin are potent inhibitors of the epidermal growth-factor receptor. , 2001, Journal of agricultural and food chemistry.

[10]  K. Wu,et al.  Up-regulation of Endothelial Nitric-oxide Synthase Promoter by the Phosphatidylinositol 3-Kinase γ/Janus Kinase 2/MEK-1-dependent Pathway* , 2001, The Journal of Biological Chemistry.

[11]  E. Middleton,et al.  The effects of plant flavonoids on mammalian cells: implications for inflammation, heart disease, and cancer. , 2000, Pharmacological reviews.

[12]  W. Ulrich,et al.  The inhibitory potency and selectivity of arginine substrate site nitric-oxide synthase inhibitors is solely determined by their affinity toward the different isoenzymes. , 2000, Molecular pharmacology.

[13]  M. Hengartner.  The biochemistry of apoptosis , 2000, Nature.

[14]  A. Zeiher,et al.  Nitric Oxide Down-regulates MKP-3 mRNA Levels , 2000, The Journal of Biological Chemistry.

[15]  B. Freeman,et al.  Concentration-dependent Effects of Nitric Oxide on Mitochondrial Permeability Transition and Cytochrome cRelease* , 2000, The Journal of Biological Chemistry.

[16]  J. Kleeff,et al.  Actinomycin D induces apoptosis and inhibits growth of pancreatic cancer cells , 2000, International journal of cancer.

[17]  M. Knaapen,et al.  The role of apoptosis in vascular disease , 2000, The Journal of pathology.

[18]  J. Laplanche,et al.  Annexin V delays apoptosis while exerting an external constraint preventing the release of CD4+ and PrPc+ membrane particles in a human T lymphocyte model. , 1999, Journal of immunology.

[19]  T. Billiar,et al.  Nitric oxide as a bifunctional regulator of apoptosis. , 1999, Circulation research.

[20]  R. Andriantsitohaina,et al.  Natural dietary polyphenolic compounds cause endothelium-dependent vasorelaxation in rat thoracic aorta. , 1998, The Journal of nutrition.

[21]  Y. Lazebnik,et al.  Caspases: enemies within. , 1998, Science.

[22]  A. Roulston,et al.  Early Activation of c-Jun N-terminal Kinase and p38 Kinase Regulate Cell Survival in Response to Tumor Necrosis Factor α* , 1998, The Journal of Biological Chemistry.

[23]  T. Billiar,et al.  Nitric Oxide Inhibits Apoptosis by Preventing Increases in Caspase-3-like Activity via Two Distinct Mechanisms* , 1997, The Journal of Biological Chemistry.

[24]  J. Rutledge,et al.  Nitric Oxide Mediates LDL Uptake in the Artery Wall in Response to High Concentrations of 17β-Estradiol , 1997 .

[25]  T. Billiar,et al.  Adenoviral transfer of the inducible nitric oxide synthase gene blocks endothelial cell apoptosis. , 1997, Surgery.

[26]  R. Andriantsitohaina,et al.  Nitric oxide production and endothelium‐dependent vasorelaxation induced by wine polyphenols in rat aorta , 1997, British journal of pharmacology.

[27]  M. Nehls,et al.  Suppression of Apoptosis by Nitric Oxide via Inhibition of Interleukin-1β–converting Enzyme (ICE)-like and Cysteine Protease Protein (CPP)-32–like Proteases , 1997, The Journal of experimental medicine.

[28]  J. Freyssinet,et al.  Oyxsterols induce membrane procoagulant activity in monocytic THP-1 cells. , 1996, The Biochemical journal.

[29]  Michael E. Greenberg,et al.  Opposing Effects of ERK and JNK-p38 MAP Kinases on Apoptosis , 1995, Science.

[30]  D. Harrison,et al.  Molecular regulation of the bovine endothelial cell nitric oxide synthase by transforming growth factor-beta 1. , 1995, Arteriosclerosis, thrombosis, and vascular biology.

[31]  M. Díaz-Guerra,et al.  Bacterial Lipopeptides Induce Nitric Oxide Synthase and Promote Apoptosis through Nitric Oxide-independent Pathways in Rat Macrophages (*) , 1995, The Journal of Biological Chemistry.

[32]  J. Stamler,et al.  Nitric oxide produced by human B lymphocytes inhibits apoptosis and Epstein-Barr virus reactivation , 1994, Cell.

[33]  E. Feskens,et al.  Dietary antioxidant flavonoids and risk of coronary heart disease: the Zutphen Elderly Study , 1993, The Lancet.

[34]  R. Miller,et al.  Morphological characterization of cultured bovine aortic endothelial cells and the effects of atriopeptin II and sodium nitroprusside on cellular and extracellular accumulation of cyclic GMP. , 1988, European journal of cell biology.

[35]  J. Rutledge,et al.  Nitric oxide mediates LDL uptake in the artery wall in response to high concentrations of 17 beta-estradiol. , 1997, Arteriosclerosis, thrombosis, and vascular biology.

[36]  R. Furchgott,et al.  Endothelium-dependent responses: the last three years. , 1984, Bibliotheca cardiologica.

[37]  L. Eisenman.  Organization of the olivocerebellar projection to the uvula in the rat. , 1984, Brain, behavior and evolution.

[38]  J. Kühnau.  The flavonoids. A class of semi-essential food components: their role in human nutrition. , 1976, World review of nutrition and dietetics.