An overview of systematic reviews of the effectiveness of opiate maintenance therapies: available evidence to inform clinical practice and research.

[1]  R P Mattick,et al.  Methadone maintenance therapy versus no opioid replacement therapy for opioid dependence. , 2009, The Cochrane database of systematic reviews.

[2]  Laura Amato,et al.  Effectiveness of interventions on opiate withdrawal treatment: an overview of systematic reviews. , 2004, Drug and alcohol dependence.

[3]  W. van den Brink,et al.  Medical prescription of heroin to treatment resistant heroin addicts: two randomised controlled trials , 2003, BMJ : British Medical Journal.

[4]  F. Faggiano,et al.  Methadone maintenance at different dosages for opioid dependence. , 2003, The Cochrane database of systematic reviews.

[5]  M. Ferri,et al.  Heroin maintenance for chronic heroin dependents. , 2003, The Cochrane database of systematic reviews.

[6]  W. Hall,et al.  Heroin overdose: Research and evidence-based intervention , 2003, Journal of Urban Health.

[7]  J. Strang,et al.  Loss of tolerance and overdose mortality after inpatient opiate detoxification: follow up study , 2003, BMJ : British Medical Journal.

[8]  R. Mattick,et al.  Methadone-related and heroin-related deaths among opiate users: methadone helps save lives. , 2003, Addiction.

[9]  Jason M. White,et al.  Buprenorphine versus methadone maintenance therapy: a randomized double-blind trial with 405 opioid-dependent patients. , 2003, Addiction.

[10]  P. Elliott,et al.  Trends in drug overdose deaths in England and Wales 1993-98: methadone does not kill more people than heroin. , 2003, Addiction.

[11]  S. Bird,et al.  Male drugs-related deaths in the fortnight after release from prison: Scotland, 1996-99. , 2003, Addiction.

[12]  P. Oliver,et al.  Concomitant drugs of misuse and drug using behaviours associated with fatal opiate-related poisonings in Sheffield, UK, 1997-2000. , 2003, Addiction.

[13]  R. Ali,et al.  Relationship between LAAM-methadone preference and treatment outcomes. , 2002, Drug and alcohol dependence.

[14]  A. Ritter,et al.  LAAM maintenance vs methadone maintenance for heroin dependence. , 2002, The Cochrane database of systematic reviews.

[15]  F. Forastiere,et al.  Mortality among problem drug users in Rome: an 18-year follow-up study, 1980-97. , 2001, Addiction.

[16]  J. Marsden,et al.  Outcomes after methadone maintenance and methadone reduction treatments: two-year follow-up results from the National Treatment Outcome Research Study. , 2001, Drug and alcohol dependence.

[17]  R. Stohler,et al.  Double-blind randomized trial of buprenorphine and methadone in opiate dependence. , 2001, Drug and alcohol dependence.

[18]  A T McLellan,et al.  Drug dependence, a chronic medical illness: implications for treatment, insurance, and outcomes evaluation. , 2000, JAMA.

[19]  M. Ferri,et al.  The Cochrane Review Group on Drugs and Alcohol. , 2000, Addiction.

[20]  G. Gessa,et al.  Buprenorphine: a controlled clinical trial in the treatment of opioid dependence. , 2000, Drug and alcohol dependence.

[21]  D. Epstein,et al.  Methadone dose increase and abstinence reinforcement for treatment of continued heroin use during methadone maintenance. , 2000, Archives of general psychiatry.

[22]  R. Jagsch,et al.  Buprenorphine versus methadone maintenance for the treatment of opioid dependence , 1999, European Neuropsychopharmacology.

[23]  S. Kasper,et al.  Buprenorphine versus methadone maintenance for the treatment of opioid dependence. , 1999 .

[24]  M. Langendam,et al.  Dose-effect relationship between overdose mortality and prescribed methadone dosage in low-threshold maintenance programs. , 1999, Addictive behaviors.

[25]  K. Sporer.  Acute Heroin Overdose , 1999, Annals of Internal Medicine.

[26]  M. Stitzer,et al.  Moderate- vs high-dose methadone in the treatment of opioid dependence: a randomized trial. , 1999, JAMA.

[27]  D. English,et al.  The quantification of mortality resulting from the regular use of illicit opiates. , 1999, Addiction.

[28]  Jeff Ward,et al.  Role of maintenance treatment in opioid dependence , 1999, The Lancet.

[29]  M. Gaughwin,et al.  Correlates of retention on the South Australian Methadone Program 1981–91 , 1998, Australian and New Zealand journal of public health.

[30]  M. Davoli,et al.  Retention in treatment of heroin users in Italy: the role of treatment type and of methadone maintenance dosage. , 1998, Drug and alcohol dependence.

[31]  D. Ladewig,et al.  Comparison of Buprenorphine and Methadone in the Treatment of Opioid Dependence , 1998, European Addiction Research.

[32]  P. Reuter.  World drug report , 1998 .

[33]  T. Perneger,et al.  Randomised trial of heroin maintenance programme for addicts who fail in conventional drug treatments , 1998, BMJ.

[34]  A. Leshner.  Drug addiction research: moving toward the 21st century. , 1998, Drug and alcohol dependence.

[35]  W. Ling,et al.  Buprenorphine maintenance treatment of opiate dependence: a multicenter, randomized clinical trial. , 1998, Addiction.

[36]  C. O'brien,et al.  A range of research-based pharmacotherapies for addiction. , 1997, Science.

[37]  T. Perneger,et al.  Predictors of patient retention in a newly established methadone maintenance treatment programme. , 1997, Addiction.

[38]  D. Ziedonis,et al.  Buprenorphine vs methadone maintenance treatment for concurrent opioid dependence and cocaine abuse. , 1997, Archives of general psychiatry.

[39]  J. F. Maddux,et al.  The relationship of methadone dose and other variables to outcomes of methadone maintenance. , 1997, The American journal on addictions.

[40]  F. Forastiere,et al.  A persistent rise in mortality among injection drug users in Rome, 1980 through 1992. , 1997, American journal of public health.

[41]  Donald F. Dansereau,et al.  Strategies for Improving Methadone Treatment Process and Outcomes , 1997 .

[42]  M. Rahman,et al.  Mortality and survival among a cohort of drug injectors in Glasgow, 1982-1994. , 1997, Addiction.

[43]  J. Antó,et al.  Mortality trends in a cohort of opiate addicts, Catalonia, Spain. , 1996, International journal of epidemiology.

[44]  W. Hall.  Methadone Maintenance Treatment as a Crime Control Measure , 1996 .

[45]  W. Hall,et al.  Methadone maintenance reduces injecting in prison , 1996, BMJ.

[46]  W. Ling,et al.  A controlled trial comparing buprenorphine and methadone maintenance in opioid dependence. , 1996, Archives of general psychiatry.

[47]  M. Torrens,et al.  Retention in a low-threshold methadone maintenance program. , 1996, Drug and alcohol dependence.

[48]  A. Goldstein,et al.  Heroin addicts and methadone treatment in Albuquerque: a 22-year follow-up. , 1995, Drug and alcohol dependence.

[49]  M. Stitzer,et al.  A placebo controlled clinical trial of buprenorphine as a treatment for opioid dependence. , 1995, Drug and alcohol dependence.

[50]  G. Barrio,et al.  Opiates or cocaine: mortality from acute reactions in six major Spanish cities. State Information System on Drug Abuse (SEIT) Working Group. , 1995, Journal of epidemiology and community health.

[51]  M. Stitzer,et al.  Buprenorphine versus methadone in the treatment of opioid-dependent cocaine users , 1994, Psychopharmacology.

[52]  D. D. Des Jarlais,et al.  Fortnightly Review: Methadone maintenance treatment in opiate dependence: a review , 1994 .

[53]  J. Caplehorn,et al.  Retention in methadone maintenance and heroin addicts' risk of death. , 1994, Addiction.

[54]  M. Stitzer,et al.  Dose-Response Effects of Methadone in the Treatment of Opioid Dependence , 1993, Annals of Internal Medicine.

[55]  K. Powers,et al.  A 24-year follow-up of California narcotics addicts. , 1993, Archives of general psychiatry.

[56]  D. Ziedonis,et al.  Buprenorphine versus Methadone Maintenance for Opioid Dependence , 1993, The Journal of nervous and mental disease.

[57]  J. Jaffe,et al.  A controlled trial of buprenorphine treatment for opioid dependence. , 1992, JAMA.

[58]  A. Dinnen.  Methadone dosage and retention of patients in maintenance treatment , 1991, The Medical journal of Australia.

[59]  R. Brettle.  HIV and harm reduction for injection drug users. , 1991, AIDS.

[60]  P. W. Jepsen,et al.  Seven year follow‐up of 300 young drug abusers , 1984, Acta psychiatrica Scandinavica.

[61]  R. Doll.  The controlled trial. , 1984, Postgraduate medical journal.

[62]  A. Washton,et al.  LAAM instead of take-home methadone. , 1982, NIDA research monograph.

[63]  R. Freedman,et al.  A comparison of thrice weekly LAAM and daily methadone in employed heroin addicts. , 1981, Drug and alcohol dependence.

[64]  L. Grönbladh,et al.  The Swedish methadone maintenance program: a controlled study. , 1981, Drug and alcohol dependence.

[65]  C. O'brien,et al.  A clinical, controlled study of l-alpha-acetylmethadol in the treatment of narcotic addiction. , 1981, The American journal of psychiatry.

[66]  R. Hartnoll,et al.  Evaluation of heroin maintenance in controlled trial. , 1980, Archives of general psychiatry.

[67]  R. Newman,et al.  DOUBLE-BLIND COMPARISON OF METHADONE AND PLACEBO MAINTENANCE TREATMENTS OF NARCOTIC ADDICTS IN HONG KONG , 1979, The Lancet.

[68]  C. Klett,et al.  A cooperative clinical study of methadyl acetate. I. Three-times-a-week regimen. , 1978, Archives of general psychiatry.

[69]  A. Goldstein,et al.  Failure of methadone and levomethadyl acetate (levo-alpha-acetylmethadol, LAAM) maintenance to affect memory. , 1977, Archives of general psychiatry.

[70]  P. Renault,et al.  Methadyl acetate and methadone. An open comparison. , 1977, JAMA.

[71]  J. Jaffe,et al.  A 48-week study of methadone, methadyl acetate, and minimal services. 1974 [proceedings]. , 1976, NIDA research monograph.

[72]  P. Blachly,et al.  The behavioral, cognitive and physiologic effects of long-term methadone and methadyl treatment. 1973 [proceedings]. , 1976, NIDA research monograph.

[73]  C. Klett,et al.  Methadyl acetate and methadone as maintenance treatments for heroin addicts. A veterans administration cooperative study. , 1976, Archives of general psychiatry.

[74]  E. Karp,et al.  Methadone/LAAM maintenance: a comparison study. , 1976, Comprehensive psychiatry.

[75]  A. Freedman,et al.  Levomethadyl in maintenance treatment of opiate dependence. , 1972, JAMA.

[76]  C. O. Kennedy.  A controlled trial , 1971, British Homeopathic Journal.

[77]  E. Caine,et al.  Methadone treatment of randomly selected criminal addicts. , 1969, The New England journal of medicine.

[78]  V. Dole,et al.  Heroin addiction--a metabolic disease. , 1967, Archives of internal medicine.

[79]  R P Mattick,et al.  Buprenorphine maintenance versus placebo or methadone maintenance for opioid dependence. , 2008, The Cochrane database of systematic reviews.

[80]  R. Mattick,et al.  Methadone maintenance therapy versus no opioid replacement therapy for opioid dependence. , 2003, The Cochrane database of systematic reviews.

[81]  S. Brissette.  Medical prescription of heroin--a review. , 2001, Canadian HIV/AIDS policy & law review.

[82]  Eorge,et al.  A COMPARISON OF LEVOMETHADYL ACETATE , BUPRENORPHINE , AND METHADONE FOR OPIOID DEPENDENCE , 2000 .

[83]  J. Schmitz,et al.  Retention, HIV risk, and illicit drug use during treatment: methadone dose and visit frequency. , 1998, American journal of public health.

[84]  L. Irwig,et al.  Physicians' attitudes and retention of patients in their methadone maintenance programs. , 1996, Substance use & misuse.

[85]  D. D. Des Jarlais,et al.  A randomized trial of an interim methadone maintenance clinic. , 1991, American journal of public health.

[86]  K. Choopanya,et al.  A controlled trial of methadone maintenance in a population of intravenous drug users in Bangkok: implications for prevention of HIV. , 1991, The International journal of the addictions.

[87]  O. McCabe,et al.  Evaluation of clinic attendance schedules for LAAM and methadone: a controlled study. , 1982, The International journal of the addictions.

[88]  W. X. Lehmann.  The use of 1-alpha-acetyl-methadol (LAAM) as compared to methadone in the maintenance and detoxification of young heroin addicts. 1973 [proceedings]. , 1976, NIDA research monograph.

[89]  A. Goldstein,et al.  Proceedings: Efficacy and side effects of three widely different methadone doses. , 1973, Proceedings. National Conference on Methadone Treatment.