Ulnar neuropathy at the elbow: Five new things.

Ulnar neuropathy at the elbow (UNE) is the second most frequent compression neuropathy. While other diagnostic imaging tools are emerging to assist in the diagnosis of UNE, electrodiagnosis remains the gold standard. However, the electrodiagnostic approach to UNE presents unique challenges limiting its diagnostic accuracy. We review advances in 5 areas relevant to the diagnosis of UNE: technologic advancements with modern EMG machines have allowed for reconsideration of the question of experimental error and lesion detection; how temperature effects can lead to misdiagnosis; the effect of body mass index on the electrodiagnosis of UNE; the validation of short segment studies; and the emerging role of high-resolution sonography as a diagnostic tool.

[1]  Max Wintermark,et al.  Magnetic resonance-guided focused ultrasound surgery: Part 2: A review of current and future applications. , 2012, Neurosurgery.

[2]  A. Vincent,et al.  Morvan syndrome: Clinical and serological observations in 29 cases , 2012, Annals of neurology.

[3]  P. Mailly,et al.  Microtubule-targeting drugs rescue axonal swellings in cortical neurons from spastin knockout mice , 2012, Disease Models & Mechanisms.

[4]  C. Blackstone,et al.  Cellular pathways of hereditary spastic paraplegia. , 2012, Annual review of neuroscience.

[5]  Z. Wszolek,et al.  Genotype-phenotype correlations in THAP1 dystonia: molecular foundations and description of new cases. , 2012, Parkinsonism & related disorders.

[6]  A. Vincent,et al.  The expanding spectrum of clinically-distinctive, immunotherapy-responsive autoimmune encephalopathies. , 2012, Arquivos de neuro-psiquiatria.

[7]  D. Maraganore,et al.  Mutations in CIZ1 cause adult onset primary cervical dystonia , 2012, Annals of neurology.

[8]  Paul S. Larson,et al.  An Optimized System for Interventional Magnetic Resonance Imaging-Guided Stereotactic Surgery: Preliminary Evaluation of Targeting Accuracy , 2012, Neurosurgery.

[9]  M. Okun,et al.  Variant ataxia-telangiectasia presenting as primary-appearing dystonia in Canadian Mennonites , 2012, Neurology.

[10]  James N. Hughes,et al.  PRRT2 mutations cause benign familial infantile epilepsy and infantile convulsions with choreoathetosis syndrome. , 2012, American journal of human genetics.

[11]  Ning Wang,et al.  Exome sequencing identifies truncating mutations in PRRT2 that cause paroxysmal kinesigenic dyskinesia , 2011, Nature Genetics.

[12]  K. Xia,et al.  Identification of PRRT2 as the causative gene of paroxysmal kinesigenic dyskinesias , 2011, Brain : a journal of neurology.

[13]  Alberto Luini,et al.  Mendelian disorders of membrane trafficking. , 2011, The New England journal of medicine.

[14]  J. Dalmau,et al.  Movement disorders in paraneoplastic and autoimmune disease. , 2011, Current opinion in neurology.

[15]  K. Herrup,et al.  Stable Brain ATM Message and Residual Kinase-Active ATM Protein in Ataxia-Telangiectasia , 2011, The Journal of Neuroscience.

[16]  W. Verhagen,et al.  Ultrasonography in ulnar neuropathy at the elbow: A critical review , 2011, Muscle & nerve.

[17]  J. Schott,et al.  Faciobrachial dystonic seizures precede Lgi1 antibody limbic encephalitis , 2011, Annals of neurology.

[18]  Richard Robinson DaTscan Approved for Dopamine Transporter Imaging; Skeptics Doubt Clinical Value , 2011 .

[19]  Stephanie Stephens,et al.  Essential Facts about Essential Tremor: This “quiet” disease, which affects 10 million Americans, is anything but benign. , 2011 .

[20]  R. Balice-Gordon,et al.  Clinical experience and laboratory investigations in patients with anti-NMDAR encephalitis , 2011, The Lancet Neurology.

[21]  T. Farley Playing His Hand: After being diagnosed with focal dystonia of his right hand, professional musician Billy McLaughlin relearned how to play the guitar—with his left. , 2010 .

[22]  R. Young,et al.  Gamma Knife thalamotomy for treatment of essential tremor: long-term results. , 2010, Journal of neurosurgery.

[23]  E. Moro,et al.  Gamma knife thalamotomy for disabling tremor: a blinded evaluation. , 2010, Archives of neurology.

[24]  Katsuhito Yasuno,et al.  Reduced neuron-specific expression of the TAF1 gene is associated with X-linked dystonia-parkinsonism. , 2007, American journal of human genetics.

[25]  M. Landau,et al.  Cold elbow syndrome: Spurious slowing of ulnar nerve conduction velocity , 2005, Muscle & nerve.

[26]  M. Landau,et al.  Effect of body mass index on ulnar nerve conduction velocity, ulnar neuropathy at the elbow, and carpal tunnel syndrome , 2005, Muscle & nerve.

[27]  R. Prinz,et al.  Axonal and extracellular matrix responses to experimental chronic nerve entrapment , 2005, Brain Research.

[28]  H. Franssen,et al.  Short‐segment nerve conduction studies in ulnar neuropathy at the elbow , 2005, Muscle & nerve.

[29]  M. Landau,et al.  Optimal screening distance for ulnar neuropathy at the elbow , 2003, Muscle & nerve.

[30]  M. Landau,et al.  Optimal distance for segmental nerve conduction studies revisited , 2003, Muscle & nerve.

[31]  R. Lovelace,et al.  The utility of segmental nerve conduction studies in ulnar mononeuropathy at the elbow , 2003, Muscle & nerve.

[32]  M. Zwarts,et al.  What is the best way to assess focal slowing of the ulnar nerve? , 2001, Clinical Neurophysiology.

[33]  W. Campbell,et al.  Short segment incremental studies in the evaluation of ulnar neuropathy at the elbow , 1992, Muscle & nerve.

[34]  C. Hong,et al.  Peroneal Nerve Entrapment at the Knee Localized by Short Segment Stimulation , 1989, American journal of physical medicine & rehabilitation.

[35]  Simons Dg,et al.  Ulnar nerve entrapment at the elbow localized by short segment stimulation. , 1988 .

[36]  W. Campbell,et al.  Intraoperative electroneurography: Management of ulnar neuropathy at the elbow , 1988, Muscle & nerve.

[37]  Robert G. Miller,et al.  The cubital tunnel syndrome: Diagnosis and precise localization , 1979, Annals of neurology.

[38]  W. Brown,et al.  The Location of Conduction Abnormalities in Human Entrapment Neuropathies , 1976, Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques.

[39]  Stolov Wc,et al.  Experimental error in determination of nerve conduction velocity. , 1972 .

[40]  H. Kaeser [CONDUCTION DISORDERS IN ULNAR NERVE PARALYSIS]. , 1963, Deutsche Zeitschrift fur Nervenheilkunde.

[41]  Campbell Ww Guidelines in electrodiagnostic medicine. Practice parameter for electrodiagnostic studies in ulnar neuropathy at the elbow. , 1999, Muscle & nerve. Supplement.

[42]  W. Campbell,et al.  Guidelines in electrodiagnostic medicine. Practice parameter for electrodiagnostic studies in ulnar neuropathy at the elbow. , 1999, Muscle & nerve. Supplement.

[43]  R. Zucker,et al.  Ulnar nerve entrapment at the elbow localized by short segment stimulation. , 1988, Archives of physical medicine and rehabilitation.

[44]  J Kimura,et al.  The carpal tunnel syndrome: localization of conduction abnormalities within the distal segment of the median nerve. , 1979, Brain : a journal of neurology.

[45]  F. Maynard,et al.  Experimental error in determination of nerve conduction velocity. , 1972, Archives of physical medicine and rehabilitation.