Crystal structure of Staphylococcus aureus tyrosyl‐tRNA synthetase in complex with a class of potent and specific inhibitors
暂无分享,去创建一个
Xiayang Qiu | Paul Carter | Judith M. LaLonde | C. Janson | P. Carter | S. Green | A. Fosberry | Ward W. Smith | K. Johanson | X. Qiu | P. Mcdevitt | C. Lewis | Cheryl A. Janson | Ward W. Smith | Susan M. Green | Patrick McDevitt | Kyung Johanson | Martin Hibbs | Ceri Lewis | Alison Chalker | Andrew Fosberry | Judith Lalonde | John Berge | Pamela Brown | Catherine S.V. Houge‐Frydrych | Richard L. Jarvest | P. Brown | M. Hibbs | R. L. Jarvest | A. Chalker | J. Berge | C. S. Houge-Frydrych
[1] A. Pope,et al. Synthetic analogues of SB-219383. Novel C-glycosyl peptides as inhibitors of tyrosyl tRNA synthetase. , 2001, Bioorganic & medicinal chemistry letters.
[2] A. Pope,et al. Potent synthetic inhibitors of tyrosyl tRNA synthetase derived from C-pyranosyl analogues of SB-219383. , 2001, Bioorganic & medicinal chemistry letters.
[3] A. Pope,et al. Synthesis and activity of analogues of SB-219383: novel potent inhibitors of bacterial tyrosyl tRNA synthetase. , 2000, The Journal of antibiotics.
[4] A. Pope,et al. Inhibitors of bacterial tyrosyl tRNA synthetase: synthesis of four stereoisomeric analogues of the natural product SB-219383. , 2000, Bioorganic & medicinal chemistry letters.
[5] S. Ready,et al. SB-219383, a novel tyrosyl tRNA synthetase inhibitor from a Micromonospora sp. I. Fermentation, isolation and properties. , 2000, The Journal of antibiotics.
[6] S. Readshaw,et al. SB-219383, a novel tyrosyl tRNA synthetase inhibitor from a Micromonospora sp. II. Structure determination. , 2000, The Journal of antibiotics.
[7] N. F. Osborne,et al. Molecular recognition of tyrosinyl adenylate analogues by prokaryotic tyrosyl tRNA synthetases. , 1999, Bioorganic & medicinal chemistry.
[8] J Hill,et al. Aminoacyl tRNA synthetases as targets for new anti‐infectives , 1998, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[9] R J Read,et al. Crystallography & NMR system: A new software suite for macromolecular structure determination. , 1998, Acta crystallographica. Section D, Biological crystallography.
[10] Eric A. First,et al. Human Tyrosyl-tRNA Synthetase Shares Amino Acid Sequence Homology with a Putative Cytokine* , 1997, The Journal of Biological Chemistry.
[11] I. Hudson,et al. The efficacy of intranasal mupirocin in the prevention of staphylococcal infections: a review of recent experience. , 1994, The Journal of hospital infection.
[12] D. McRee. Practical Protein Crystallography , 1993 .
[13] Axel T. Brunger,et al. X-PLOR Version 3.1: A System for X-ray Crystallography and NMR , 1992 .
[14] Olivier Poch,et al. Partition of tRNA synthetases into two classes based on mutually exclusive sets of sequence motifs , 1990, Nature.
[15] P. Brick,et al. Structure of tyrosyl-tRNA synthetase refined at 2.3 A resolution. Interaction of the enzyme with the tyrosyl adenylate intermediate. , 1989, Journal of molecular biology.
[16] A. Fersht,et al. Reconstruction by site-directed mutagenesis of the transition state for the activation of tyrosine by the tyrosyl-tRNA synthetase: a mobile loop envelopes the transition state in an induced-fit mechanism. , 1988, Biochemistry.
[17] P. Brick,et al. Crystal structure of a deletion mutant of a tyrosyl-tRNA synthetase complexed with tyrosine. , 1987, Journal of molecular biology.
[18] P. Brick,et al. Structure of a mutant of tyrosyl-tRNA synthetase with enhanced catalytic properties , 1987, Nature.
[19] A. Fersht,et al. Transition-state stabilization in the mechanism of tyrosyl-tRNA synthetase revealed by protein engineering. , 1985, Proceedings of the National Academy of Sciences of the United States of America.
[20] S. Blackburn,et al. Enzyme structure and function , 1976 .
[21] A. Fersht. Demonstration of two active sites on a monomeric aminoacyl-tRNA synthetase. Possible roles of negative cooperativity and half-of-the-sites reactivity in oligomeric enzymes. , 1975, Biochemistry.
[22] D. Blow,et al. Letter: Crystallization and preliminary x-ray diffraction studies on tyrosyl-transfer RNA synthetase from Bacillus stearothermophilus. , 1973, Journal of molecular biology.