Wild Lonicera caerulea berry polyphenol extract reduces cholesterol accumulation and enhances antioxidant capacity in vitro and in vivo.

[1]  D. Hou,et al.  Polyphenols from Lonicera caerulea L. berry attenuate experimental nonalcoholic steatohepatitis by inhibiting proinflammatory cytokines productions and lipid peroxidation , 2017, Molecular nutrition & food research.

[2]  Chih-Yang Huang,et al.  Dietary potato peel extract reduces the toxicity of cholesterol oxidation products in rats , 2016 .

[3]  Xianjun Meng,et al.  Effects of high hydrostatic pressure on physicochemical properties, enzymes activity, and antioxidant capacities of anthocyanins extracts of wild Lonicera caerulea berry , 2016 .

[4]  M. Mi,et al.  Resveratrol Attenuates Trimethylamine-N-Oxide (TMAO)-Induced Atherosclerosis by Regulating TMAO Synthesis and Bile Acid Metabolism via Remodeling of the Gut Microbiota , 2016, mBio.

[5]  A. Wojdyło,et al.  Effect of dried powder preparation process on polyphenolic content and antioxidant activity of blue honeysuckle berries (Lonicera caerulea L. var. kamtschatica) , 2016 .

[6]  S. Hazen,et al.  Gut Microbial Metabolite TMAO Enhances Platelet Hyperreactivity and Thrombosis Risk , 2016, Cell.

[7]  A. Guadarrama,et al.  Bioavailability and the mechanism of action of a grape extract rich in polyphenols in cholesterol homeostasis , 2016 .

[8]  Yuan-ting Xiao,et al.  Chlorogenic acid-enriched extract from Eucommia ulmoides leaves inhibits hepatic lipid accumulation through regulation of cholesterol metabolism in HepG2 cells , 2016, Pharmaceutical biology.

[9]  Dan Feng,et al.  Lycopene reduces cholesterol absorption through the downregulation of Niemann-Pick C1-like 1 in Caco-2 cells. , 2015, Molecular nutrition & food research.

[10]  R. Martín-Hernández,et al.  Modulation of Cholesterol-Related Gene Expression by Dietary Fiber Fractions from Edible Mushrooms. , 2015, Journal of agricultural and food chemistry.

[11]  Soyoung Lee,et al.  Barley sprout extract containing policosanols and polyphenols regulate AMPK, SREBP2 and ACAT2 activity and cholesterol and glucose metabolism in vitro and in vivo , 2015 .

[12]  R. Jiao,et al.  Cholesterol-lowering activity of sesamin is associated with down-regulation on genes of sterol transporters involved in cholesterol absorption. , 2015, Journal of agricultural and food chemistry.

[13]  D. Prim,et al.  Identification of bioaccessible and uptaken phenolic compounds from strawberry fruits in in vitro digestion/Caco-2 absorption model. , 2015, Food chemistry.

[14]  A. D’Amato,et al.  Lupin peptides lower low-density lipoprotein (LDL) cholesterol through an up-regulation of the LDL receptor/sterol regulatory element binding protein 2 (SREBP2) pathway at HepG2 cell line. , 2014, Journal of agricultural and food chemistry.

[15]  Chun-mei Li,et al.  Persimmon tannin accounts for hypolipidemic effects of persimmon through activating of AMPK and suppressing NF-κB activation and inflammatory responses in high-fat diet rats. , 2014, Food & function.

[16]  S. Hazen,et al.  Measurement of trimethylamine-N-oxide by stable isotope dilution liquid chromatography tandem mass spectrometry. , 2014, Analytical biochemistry.

[17]  R. Jiao,et al.  Cholesteryl ester species differently elevate plasma cholesterol in hamsters. , 2013, Journal of agricultural and food chemistry.

[18]  Su-hong Li,et al.  Pectin pentasaccharide from hawthorn (Crataegus pinnatifida Bunge. Var. major) ameliorates disorders of cholesterol metabolism in high-fat diet fed mice , 2013 .

[19]  Bohkyung Kim,et al.  Polyphenol-rich black chokeberry (Aronia melanocarpa) extract regulates the expression of genes critical for intestinal cholesterol flux in Caco-2 cells. , 2013, The Journal of nutritional biochemistry.

[20]  A. Jurgoński,et al.  An anthocyanin-rich extract from Kamchatka honeysuckle increases enzymatic activity within the gut and ameliorates abnormal lipid and glucose metabolism in rats. , 2013, Nutrition.

[21]  Chun-Wai Wan,et al.  Chlorogenic Acid Exhibits Cholesterol Lowering and Fatty Liver Attenuating Properties by Up‐regulating the Gene Expression of PPAR‐α in Hypercholesterolemic Rats Induced with a High‐Cholesterol Diet , 2013, Phytotherapy research : PTR.

[22]  Yu’e Jiang,et al.  Blueberry anthocyanins at doses of 0.5 and 1 % lowered plasma cholesterol by increasing fecal excretion of acidic and neutral sterols in hamsters fed a cholesterol-enriched diet , 2013, European Journal of Nutrition.

[23]  Yong-hui Shi,et al.  Alterations of the gut microbiota in high-fat diet mice is strongly linked to oxidative stress , 2013, Applied Microbiology and Biotechnology.

[24]  T. Jin,et al.  Cyanidin-3-O-β-glucoside upregulates hepatic cholesterol 7α-hydroxylase expression and reduces hypercholesterolemia in mice. , 2012, Molecular nutrition & food research.

[25]  T. Ha,et al.  Long-term curcumin administration protects against atherosclerosis via hepatic regulation of lipoprotein cholesterol metabolism. , 2011, Molecular nutrition & food research.

[26]  C. Peng,et al.  Role and classification of cholesterol-lowering functional foods , 2011 .

[27]  P. Dussault,et al.  Phytosterol Ester Constituents Affect Micellar Cholesterol Solubility in Model Bile , 2010, Lipids.

[28]  L. Ohlsson,et al.  Curcumin inhibits cholesterol uptake in Caco-2 cells by down-regulation of NPC1L1 expression , 2010, Lipids in Health and Disease.

[29]  J. Cristol,et al.  Polysaccharides from the green alga Ulva rigida improve the antioxidant status and prevent fatty streak lesions in the high cholesterol fed hamster, an animal model of nutritionally-induced atherosclerosis , 2009 .

[30]  S. Luquet,et al.  Short-term adaptation of postprandial lipoprotein secretion and intestinal gene expression to a high-fat diet. , 2009, American journal of physiology. Gastrointestinal and liver physiology.

[31]  Yu Huang,et al.  Apple polyphenols inhibit plasma CETP activity and reduce the ratio of non-HDL to HDL cholesterol. , 2008, Molecular nutrition & food research.

[32]  Chae-Wook Kim,et al.  GCG-Rich Tea Catechins are Effective in Lowering Cholesterol and Triglyceride Concentrations in Hyperlipidemic Rats , 2008, Lipids.

[33]  K. Lora,et al.  High saturated fat and cholesterol intakes and abnormal plasma lipid concentrations observed in a group of 4- to 8-year-old children of Latino immigrants in rural Nebraska , 2007 .

[34]  T. Kanda,et al.  Absorption of Dietary Cholesterol Oxidation Products and Their Downstream Metabolic Effects Are Reduced by Dietary Apple Polyphenols , 2007, Lipids.

[35]  Robert V Farese,et al.  Plasma Cholesteryl Esters Provided by Lecithin:Cholesterol Acyltransferase and Acyl-Coenzyme A:Cholesterol Acyltransferase 2 Have Opposite Atherosclerotic Potential , 2004, Circulation research.

[36]  Robert V Farese,et al.  ACAT2 deficiency limits cholesterol absorption in the cholesterol‐fed mouse: Impact on hepatic cholesterol homeostasis , 2004, Hepatology.

[37]  Jonathan C. Cohen,et al.  Stimulation of Cholesterol Excretion by the Liver X Receptor Agonist Requires ATP-binding Cassette Transporters G5 and G8* , 2003, The Journal of Biological Chemistry.

[38]  M. Ananthanarayanan,et al.  Hypercholesterolemia and changes in lipid and bile acid metabolism in male and female cyp7A1-deficient mice Published, JLR Papers in Press, February 16, 2003. DOI 10.1194/jlr.M200489-JLR200 , 2003, Journal of Lipid Research.

[39]  Colin D Kay,et al.  Absorption of anthocyanins from blueberries and serum antioxidant status in human subjects. , 2002, Journal of agricultural and food chemistry.

[40]  N. Borradaile,et al.  Inhibition of hepatocyte apoB secretion by naringenin: enhanced rapid intracellular degradation independent of reduced microsomal cholesteryl esters. , 2002, Journal of lipid research.

[41]  Thomas D. Schmittgen,et al.  Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. , 2001, Methods.

[42]  C. E. Taylor,et al.  Potential infectious etiologies of atherosclerosis: a multifactorial perspective. , 2001, Emerging infectious diseases.

[43]  M. Nair,et al.  Antioxidant and antiinflammatory activities of anthocyanins and their aglycon, cyanidin, from tart cherries. , 1999, Journal of natural products.

[44]  M. M. Bradford A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. , 1976, Analytical biochemistry.

[45]  R. Jiao,et al.  Hypocholesterolemic activity of buckwheat flour is mediated by increasing sterol excretion and down-regulation of intestinal NPC1L1 and ACAT2 , 2014 .

[46]  Luquan Wang,et al.  Materials and Methods Figs. S1 to S4 Tables S1 and S2 References Niemann-pick C1 like 1 Protein Is Critical for Intestinal Cholesterol Absorption , 2022 .