Prevalence, clonal dynamics and clinical impact of TP53 mutations in patients with myelodysplastic syndrome with isolated deletion (5q) treated with lenalidomide: results from a prospective multicenter study of the german MDS study group (GMDS)
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R. Schlenk | A. Ganser | T. Haferlach | K. Götze | D. Nowak | W. Hofmann | M. Lübbert | U. Germing | A. Giagounidis | U. Platzbecker | G. Büsche | F. Nolte | G. Metzgeroth | M. Mossner | V. Nowak | J. Obländer | D. Haase | A. Letsch | P. Schafhausen | G. Bug | K. Shirneshan | S. Fey | J. Jann | N. Müller | F. Braulke | E. Schuler | E. Lauinger-Lörsch | J. Pressler | C. Weiß
[1] R. Schlenk,et al. Results of a multicenter prospective phase II trial investigating the safety and efficacy of lenalidomide in patients with myelodysplastic syndromes with isolated del(5q) (LE-MON 5) , 2016, Leukemia.
[2] S. Nahas,et al. Impact of TP53 mutation variant allele frequency on phenotype and outcomes in myelodysplastic syndromes , 2016, Leukemia.
[3] G. Mufti,et al. TP53 mutations in myelodysplastic syndrome are strongly correlated with aberrations of chromosome 5, and correlate with adverse prognosis , 2013, British journal of haematology.
[4] A. Glasmacher,et al. Lenalidomide does not increase AML progression risk in RBC transfusion-dependent patients with Low- or Intermediate-1-risk MDS with del(5q): a comparative analysis , 2012, Leukemia.
[5] R. Schlenk,et al. Survival, prognostic factors and rates of leukemic transformation in 381 untreated patients with MDS and del(5q): A multicenter study , 2012, Leukemia.
[6] M. Cazzola,et al. A randomized phase 3 study of lenalidomide versus placebo in RBC transfusion-dependent patients with Low-/Intermediate-1-risk myelodysplastic syndromes with del5q. , 2011, Blood.
[7] Eva Hellström-Lindberg,et al. TP53 mutations in low-risk myelodysplastic syndromes with del(5q) predict disease progression. , 2011, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[8] P. Woll,et al. Persistent malignant stem cells in del(5q) myelodysplasia in remission. , 2010, The New England journal of medicine.
[9] L. Saft,et al. Clonal heterogeneity in the 5q- syndrome: p53 expressing progenitors prevail during lenalidomide treatment and expand at disease progression , 2009, Haematologica.
[10] M. Gordon. Lenalidomide in the Myelodysplastic Syndrome with Chromosome 5q Deletion , 2008 .
[11] M. Gordon. Efficacy of Lenalidomide in Myelodysplastic Syndromes , 2006 .
[12] J. Boultwood,et al. NRAS, FLT3 and TP53 mutations in patients with myelodysplastic syndrome and a del(5q). , 2004, Haematologica.
[13] M. Taniwaki,et al. International prognostic scoring system and TP53 mutations are independent prognostic indicators for patients with myelodysplastic syndrome , 2001, British journal of haematology.
[14] S. Chevret,et al. RAS, FMS and p53 mutations and poor clinical outcome in myelodysplasias: a 10-year follow-up , 1998, Leukemia.
[15] A. Órfão,et al. Indolent systemic mast cell disease in adults: immunophenotypic characterization of bone marrow mast cells and its diagnostic implications. , 1998, Blood.
[16] Koichi Sugimoto,et al. Mutations of the p53 gene in myelodysplastic syndrome (MDS) and MDS-derived leukemia. , 1993, Blood.