Cost savings associated with video directly observed therapy for treatment of tuberculosis.

OBJECTIVE: To calculate the per-session and annual direct program costs to implement directly observed therapy (DOT) for tuberculosis treatment and to conduct a cost attribution analysis under varying proportions of DOT utilization for four DOT types.DESIGN: Program data covering the study period from September 2014 to August 2015 in New York City (NYC) were used to conduct a retrospective bottom-up micro-costing economic evaluation. For each DOT type, potential per-session and annual program savings were estimated as the cost averted by adopting a uniform distribution of DOT alternatives. Sensitivity analyses explored aggregate cost impacts of unequal distributions.RESULTS: There was a total of 38 035 unique DOT visits, of which 12 002 (32%) were clinic-based (CDOT); 15 483 (41%) were field-based (FDOT); 7185 (19%) were live-video (LVDOT); and 3365 (9%) were recorded-video (RVDOT). The per-session direct costs (in 2016 $US) for DOT services delivered during the study period were $8.46 for CDOT; $19.83 for FDOT; $6.54 for LVDOT; and $5.35 for RVDOT. Sensitivity analyses supported the main findings.CONCLUSIONS: Significant cost savings were estimated with increased utilization of VDOT. Assuming equivalent treatment adherence, duration, completion, and adverse events across DOT types, RVDOT was the modality that most minimized cost.

[1]  John L. Johnson,et al.  A patient-level pooled analysis of treatment-shortening regimens for drug-susceptible pulmonary tuberculosis , 2018, Nature Medicine.

[2]  F. Raab,et al.  Tuberculosis Treatment Monitoring by Video Directly Observed Therapy in 5 Health Districts, California, USA , 2018, Emerging infectious diseases.

[3]  M. Lobato,et al.  A National Survey on the Use of Electronic Directly Observed Therapy for Treatment of Tuberculosis , 2017, Journal of public health management and practice : JPHMP.

[4]  T. Buchman,et al.  A New Method to Directly Observe Tuberculosis Treatment: Skype Observed Therapy, a Patient-Centered Approach , 2017, Journal of public health management and practice : JPHMP.

[5]  R. Garfein,et al.  A Qualitative Study Exploring Stakeholder Perceptions of Video Directly Observed Therapy for Monitoring Tuberculosis Treatment in the US-Mexico Border Region , 2016 .

[6]  J. Burzynski,et al.  Enhancing management of tuberculosis treatment with video directly observed therapy in New York City. , 2016, The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease.

[7]  D. John,et al.  Cost‐optimization in the treatment of multidrug resistant tuberculosis in Nigeria , 2016, Tropical medicine & international health : TM & IH.

[8]  K. Patrick,et al.  Feasibility of tuberculosis treatment monitoring by video directly observed therapy: a binational pilot study. , 2015, The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease.

[9]  M. Mirsaeidi,et al.  Video directly observed therapy for treatment of tuberculosis is patient-oriented and cost-effective , 2015, European Respiratory Journal.

[10]  M. Hendriks,et al.  Step-by-step guideline for disease-specific costing studies in low- and middle-income countries: a mixed methodology , 2014, Global health action.

[11]  P Cooley,et al.  Videophone utilization as an alternative to directly observed therapy for tuberculosis. , 2010, The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease.

[12]  Kevin D Frick,et al.  Microcosting Quantity Data Collection Methods , 2009, Medical care.

[13]  A. Tice,et al.  The application of telemedicine technology to a directly observed therapy program for tuberculosis: a pilot project. , 2001, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

[14]  B. O'brien,et al.  The death of cost-minimization analysis? , 2001, Health economics.

[15]  S. Wilson Methods for the economic evaluation of health care programmes , 1987 .

[16]  Vital Hepatitis Std Aids,et al.  Reported tuberculosis in the United States 2013 , 2014 .