Cyclin E in normal and neoplastic cell cycles

[1]  Allan Balmain,et al.  Fbxw7/Cdc4 is a p53-dependent, haploinsufficient tumour suppressor gene , 2004, Nature.

[2]  S. Elledge,et al.  Recognition of Phosphodegron Motifs in Human Cyclin E by the SCFFbw7 Ubiquitin Ligase* , 2004, Journal of Biological Chemistry.

[3]  J. Maller,et al.  A Centrosomal Localization Signal in Cyclin E Required for Cdk2-Independent S Phase Entry , 2004, Science.

[4]  Bruce Stillman,et al.  Deregulation of cyclin E in human cells interferes with prereplication complex assembly , 2004, The Journal of cell biology.

[5]  R. Coates,et al.  Racial differences in the expression of cell cycle–regulatory proteins in breast carcinoma , 2004, Cancer.

[6]  B. Clurman,et al.  The Fbw7 tumor suppressor regulates glycogen synthase kinase 3 phosphorylation-dependent c-Myc protein degradation , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[7]  S. Elledge,et al.  Defective cardiovascular development and elevated cyclin E and Notch proteins in mice lacking the Fbw7 F-box protein. , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[8]  Y. Bessho,et al.  Mouse Fbw7/Sel-10/Cdc4 Is Required for Notch Degradation during Vascular Development* , 2004, Journal of Biological Chemistry.

[9]  Carlo Rago,et al.  Inactivation of hCDC4 can cause chromosomal instability , 2004, Nature.

[10]  A. Behrens,et al.  The Ubiquitin Ligase SCFFbw7 Antagonizes Apoptotic JNK Signaling , 2004, Science.

[11]  A. Zetterberg,et al.  Mutation of hCDC4 Leads to Cell Cycle Deregulation of Cyclin E in Cancer , 2004, Cancer Research.

[12]  S. Semba,et al.  Expression of cyclin E in colorectal adenomas and adenocarcinomas: correlation with expression of Ki-67 antigen and p53 protein , 1996, Virchows Archiv.

[13]  J. Cigudosa,et al.  Cyclin E gene (CCNE) amplification and hCDC4 mutations in endometrial carcinoma , 2003, The Journal of pathology.

[14]  S. Elledge,et al.  BTB proteins are substrate-specific adaptors in an SCF-like modular ubiquitin ligase containing CUL-3 , 2003, Nature.

[15]  M. Tyers,et al.  The BTB protein MEL-26 is a substrate-specific adaptor of the CUL-3 ubiquitin-ligase , 2003, Nature.

[16]  Yan Geng,et al.  Cyclin E Ablation in the Mouse , 2003, Cell.

[17]  Sehwan Han,et al.  Prognostic implication of cyclin E expression and its relationship with cyclin D1 and p27Kip1 expression on tissue microarrays of node negative breast cancer , 2003, Journal of surgical oncology.

[18]  C. Sweep,et al.  Cyclin-E is a strong predictor of endocrine therapy failure in human breast cancer , 2003, Oncogene.

[19]  J. Kononen,et al.  Cyclin E overexpression and amplification in human tumours , 2003, The Journal of pathology.

[20]  R. Altura,et al.  Inactivation of E2F3 results in centrosome amplification. , 2003, Cancer cell.

[21]  T. Möröy,et al.  Loss of p27Kip1 cooperates with cyclin E in T-cell lymphomagenesis , 2003, Oncogene.

[22]  Frank McCormick,et al.  Proliferation of cancer cells despite CDK2 inhibition. , 2003, Cancer cell.

[23]  M. Tyers,et al.  Structural Basis for Phosphodependent Substrate Selection and Orientation by the SCFCdc4 Ubiquitin Ligase , 2003, Cell.

[24]  Isabelle Bedrosian,et al.  Cyclin E and survival in patients with breast cancer. , 2002, The New England journal of medicine.

[25]  T. Möröy,et al.  The Oncogenic Activity of Cyclin E Is Not Confined to Cdk2 Activation Alone but Relies on Several Other, Distinct Functions of the Protein* , 2002, The Journal of Biological Chemistry.

[26]  F. McCormick,et al.  The RB and p53 pathways in cancer. , 2002, Cancer cell.

[27]  S. Reed,et al.  Human F-box protein hCdc4 targets cyclin E for proteolysis and is mutated in a breast cancer cell line , 2001, Nature.

[28]  Daniel A. Haber,et al.  Archipelago regulates Cyclin E levels in Drosophila and is mutated in human cancer cell lines , 2001, Nature.

[29]  A. Ciechanover,et al.  Functional Interaction between SEL-10, an F-box Protein, and the Nuclear Form of Activated Notch1 Receptor* , 2001, The Journal of Biological Chemistry.

[30]  S. Elledge,et al.  Phosphorylation-Dependent Ubiquitination of Cyclin E by the SCFFbw7 Ubiquitin Ligase , 2001, Science.

[31]  Y. Geng,et al.  Specific protection against breast cancers by cyclin D1 ablation , 2001, Nature.

[32]  H. F. Horn,et al.  Specific Phosphorylation of Nucleophosmin on Thr199 by Cyclin- dependent Kinase 2-Cyclin E and Its Role in Centrosome Duplication* , 2001, The Journal of Biological Chemistry.

[33]  P. Jackson,et al.  Cyclin E Uses Cdc6 as a Chromatin-Associated Receptor Required for DNA Replication , 2001, The Journal of cell biology.

[34]  J. Harper,et al.  A premature-termination mutation in the Mus musculus cyclin-dependent kinase 3 gene. , 2001, Proceedings of the National Academy of Sciences of the United States of America.

[35]  G. Landberg,et al.  Prognostic Implications of p27 and Cyclin E Protein Contents in Malignant Lymphomas , 2001, Leukemia & lymphoma.

[36]  K. Keyomarsi,et al.  Novel splice variants of cyclin E with altered substrate specificity. , 2000, Nucleic acids research.

[37]  H. F. Horn,et al.  Nucleophosmin/B23 Is a Target of CDK2/Cyclin E in Centrosome Duplication , 2000, Cell.

[38]  A. Ballester,et al.  Ectopic expression of cyclin E allows non-endomitotic megakaryoblastic K562 cells to establish re-replication cycles , 2000, Oncogene.

[39]  T. Möröy,et al.  Oncogenic potential of cyclin E in T-cell lymphomagenesis in transgenic mice: evidence for cooperation between cyclin E and Ras but not Myc , 1999, Oncogene.

[40]  S. Reed,et al.  Deregulated cyclin E induces chromosome instability , 1999, Nature.

[41]  Rene H Medema,et al.  Rescue of Cyclin D1 Deficiency by Knockin Cyclin E , 1999, Cell.

[42]  T. Stearns,et al.  Cyclin-dependent kinase control of centrosome duplication. , 1999, Proceedings of the National Academy of Sciences of the United States of America.

[43]  J. Maller,et al.  Requirement of Cdk2-cyclin E activity for repeated centrosome reproduction in Xenopus egg extracts. , 1999, Science.

[44]  Jidong Liu,et al.  Cyclin E2, a novel human G1 cyclin and activating partner of CDK2 and CDK3, is induced by viral oncoproteins , 1998, Oncogene.

[45]  W. Reith,et al.  Cyclin E2: a novel CDK2 partner in the late G1 and S phases of the mammalian cell cycle , 1998, Oncogene.

[46]  J. Girault,et al.  Histone acetyltransferase activity of CBP is controlled by cycle-dependent kinases and oncoprotein E1A , 1998, Nature.

[47]  B. Schulman,et al.  Substrate recruitment to cyclin-dependent kinase 2 by a multipurpose docking site on cyclin A. , 1998, Proceedings of the National Academy of Sciences of the United States of America.

[48]  J. Roberts,et al.  Identification of a substrate-targeting domain in cyclin E necessary for phosphorylation of the retinoblastoma protein. , 1998, Proceedings of the National Academy of Sciences of the United States of America.

[49]  J. Bartek,et al.  The retinoblastoma protein pathway in cell cycle control and cancer. , 1997, Experimental cell research.

[50]  T. Möröy,et al.  Malignant transformation by cyclin E and Ha-Ras correlates with lower sensitivity towards induction of cell death but requires functional Myc and CDK4 , 1997, Oncogene.

[51]  M. Tanimoto,et al.  Overexpression of cyclin E in acute myelogenous leukemia. , 1997, Blood.

[52]  Mike Tyers,et al.  F-Box Proteins Are Receptors that Recruit Phosphorylated Substrates to the SCF Ubiquitin-Ligase Complex , 1997, Cell.

[53]  G. Landberg,et al.  Cyclin E overexpression, a negative prognostic factor in breast cancer with strong correlation to oestrogen receptor status. , 1996, British Journal of Cancer.

[54]  J. Nevins,et al.  Regulation of the cyclin E gene by transcription factor E2F1. , 1995, Proceedings of the National Academy of Sciences of the United States of America.

[55]  Anindya Dutta,et al.  Cyclins as markers of tumor proliferation: immunocytochemical studies in breast cancer. , 1995, Proceedings of the National Academy of Sciences of the United States of America.

[56]  C. Sherr G1 phase progression: Cycling on cue , 1994, Cell.

[57]  C. Lehner,et al.  Cyclin E controls S phase progression and its down-regulation during Drosophila embryogenesis is required for the arrest of cell proliferation , 1994, Cell.

[58]  S. van den Heuvel,et al.  Distinct roles for cyclin-dependent kinases in cell cycle control. , 1993, Science.

[59]  R. Weinberg,et al.  Physical interaction of the retinoblastoma protein with human D cyclins , 1993, Cell.

[60]  James M. Roberts,et al.  Cyclin-dependent regulation of G1 in mammalian fibroblasts. , 1993, Science.

[61]  K. Keyomarsi,et al.  Redundant cyclin overexpression and gene amplification in breast cancer cells. , 1993, Proceedings of the National Academy of Sciences of the United States of America.

[62]  S. Reed,et al.  Association of human cyclin E with a periodic G1-S phase protein kinase. , 1992, Science.

[63]  James M. Roberts,et al.  Formation and activation of a cyclin E-cdk2 complex during the G1 phase of the human cell cycle , 1992 .

[64]  James M. Roberts,et al.  Human cyclin E, a new cyclin that interacts with two members of the CDC2 gene family , 1991, Cell.

[65]  S. Reed,et al.  Isolation of three novel human cyclins by rescue of G1 cyclin (cln) function in yeast , 1991, Cell.