Candidal abscess of the parotid gland due to Candida glabrata: report of a case and literature review.

We report the case of an immunocompetent woman who developed a Candida glabrata abscess of the parotid gland and present a review of similar cases from the literature. Diagnosis was based on the isolation of C. glabrata in pure culture from the abscess pus. Examination of stained smears of the same material demonstrated small sized yeast cells, some being intra-macrophagic. Combination of a local drainage and oral fluconazole proved to be an efficient therapeutic strategy. Candidal abscesses are rare in immunocompetent patients and salivary gland localization has only been reported in five cases.

[1]  I. Kaplan,et al.  Major salivary gland output differs between users and non-users of specific medication categories. , 2008, Gerodontology.

[2]  I. Beyer,et al.  Denture contamination by yeasts in the elderly. , 2008, Gerodontology.

[3]  Tuğba Taşkin,et al.  Cryptococcal parotid involvement: an uncommon localization of Cryptococcus neoformans. , 2006, Medical mycology.

[4]  Ella Even-Tov,et al.  Candida parotitis with abscess formation , 2006, Acta oto-laryngologica.

[5]  T. Tollefson,et al.  Cryptococcal parotitis presenting as a cystic parotid mass: Report of a case diagnosed by fine‐needle aspiration cytology , 2005, Diagnostic cytopathology.

[6]  Panagiotis K. Stefanopoulos,et al.  Stensen’s duct obstruction by foreign body and subsequent candidal infection of the parotid gland , 2003, The Journal of Laryngology & Otology.

[7]  A. Staffieri,et al.  Candidal Abscess of the Parotid Gland Associated with Facial Nerve Paralysis , 2003, Acta oto-laryngologica.

[8]  G. Böhm,et al.  Parotid gland involvement in advanced AIDS. , 2003, Oral diseases.

[9]  I. Brook Acute Bacterial Suppurative Parotitis: Microbiology and Management , 2003, The Journal of craniofacial surgery.

[10]  J. Beijnen,et al.  Can Fluconazole Concentrations in Saliva Be Used for Therapeutic Drug Monitoring? , 2001, Therapeutic drug monitoring.

[11]  A. Francesconi,et al.  Dosage-Dependent Antifungal Efficacy of V-Echinocandin (LY303366) against Experimental Fluconazole-Resistant Oropharyngeal and Esophageal Candidiasis , 2001, Antimicrobial Agents and Chemotherapy.

[12]  M. Edgerton,et al.  Salivary Histatin 5 and its Similarities to the Other Antimicrobial Proteins in Human Saliva , 2000, Advances in dental research.

[13]  B. Pachter,et al.  Parotitis due to Torulopsis glabrata. , 1995, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

[14]  C. Scully,et al.  Mucocutaneous histoplasmosis in AIDS , 1995, The British journal of dermatology.

[15]  M. Cohen,et al.  Fine‐needle aspiration biopsy of salivary gland mycoses , 1994, Diagnostic cytopathology.