Effect of l-NAME, an inhibitor of nitric oxide synthesis, on plasma levels of IL-6, IL-8, TNFα and nitrite/nitrate in human septic shock

[1]  C. Hack,et al.  Time course of cytokine levels in sepsis , 1995, Intensive Care Medicine.

[2]  L. Lind,et al.  Proinflammatory cytokines, measured in a mixed population on arrival in the emergency department, are related to mortality and severity of disease , 1997, Journal of internal medicine.

[3]  J. Mege,et al.  Patterns of cytokine evolution (tumor necrosis factor-alpha and interleukin-6) after septic shock, hemorrhagic shock, and severe trauma. , 1997, Critical care medicine.

[4]  H. Bruining,et al.  Nitric oxide causes dysfunction of coronary autoregulation in endotoxemic rats. , 1997, Cardiovascular research.

[5]  J. Kienast,et al.  Nitric oxide synthase inhibition by L-NAME in leukocytopenic patients with severe septic shock , 1997, Intensive Care Medicine.

[6]  D. Remick,et al.  NITRIC OXIDE REGULATION OF INTERLEUKIN‐8 GENE EXPRESSION , 1997, Shock.

[7]  A. Eggermont,et al.  Effects of isolated limb perfusion with tumour necrosis factor‐alpha on the function of monocytes and T lymphocytes in patients with cancer , 1996, European journal of clinical investigation.

[8]  J. Bland,et al.  Plasma proinflammatory cytokine concentrations, Acute Physiology and Chronic Health Evaluation (APACHE) III scores and survival in patients in an intensive care unit. , 1996, Critical care medicine.

[9]  V. Cattell,et al.  Role of nitric oxide in immune-mediated diseases. , 1996, Clinical science.

[10]  S. Moncada,et al.  Direct measurement of nitric oxide in human beings , 1995, The Lancet.

[11]  T. Meyer,et al.  Nitric oxide inhibits LPS-induced IL-6 production in enterocytes. , 1995, The Journal of surgical research.

[12]  K. Fukatsu,et al.  Detrimental effects of a nitric oxide synthase inhibitor (N-omega-nitro-L-arginine-methyl-ester) in a murine sepsis model. , 1995, Archives of surgery.

[13]  S. Moncada,et al.  L-arginine: nitric oxide pathway in endotoxemia and human septic shock. , 1995, Critical care medicine.

[14]  A. Tedgui,et al.  Effects of inhibition of nitric oxide synthesis on TNF alpha serum levels in E. coli endotoxemic rats. , 1995, Life sciences.

[15]  M. Goldman,et al.  The protective role of endogenously synthesized nitric oxide in staphylococcal enterotoxin B-induced shock in mice , 1994, The Journal of experimental medicine.

[16]  G. Tiao,et al.  Detrimental effect of nitric oxide synthase inhibition during endotoxemia may be caused by high levels of tumor necrosis factor and interleukin-6. , 1994, Surgery.

[17]  J. Lorente,et al.  Inhibition of nitric oxide synthesis improves the vasoconstrictive effect of noradrenaline in sepsis. , 1994, Chest.

[18]  S Moncada,et al.  Nitric oxide is present in exhaled breath in humans: direct GC-MS confirmation. , 1994, Biochemical and biophysical research communications.

[19]  S. Moncada,et al.  Effects of a nitric oxide synthase inhibitor in humans with septic shock. , 1994, Cardiovascular research.

[20]  J. Lorente,et al.  L‐arginine pathway in the sepsis syndrome , 1993, Critical care medicine.

[21]  J. Parrillo Pathogenetic mechanisms of septic shock. , 1993, The New England journal of medicine.

[22]  M. Baggiolini,et al.  Interleukin‐8, a chemotactic and inflammatory cytokine , 1992, FEBS letters.

[23]  D. Herndon,et al.  Reversal of hyperdynamic response to continuous endotoxin administration by inhibition of NO synthesis. , 1992, Journal of applied physiology.

[24]  A. Peitzman,et al.  Nitrogen oxide levels in patients after trauma and during sepsis. , 1991, Annals of surgery.

[25]  S. Moncada,et al.  Nitric oxide: physiology, pathophysiology, and pharmacology. , 1991, Pharmacological reviews.

[26]  H. Cheng,et al.  Nitric oxide synthesis in the CNS endothelium and macrophages differs in its sensitivity to inhibition by arginine analogues. , 1991, Life sciences.

[27]  S. Tannenbaum,et al.  Nitrate biosynthesis in rats, ferrets and humans. Precursor studies with L-arginine. , 1990, Carcinogenesis.

[28]  J. Adams,et al.  hypotension: Implications for the involvement of nitric oxide , 2022 .

[29]  J. Snick,et al.  Interleukin-6: an overview. , 1990, Annual review of immunology.

[30]  J. Van Snick Interleukin-6: an overview. , 1990, Annual review of immunology.

[31]  F. Ognibene,et al.  clinical investigations in critical care Right Ventricular Dysfunction and Dilatation , Similar to Left Ventricular Changes , Characterize the Cardiac Depression of Septic Shock in Humans * , 2006 .

[32]  E. A. Havell Evidence that tumor necrosis factor has an important role in antibacterial resistance. , 1989, Journal of immunology.

[33]  T. Clemmer,et al.  Sepsis syndrome: a valid clinical entity , 1989 .

[34]  D. Gemsa,et al.  Release of tumor necrosis factor-alpha from macrophages. Enhancement and suppression are dose-dependently regulated by prostaglandin E2 and cyclic nucleotides. , 1988, Journal of immunology.

[35]  B. Beutler,et al.  Cachectin: more than a tumor necrosis factor. , 1987, The New England journal of medicine.

[36]  J. L. Gall,et al.  APACHE II--a severity of disease classification system. , 1986, Critical care medicine.

[37]  S. Al-Dabbagh,et al.  The estimation of nitrate and nitrite in saliva and urine. , 1983, Analytical biochemistry.