OCTN2VT, a splice variant of OCTN2, does not transport carnitine because of the retention in the endoplasmic reticulum caused by insertion of 24 amino acids in the first extracellular loop of OCTN2.

[1]  E. Burchard,et al.  Functional Genetic Diversity in the High-Affinity Carnitine Transporter OCTN2 (SLC22A5) , 2006, Molecular Pharmacology.

[2]  Guangping Chen,et al.  Loss of N-Linked Glycosylation Reduces Urea Transporter UT-A1 Response to Vasopressin* , 2006, Journal of Biological Chemistry.

[3]  K. Nagai,et al.  Cloning and functional characterization of a novel up-regulator, cartregulin, of carnitine transporter, OCTN2. , 2006, Archives of biochemistry and biophysics.

[4]  N. Longo,et al.  Pharmacological rescue of carnitine transport in primary carnitine deficiency , 2006, Human mutation.

[5]  A. DeFranco,et al.  TLR3 and TLR7 Are Targeted to the Same Intracellular Compartments by Distinct Regulatory Elements*♦ , 2005, Journal of Biological Chemistry.

[6]  A. DeFranco,et al.  Ligand-regulated Chimeric Receptor Approach Reveals Distinctive Subcellular Localization and Signaling Properties of the Toll-like Receptors* , 2004, Journal of Biological Chemistry.

[7]  N. Longo,et al.  Tyrosine Residues Affecting Sodium Stimulation of Carnitine Transport in the OCTN2 Carnitine/Organic Cation Transporter* , 2004, Journal of Biological Chemistry.

[8]  S. Eaton,et al.  Mitochondrial beta-oxidation. , 2004, European journal of biochemistry.

[9]  K. Jarvi,et al.  Characterization of organic cation/carnitine transporter family in human sperm. , 2003, Biochemical and biophysical research communications.

[10]  S. Scherer,et al.  A third human carnitine/organic cation transporter (OCTN3) as a candidate for the 5q31 Crohn's disease locus (IBD5). , 2003, Biochemical and biophysical research communications.

[11]  G. Mitchell,et al.  Carnitine transport by organic cation transporters and systemic carnitine deficiency. , 2001, Molecular genetics and metabolism.

[12]  A. Helenius,et al.  Intracellular functions of N-linked glycans. , 2001, Science.

[13]  J. Nezu,et al.  Molecular and physiological evidence for multifunctionality of carnitine/organic cation transporter OCTN2. , 2001, Molecular pharmacology.

[14]  J. Nezu,et al.  Molecular and Functional Characterization of Organic Cation/Carnitine Transporter Family in Mice* , 2000, The Journal of Biological Chemistry.

[15]  N. Longo,et al.  Abnormal Sodium Stimulation of Carnitine Transport in Primary Carnitine Deficiency* , 2000, The Journal of Biological Chemistry.

[16]  K. Irie,et al.  TAB2, a novel adaptor protein, mediates activation of TAK1 MAPKKK by linking TAK1 to TRAF6 in the IL-1 signal transduction pathway. , 2000, Molecular cell.

[17]  V. Ganapathy,et al.  Mutations in Novel Organic Cation Transporter (OCTN2), an Organic Cation/Carnitine Transporter, with Differential Effects on the Organic Cation Transport Function and the Carnitine Transport Function* , 1999, The Journal of Biological Chemistry.

[18]  N. Longo,et al.  Mutations in the organic cation/carnitine transporter OCTN2 in primary carnitine deficiency. , 1999, Proceedings of the National Academy of Sciences of the United States of America.

[19]  J. Nezu,et al.  Molecular and Functional Identification of Sodium Ion-dependent, High Affinity Human Carnitine Transporter OCTN2* , 1998, The Journal of Biological Chemistry.

[20]  T. Uehara,et al.  Activation of Stat1 and subsequent transcription of inducible nitric oxide synthase gene in C6 glioma cells is independent of interferon‐γ‐induced MAPK activation that is mediated by p21 ras , 1997, FEBS letters.

[21]  G. Tsujimoto,et al.  Primary systemic carnitine deficiency is caused by mutations in a gene encoding sodium ion-dependent carnitine transporter , 1999, Nature Genetics.

[22]  P. Sharp,et al.  Splicing of messenger RNA precursors. , 1987, Science.

[23]  P. Sharp,et al.  Splicing of messenger RNA precursors. , 1985, Harvey lectures.