Notch and the immune system.

[1]  M. Bevan,et al.  Correlating notch signaling with thymocyte maturation. , 1998, Immunity.

[2]  I. Bernstein,et al.  The Notch ligand, Jagged-1, influences the development of primitive hematopoietic precursor cells. , 1998, Blood.

[3]  F. Kuo,et al.  Isolation and functional analysis of a cDNA for human Jagged2, a gene encoding a ligand for the Notch1 receptor , 1997, Molecular and cellular biology.

[4]  Iva Greenwald,et al.  Presenilin is required for activity and nuclear access of Notch in Drosophila , 1999, Nature.

[5]  I. Bernstein,et al.  Inhibition of granulocytic differentiation by mNotch1. , 1996, Proceedings of the National Academy of Sciences of the United States of America.

[6]  I. Bernstein,et al.  A human homologue of the Drosophila developmental gene, Notch, is expressed in CD34+ hematopoietic precursors. , 1994, Blood.

[7]  A. Winoto.  Genes involved in T-cell receptor-mediated apoptosis of thymocytes and T-cell hybridomas. , 1997, Seminars in Immunology.

[8]  U. Lendahl,et al.  Notch-related genes in animal development. , 1995, The International journal of developmental biology.

[9]  U. Lendahl,et al.  The notch 3 intracellular domain represses notch 1-mediated activation through Hairy/Enhancer of split (HES) promoters. , 1999, Development.

[10]  C. van Broeckhoven,et al.  Presenilin mutations in Alzheimer's disease , 1998, Human mutation.

[11]  J. Sklar,et al.  Modulated expression of notch1 during thymocyte development , 1996 .

[12]  J. R. Coleman,et al.  Mutation in ankyrin repeats of the mouse Notch2 gene induces early embryonic lethality. , 1999, Development.

[13]  I. Greenwald,et al.  LIN-12/Notch signaling: lessons from worms and flies. , 1998, Genes & development.

[14]  B. Fowlkes,et al.  Notch Activity Influences the αβ versus γδ T Cell Lineage Decision , 1997, Cell.

[15]  G. Weinmaster,et al.  The Ins and Outs of Notch Signaling , 1997, Molecular and Cellular Neuroscience.

[16]  L. Schwartz,et al.  Apoptotic signals delivered through the T-cell receptor of a T-cell hybrid require the immediate–early gene nur77 , 1994, Nature.

[17]  J. Rossant,et al.  Notch1 is required for the coordinate segmentation of somites. , 1995, Development.

[18]  S. Artavanis-Tsakonas,et al.  Intracellular Cleavage of Notch Leads to a Heterodimeric Receptor on the Plasma Membrane , 1997, Cell.

[19]  G. Weinmaster,et al.  Notch1 is essential for postimplantation development in mice. , 1994, Genes & development.

[20]  M. Fortini,et al.  The suppressor of hairless protein participates in notch receptor signaling , 1994, Cell.

[21]  B. Trask,et al.  The human homolog of rat Jagged1 expressed by marrow stroma inhibits differentiation of 32D cells through interaction with Notch1. , 1998, Immunity.

[22]  R. Evans,et al.  A histone deacetylase corepressor complex regulates the Notch signal transduction pathway. , 1998, Genes & development.

[23]  David J. Anderson,et al.  Notch signalling controls pancreatic cell differentiation , 1999, Nature.

[24]  C. Murre,et al.  The role of E-proteins in B- and T-lymphocyte development. , 1998, Seminars in immunology.

[25]  S. Artavanis-Tsakonas,et al.  Alterations in Notch signaling in neoplastic lesions of the human cervix. , 1995, Proceedings of the National Academy of Sciences of the United States of America.

[26]  William J. Ray,et al.  A presenilin-1-dependent γ-secretase-like protease mediates release of Notch intracellular domain , 1999, Nature.

[27]  S. Artavanis-Tsakonas,et al.  Notch signaling: cell fate control and signal integration in development. , 1999, Science.

[28]  M. Fortini,et al.  Neurogenic phenotypes and altered Notch processing in Drosophila Presenilin mutants , 1999, Nature.

[29]  Céline Gélinas,et al.  Rel/NF‐κB can trigger the Notch signaling pathway by inducing the expression of Jagged1, a ligand for Notch receptors , 1999, The EMBO journal.

[30]  K. Tomita,et al.  The bHLH gene Hes1 is essential for expansion of early T cell precursors. , 1999, Genes & development.

[31]  F. Oswald,et al.  NF-κB2 Is a Putative Target Gene of Activated Notch-1 via RBP-Jκ , 1998, Molecular and Cellular Biology.

[32]  J. Sklar,et al.  Exclusive development of T cell neoplasms in mice transplanted with bone marrow expressing activated Notch alleles , 1996, The Journal of experimental medicine.

[33]  Suzanne Cory,et al.  bcl-2 transgene inhibits T cell death and perturbs thymic self-censorship , 1991, Cell.

[34]  P. Rakic,et al.  Processing of the notch ligand delta by the metalloprotease Kuzbanian. , 1999, Science.

[35]  J. Hsieh,et al.  Masking of the CBF1/RBPJ kappa transcriptional repression domain by Epstein-Barr virus EBNA2. , 1995, Science.

[36]  S. Artavanis-Tsakonas,et al.  Notch Inhibition of E47 Supports the Existence of a Novel Signaling Pathway , 1998, Molecular and Cellular Biology.

[37]  A. Bigas,et al.  Notch as a mediator of cell fate determination in hematopoiesis: evidence and speculation. , 1999, Blood.

[38]  H. Macdonald,et al.  Deficient T cell fate specification in mice with an induced inactivation of Notch1. , 1999, Immunity.

[39]  H. Weintraub,et al.  The intracellular domain of mouse Notch: a constitutively activated repressor of myogenesis directed at the basic helix-loop-helix region of MyoD. , 1994, Development.

[40]  J. Finke,et al.  Inhibition of NF-κB Activity in Human T Lymphocytes Induces Caspase-Dependent Apoptosis Without Detectable Activation of Caspase-1 and -3 , 1999, The Journal of Immunology.

[41]  J. Boulter,et al.  The Notch/Jagged Pathway Inhibits Proliferation of Human Hematopoietic Progenitors In Vitro , 1999, Stem cells.

[42]  J. Sklar,et al.  Notch1-Induced Delay of Human Hematopoietic Progenitor Cell Differentiation Is Associated With Altered Cell Cycle Kinetics , 1999 .

[43]  N. Tarantino,et al.  In Vivo Inhibition of NF-κB in T-Lineage Cells Leads to a Dramatic Decrease in Cell Proliferation and Cytokine Production and to Increased Cell Apoptosis in Response to Mitogenic Stimuli, But Not to Abnormal Thymopoiesis , 1999, The Journal of Immunology.

[44]  J. Aster,et al.  Notch1 expression in early lymphopoiesis influences B versus T lineage determination. , 1999, Immunity.

[45]  D. Pinkel,et al.  E2A deficiency leads to abnormalities in alphabeta T-cell development and to rapid development of T-cell lymphomas , 1997, Molecular and cellular biology.

[46]  S. Artavanis-Tsakonas,et al.  Human deltex is a conserved regulator of Notch signalling , 1998, Nature Genetics.

[47]  W. Pear,et al.  Cutting edge: protective effects of notch-1 on TCR-induced apoptosis. , 1999, Journal of immunology.

[48]  B. Yankner,et al.  Proteolytic release and nuclear translocation of Notch-1 are induced by presenilin-1 and impaired by pathogenic presenilin-1 mutations. , 1999, Proceedings of the National Academy of Sciences of the United States of America.

[49]  L. Miele,et al.  Notch‐1 inhibits apoptosis in murine erythroleukemia cells and is necessary for differentiation induced by hybrid polar compounds , 1999, Journal of cellular biochemistry.

[50]  H. Kim,et al.  The Notch Pathway Intermediate HES-1 Silences CD4 Gene Expression , 1998, Molecular and Cellular Biology.

[51]  J. Hsieh,et al.  CIR, a corepressor linking the DNA binding factor CBF1 to the histone deacetylase complex. , 1999, Proceedings of the National Academy of Sciences of the United States of America.

[52]  D. Pyatt,et al.  An Essential Role for NF-kB in Human CD34 1 Bone Marrow Cell Survival , 1999 .

[53]  G. Weinmaster,et al.  Defects in limb, craniofacial, and thymic development in Jagged2 mutant mice. , 1998, Genes & development.

[54]  A. Martinez-Arias,et al.  An activity of Notch regulates JNK signalling and affects dorsal closure in Drosophila , 1999, Current Biology.

[55]  S. Korsmeyer,et al.  bcl-2 inhibits multiple forms of apoptosis but not negative selection in thymocytes , 1991, Cell.

[56]  B. Barres,et al.  Notch Receptor Activation Inhibits Oligodendrocyte Differentiation , 1998, Neuron.

[57]  G. Weinmaster,et al.  An Activated Form of Notch Influences the Choice between CD4 and CD8 T Cell Lineages , 1996, Cell.

[58]  G. Mukherjee,et al.  The link between integration and expression of human papillomavirus type 16 genomes and cellular changes in the evolution of cervical intraepithelial neoplastic lesions. , 1997, The Journal of general virology.

[59]  G. Weinmaster,et al.  Embryonic lethality and vascular defects in mice lacking the Notch ligand Jagged1. , 1999, Human molecular genetics.

[60]  C. Murre,et al.  Ectopic expression of E47 or E12 promotes the death of E2A-deficient lymphomas. , 1999, Proceedings of the National Academy of Sciences of the United States of America.

[61]  A Gulino,et al.  Expression pattern of notch1, 2 and 3 and Jagged1 and 2 in lymphoid and stromal thymus components: distinct ligand-receptor interactions in intrathymic T cell development. , 1999, International immunology.

[62]  S. Minoguchi,et al.  Physical interaction between a novel domain of the receptor Notch and the transcription factor RBP-Jκ/Su(H) , 1995, Current Biology.

[63]  Ian Krop,et al.  E2A proteins are required for proper B cell development and initiation of immunoglobulin gene rearrangements , 1994, Cell.

[64]  D. Ward,et al.  Human ligands of the Notch receptor. , 1999, The American journal of pathology.