Optical properties of human skin, subcutaneous and mucous tissues in the wavelength range from 400 to 2000 nm

The optical properties of human skin, subcutaneous adipose tissue and human mucosa were measured in the wavelength range 400–2000 nm. The measurements were carried out using a commercially available spectrophotometer with an integrating sphere. The inverse adding–doubling method was used to determine the absorption and reduced scattering coefficients from the measurements.

[1]  H. Claustre,et al.  Optical properties of the “clearest” natural waters , 2007 .

[2]  M. Poljački,et al.  Topical photodynamic therapy , 2006 .

[3]  Valery V. Tuchin,et al.  Immersion clearing of human blood in the visible and near-infrared spectral regions , 2005 .

[4]  Ton G van Leeuwen,et al.  Oxygen saturation-dependent absorption and scattering of blood. , 2004, Physical review letters.

[5]  R. deVere White,et al.  Spectroscopic detection of bladder cancer using near-infrared imaging techniques. , 2004, Journal of biomedical optics.

[6]  V. Tuchin,et al.  Low-intensity indocyanine-green laser phototherapy of acne vulgaris: pilot study. , 2004, Journal of biomedical optics.

[7]  P. Yamauchi,et al.  Topical photodynamic therapy in clinical dermatology , 2004, The British journal of dermatology.

[8]  M. Bentley,et al.  Photodynamic Therapy of Skin Cancers: Sensitizers, Clinical Studies and Future Directives , 2000, Pharmaceutical Research.

[9]  Valery V Tuchin,et al.  A pilot study of ICG laser therapy of acne vulgaris: Photodynamic and photothermolysis treatment , 2003, Lasers in surgery and medicine.

[10]  Sung K. Chang,et al.  Multispectral digital colposcopy for in vivo detection of cervical cancer. , 2003, Optics express.

[11]  Lars Nørgaard,et al.  Exploratory multivariate spectroscopic study on human skin , 2003, Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging.

[12]  William E. Vargas,et al.  Inversion methods from Kubelka–Munk analysis , 2002 .

[13]  M. Fehr,et al.  Photodynamic therapy of vulvar and vaginal condyloma and intraepithelial neoplasia using topically applied 5‐aminolevulinic acid * , 2002, Lasers in surgery and medicine.

[14]  S. Ibbotson,et al.  Topical 5‐aminolaevulinic acid photodynamic therapy for the treatment of skin conditions other than non‐melanoma skin cancer , 2002, The British journal of dermatology.

[15]  Brian W Pogue,et al.  Multispectral near-infrared tomography: a case study in compensating for water and lipid content in hemoglobin imaging of the breast. , 2002, Journal of biomedical optics.

[16]  H. Moseley,et al.  Laser and Non-laser Light Sources for Photodynamic Therapy , 2002, Lasers in Medical Science.

[17]  T. Tomaru,et al.  Vascular procedures that thermo‐coagulate collagen reduce local platelet deposition and thrombus formation: Laser and laser‐thermal versus balloon angioplasty , 2001, Lasers in surgery and medicine.

[18]  A Roggan,et al.  Optical properties of native and coagulated porcine liver tissue between 400 and 2400 nm , 2001, Lasers in surgery and medicine.

[19]  A. Oseroff,et al.  Laser and photodynamic therapy in the management of cutaneous malignancies. , 2001, Clinics in dermatology.

[20]  S. Thennadil,et al.  Optical properties of human skin in the near infrared wavelength range of 1000 to 2200 nm. , 2001, Journal of biomedical optics.

[21]  K. Langmack,et al.  Topical photodynamic therapy at low fluence rates--theory and practice. , 2001, Journal of photochemistry and photobiology. B, Biology.

[22]  Babak Nemati,et al.  Optical‐thermal simulation of tonsillar tissue irradiation , 2001, Lasers in surgery and medicine.

[23]  J Greenman,et al.  Killing of cutaneous microbial species by photodynamic therapy , 2001, The British journal of dermatology.

[24]  R. Glickman,et al.  Optical characterization of melanin. , 2000, Journal of biomedical optics.

[25]  Jun Q. Lu,et al.  Optical properties of porcine skin dermis between 900 nm and 1500 nm , 2001, Physics in medicine and biology.

[26]  S. Mohanty,et al.  Measurement of optical transport properties of normal and malignant human breast tissue. , 2001, Applied optics.

[27]  Valery V. Tuchin,et al.  Estimation of wavelength dependence of refractive index of collagen fibers of scleral tissue , 2000, European Conference on Biomedical Optics.

[28]  Valery V. Tuchin,et al.  In-vivo and in-vitro study of control of rat skin optical properties by action of osmotical liquid , 2000, Optics and Optoelectronic Inspection and Control.

[29]  R. Mason,et al.  Noninvasive investigation of blood oxygenation dynamics of tumors by near-infrared spectroscopy. , 2000, Applied optics.

[30]  D. Boas,et al.  Trans-abdominal monitoring of fetal arterial blood oxygenation using pulse oximetry. , 2000, Journal of biomedical optics.

[31]  W S Grundfest,et al.  Consequences of scattering for spectral imaging of turbid biologic tissue. , 2000, Journal of biomedical optics.

[32]  S. Lakhani,et al.  Diagnosis of breast cancer using elastic-scattering spectroscopy: preliminary clinical results. , 2000, Journal of biomedical optics.

[33]  A. Kleinschmidt,et al.  Noninvasive Functional Imaging of Human Brain Using Light , 2000, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[34]  Ruikang K. Wang.  Modelling optical properties of soft tissue by fractal distribution of scatterers , 2000 .

[35]  K Svanberg,et al.  Preliminary evaluation of two fluorescence imaging methods for the detection and the delineation of basal cell carcinomas of the skin , 2000, Lasers in surgery and medicine.

[36]  B Chance,et al.  Quantification of ischemic muscle deoxygenation by near infrared time-resolved spectroscopy. , 2000, Journal of biomedical optics.

[37]  P. Rehak,et al.  Hyperbaric oxygen and photodynamic therapy in the treatment of advanced carcinoma of the cardia and the esophagus , 2000, Lasers in surgery and medicine.

[38]  B A Buscher,et al.  Treatment of leg telangiectasia by using a long‐pulse dye laser at 595 nm with and without dynamic cooling device , 2000, Lasers in surgery and medicine.

[39]  V. Tuchin.  Tissue Optics: Light Scattering Methods and Instruments for Medical Diagnosis , 2000 .

[40]  S Y Shchyogolev,et al.  Inverse problems of spectroturbidimetry of biological disperse systems: an overview. , 1999, Journal of biomedical optics.

[41]  R. Doornbos,et al.  The determination of in vivo human tissue optical properties and absolute chromophore concentrations using spatially resolved steady-state diffuse reflectance spectroscopy. , 1999, Physics in medicine and biology.

[42]  H. G. Rylander,et al.  Use of an agent to reduce scattering in skin , 1999, Lasers in surgery and medicine.

[43]  W M Johnston,et al.  Optical properties of human trabecular meshwork in the visible and near‐infrared region , 1999, Lasers in surgery and medicine.

[44]  Joachim Mühling,et al.  Photodynamic therapy of primary nonmelanomatous skin tumours of the head and neck , 1999, Lasers in surgery and medicine.

[45]  H Stepp,et al.  Autofluorescence imaging and spectroscopy of normal and malignant mucosa in patients with head and neck cancer , 1999, Lasers in surgery and medicine.

[46]  A. Roggan,et al.  Optical Properties of Circulating Human Blood in the Wavelength Range 400-2500 nm. , 1999, Journal of biomedical optics.

[47]  Bruce J. Tromberg,et al.  In-vivo local determination of tissue optical properties , 1999, European Conference on Biomedical Optics.

[48]  M. Kohl,et al.  Near-infrared optical properties of ex vivo human skin and subcutaneous tissues measured using the Monte Carlo inversion technique. , 1998, Physics in medicine and biology.

[49]  W M Johnston,et al.  Articular Cartilage Optical Properties in the Spectral Range 300-850 nm. , 1998, Journal of biomedical optics.

[50]  J. Schmitt,et al.  Optical scattering properties of soft tissue: a discrete particle model. , 1998, Applied optics.

[51]  F F de Mul,et al.  Feasibility of picosecond laser-Doppler flowmetry provides basis for time-resolved Doppler tomography of biological tissues. , 1998, Journal of biomedical optics.

[52]  J. S. Dam,et al.  Determination of tissue optical properties from diffuse reflectance profiles by multivariate calibration. , 1998, Applied optics.

[53]  G K Krieglstein,et al.  Erbium:YAG laser trabecular ablation (LTA) in the surgical treatment of glaucoma , 1998, Lasers in surgery and medicine.

[54]  J W Pickering,et al.  In vitro double-integrating-sphere optical properties of tissues between 630 and 1064 nm , 1997, Physics in medicine and biology.

[55]  A. Young,et al.  Chromophores in human skin. , 1997, Physics in medicine and biology.

[56]  J. Mourant,et al.  Predictions and measurements of scattering and absorption over broad wavelength ranges in tissue phantoms. , 1997, Applied optics.

[57]  R. Anderson,et al.  Effects of heterogeneous absorption of laser radiation in biotissue ablation: Characterization of ablation of fat with a pulsed CO2 laser , 1997, Lasers in surgery and medicine.

[58]  J. Brunetaud,et al.  Lasers in digestive endoscopy. , 1997, Journal of biomedical optics.

[59]  P. Monnier,et al.  Light dosimetry for photodynamic therapy in the esophagus , 1997, Lasers in surgery and medicine.

[60]  Ashley J. Welch,et al.  Effects of compression on soft tissue optical properties , 1996 .

[61]  I. Yaroslavsky,et al.  Inverse hybrid technique for determining the optical properties of turbid media from integrating-sphere measurements. , 1996, Applied optics.

[62]  M Landthaler,et al.  Topical photodynamic therapy in dermatology. , 1996, Journal of photochemistry and photobiology. B, Biology.

[63]  H Koren,et al.  Photodynamic therapy in gynaecologic cancer. , 1996, Journal of photochemistry and photobiology. B, Biology.

[64]  B. Ortel,et al.  Photodynamic therapy with systemic administration of photosensitizers in dermatology. , 1996, Journal of photochemistry and photobiology. B, Biology.

[65]  F Calzavara,et al.  Photodynamic therapy in gynaecological neoplastic diseases. , 1996, Journal of photochemistry and photobiology. B, Biology.

[66]  R. Jindra,et al.  Experiences of photodynamic therapy in dermatology. , 1996, Journal of photochemistry and photobiology. B, Biology.

[67]  A. Welch,et al.  Optical properties of conjunctiva, sclera, and the ciliary body and their consequences for transscleral cyclophotocoagulation. , 1996, Applied optics.

[68]  Andre Roggan,et al.  Laser-Induced Interstitial Thermotherapy , 1995 .

[69]  I. S. Saidi,et al.  Mie and Rayleigh modeling of visible-light scattering in neonatal skin. , 1995, Applied optics.

[70]  L. Kou,et al.  Refractive indices of water and ice in the 0.65- to 2.5-µm spectral range. , 1993, Applied optics.

[71]  M. H. Koelink,et al.  Optical properties of human dermis in vitro and in vivo. , 1993, Applied optics.

[72]  J. Pickering,et al.  Double-integrating-sphere system for measuring the optical properties of tissue. , 1993, Applied optics.

[73]  A J Welch,et al.  Light dosimetry: effects of dehydration and thermal damage on the optical properties of the human aorta. , 1993, Applied optics.

[74]  A. Welch,et al.  Determining the optical properties of turbid mediaby using the adding-doubling method. , 1993, Applied optics.

[75]  K. Martin,et al.  Direct measurement of moisture in skin by NIR spectroscopy , 1993 .

[76]  B. Wilson,et al.  A diffusion theory model of spatially resolved, steady-state diffuse reflectance for the noninvasive determination of tissue optical properties in vivo. , 1992, Medical physics.

[77]  M. H. Koelink,et al.  Reduced light-scattering properties for mixtures of spherical particles: a simple approximation derived from Mie calculations. , 1992, Applied optics.

[78]  Gf Odland,et al.  The structure of the skin , 1991 .

[79]  L. Goldsmith.  Physiology, biochemistry, and molecular biology of the skin , 1991 .

[80]  M S Patterson,et al.  Optical properties of normal and diseased human breast tissues in the visible and near infrared. , 1990, Physics in medicine and biology.

[81]  F. A. Seiler,et al.  Numerical Recipes in C: The Art of Scientific Computing , 1989 .

[82]  A E Profio,et al.  Light transport in tissue. , 1989, Applied optics.

[83]  William H. Press,et al.  Numerical recipes in C. The art of scientific computing , 1987 .

[84]  Z. Kam,et al.  Absorption and Scattering of Light by Small Particles , 1998 .

[85]  W P James,et al.  Adipose tissue cellularity in man: the relationship between fat cell size and number, the mass and distribution of body fat and the history of weight gain and loss. , 1982, International journal of obesity.

[86]  K. Baker,et al.  Optical properties of the clearest natural waters (200-800 nm). , 1981, Applied optics.

[87]  Dudley A. Williams,et al.  Optical properties of water in the near infrared. , 1974 .