A dissertation for the degree of Doctor of Philosophy

·······································································i CONTENTS······································································iii LIST OF FIGURES·························································· vii LIST OF ABBREVIATIONS··············································ix GENERAL INTRODUCTION············································1 Chapter I. Adipose stem cells and cancer······································3 Chapter II. Cancer stem cells and chemoresistance·························7 CHAPTER I·····································································12 Adipose stem cells from visceral and subcutaneous fat depots enhance growth and migration of ovarian cancer cells via activation of IL-6/JAK2/STAT3 pathway Abstract············································································13···········································································13 Introduction·······································································14 Materials and Methods························································· 15 Isolation of CD45/CD31 ASCs··········································16 Culture of ASCs and ovarian cancer cells·······························17

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