Tissue transglutaminase selectively modifies gliadin peptides that are recognized by gut-derived T cells in celiac disease

[1]  E. Thorsby,et al.  CD4+ T cells with specific reactivity against astrovirus isolated from normal human small intestine. , 1998, Gastroenterology.

[2]  K. Lundin,et al.  Autoantibodies in coeliac disease: tissue transglutaminase—guilt by association? , 1997, Gut.

[3]  D. Schuppan,et al.  Identification of tissue transglutaminase as the autoantigen of celiac disease , 1997, Nature Medicine.

[4]  A. Agulnik,et al.  The HLA-A*0201-restricted H-Y antigen contains a posttranslationally modified cysteine that significantly affects T cell recognition. , 1997, Immunity.

[5]  C. Watts,et al.  Capture and processing of exogenous antigens for presentation on MHC molecules. , 1997, Annual review of immunology.

[6]  H. Green,et al.  Peptides containing glutamine repeats as substrates for transglutaminase-catalyzed cross-linking: relevance to diseases of the nervous system. , 1996, Proceedings of the National Academy of Sciences of the United States of America.

[7]  G. Nepom,et al.  HLA-DQB1 codon 57 is critical for peptide binding and recognition , 1996, The Journal of experimental medicine.

[8]  E. Thorsby,et al.  Identification of a putative motif for binding of peptides to HLA-DQ2. , 1996, International immunology.

[9]  J. Shabanowitz,et al.  An HLA-A2-restricted tyrosinase antigen on melanoma cells results from posttranslational modification and suggests a novel pathway for processing of membrane proteins , 1996, The Journal of experimental medicine.

[10]  V. Kouskoff,et al.  Cassette vectors directing expression of T cell receptor genes in transgenic mice. , 1995, Journal of immunological methods.

[11]  E. Thorsby,et al.  T cells from the small intestinal mucosa of a DR4, DQ7/DR4, DQ8 celiac disease patient preferentially recognize gliadin when presented by DQ8. , 1994, Human immunology.

[12]  R. Holmdahl,et al.  T cell recognition of carbohydrates on type II collagen , 1994, The Journal of experimental medicine.

[13]  E. Thorsby,et al.  T Cells from the Peripheral Blood of Coeliac Disease Patients Recognize Gluten Antigens when Presented by HLA‐DR, ‐DQ, or ‐DP Molecules , 1994, Scandinavian journal of immunology.

[14]  M. Paulsson,et al.  Transglutaminases: Protein Cross-Linking Enzymes in Tissues and Body Fluids , 1994, Thrombosis and Haemostasis.

[15]  Hamada Js Deamidation of food proteins to improve functionality , 1994 .

[16]  E. Thorsby,et al.  HLA susceptibility genes in celiac disease: genetic mapping and role in pathogenesis. , 1993, Gastroenterology.

[17]  C. Larré,et al.  GLIADIN MODIFICATIONS CATALYZED BY GUINEA PIG LIVER TRANSGLUTAMINASE , 1993 .

[18]  E. Thorsby,et al.  Gliadin-specific, HLA-DQ(alpha 1*0501,beta 1*0201) restricted T cells isolated from the small intestinal mucosa of celiac disease patients , 1993, The Journal of experimental medicine.

[19]  T. Halstensen,et al.  5.4 In situ two- and three-color immunofluorescence staining of mucosal T-cells in celiac disease: Increase of TCRγ/δ+CD8- and TCRα/β+CD45R0+ intraepithelial lymphocytes and IL-2R+ TCRα/β+CD4+CD45R0+ lamina propria lymphocytes , 1992 .

[20]  B. Malissen,et al.  Derivation of a T cell hybridoma variant deprived of functional T cell receptor α and β chain transcripts reveals a nonfunctional α‐mRNA of BW5147 origin , 1989, European journal of immunology.

[21]  M. Mann,et al.  Electrospray ionization for mass spectrometry of large biomolecules. , 1989, Science.

[22]  M. Karas,et al.  Laser desorption ionization of proteins with molecular masses exceeding 10,000 daltons. , 1988, Analytical chemistry.

[23]  J R Yates,et al.  Protein sequencing by tandem mass spectrometry. , 1986, Proceedings of the National Academy of Sciences of the United States of America.

[24]  R. Kannagi,et al.  Possible Involvement of Transglutaminase in Endocytosis and Antigen Presentation , 1985, Microbiology and immunology.

[25]  T. Peters,et al.  Human jejunal transglutaminase: demonstration of activity, enzyme kinetics and substrate specificity with special relation to gliadin and coeliac disease. , 1985, Clinical science.

[26]  J. E. Folk Mechanism and basis for specificity of transglutaminase-catalyzed epsilon-(gamma-glutamyl) lysine bond formation. , 1983, Advances in enzymology and related areas of molecular biology.

[27]  I. Pastan,et al.  Transglutaminase is essential in receptor-mediated endocytosis of α2-macroglobulin and polypeptide hormones , 1980, Nature.

[28]  A. Frazer,et al.  Gluten-induced enteropathy: the effect of partially digested gluten. , 1959, Lancet.