Tiotropium improves lung function in patients with severe uncontrolled asthma: a randomized controlled trial.

[1]  E. Bateman,et al.  Tiotropium is noninferior to salmeterol in maintaining improved lung function in B16-Arg/Arg patients with asthma. , 2011, The Journal of allergy and clinical immunology.

[2]  E. R. Sutherland,et al.  Tiotropium bromide step-up therapy for adults with uncontrolled asthma. , 2010, The New England journal of medicine.

[3]  E. Bateman,et al.  A one-year trial of tiotropium Respimat plus usual therapy in COPD patients. , 2010, Respiratory medicine.

[4]  L. Puttagunta,et al.  The efficacy of tiotropium as a steroid-sparing agent in severe asthma. , 2009, Canadian respiratory journal.

[5]  K. Min,et al.  Additive role of tiotropium in severe asthmatics and Arg16Gly in ADRB2 as a potential marker to predict response , 2009, Allergy.

[6]  J. V. van Noord,et al.  The efficacy of tiotropium administered via Respimat Soft Mist Inhaler or HandiHaler in COPD patients. , 2009, Respiratory medicine.

[7]  M. Decramer,et al.  A 4-year trial of tiotropium in chronic obstructive pulmonary disease. , 2008, The New England journal of medicine.

[8]  N. Kohno,et al.  Tiotropium bromide is effective for severe asthma with noneosinophilic phenotype , 2008, European Respiratory Journal.

[9]  H. Magnussen,et al.  Improvements with tiotropium in COPD patients with concomitant asthma. , 2008, Respiratory medicine.

[10]  A. Halayko,et al.  Inhibition of allergen-induced airway remodelling by tiotropium and budesonide: a comparison , 2007, European Respiratory Journal.

[11]  W. Busse,et al.  Severe asthma in adults: what are the important questions? , 2007, The Journal of allergy and clinical immunology.

[12]  S. Peters,et al.  Real-world Evaluation of Asthma Control and Treatment (REACT): findings from a national Web-based survey. , 2007, The Journal of allergy and clinical immunology.

[13]  B. Lipworth,et al.  A proof of concept study to evaluate stepping down the dose of fluticasone in combination with salmeterol and tiotropium in severe persistent asthma. , 2007, Respiratory medicine.

[14]  N. Gross Anticholinergic agents in asthma and COPD. , 2006, European journal of pharmacology.

[15]  J. V. van Noord,et al.  Comparison of tiotropium once daily, formoterol twice daily and both combined once daily in patients with COPD , 2005, European Respiratory Journal.

[16]  R. Gosens,et al.  Protective effects of tiotropium bromide in the progression of airway smooth muscle remodeling. , 2005, American journal of respiratory and critical care medicine.

[17]  R. Pauwels,et al.  Can guideline-defined asthma control be achieved? The Gaining Optimal Asthma ControL study. , 2004, American journal of respiratory and critical care medicine.

[18]  Anticholinergic agents for chronic asthma in adults. , 2004, The Cochrane database of systematic reviews.

[19]  R. Zuwallack,et al.  A long-term evaluation of once-daily inhaled tiotropium in chronic obstructive pulmonary disease , 2002, European Respiratory Journal.

[20]  M. Littner,et al.  Long-acting bronchodilation with once-daily dosing of tiotropium (Spiriva) in stable chronic obstructive pulmonary disease. , 2000, American journal of respiratory and critical care medicine.

[21]  C. Rodrigo,et al.  A meta-analysis of the effects of ipratropium bromide in adults with acute asthma. , 1999, The American journal of medicine.

[22]  G. Guyatt,et al.  Development and validation of the Mini Asthma Quality of Life Questionnaire. , 1999, The European respiratory journal.

[23]  T. Witek,et al.  Tiotropium (Spiriva): mechanistical considerations and clinical profile in obstructive lung disease. , 1999, Life sciences.

[24]  R. Pauwels,et al.  GLOBAL STRATEGY FOR ASTHMA MANAGEMENT AND PREVENTION , 1996 .

[25]  J E Cotes,et al.  Lung volumes and forced ventilatory flows , 1993, European Respiratory Journal.

[26]  J E Cotes,et al.  Lung volumes and forced ventilatory flows. Report Working Party Standardization of Lung Function Tests, European Community for Steel and Coal. Official Statement of the European Respiratory Society. , 1993, The European respiratory journal. Supplement.