Tumor necrosis factor-α-induced nuclear factor-kappaB activation in human cardiomyocytes is mediated by NADPH oxidase

[1]  L. Hsiao,et al.  NADPH oxidase/ROS-dependent PYK2 activation is involved in TNF-α-induced matrix metalloproteinase-9 expression in rat heart-derived H9c2 cells. , 2013, Toxicology and applied pharmacology.

[2]  T. Koh,et al.  Nox2 and Nox4 mediate tumour necrosis factor-α-induced ventricular remodelling in mice , 2011, Journal of cellular and molecular medicine.

[3]  C. Sobey,et al.  Combating oxidative stress in vascular disease: NADPH oxidases as therapeutic targets , 2011, Nature Reviews Drug Discovery.

[4]  L. Kirshenbaum,et al.  Multiple facets of NF-κB in the heart: to be or not to NF-κB. , 2011, Circulation Research.

[5]  Michael J Morgan,et al.  Crosstalk of reactive oxygen species and NF-κB signaling , 2011, Cell Research.

[6]  S. Krobitsch,et al.  Effects of EpCAM overexpression on human breast cancer cell lines , 2011, BMC Cancer.

[7]  Steven J Brown,et al.  A novel and specific NADPH oxidase-1 (Nox1) small-molecule inhibitor blocks the formation of functional invadopodia in human colon cancer cells. , 2010, ACS chemical biology.

[8]  Sophie Houngninou-Molango,et al.  First in class, potent, and orally bioavailable NADPH oxidase isoform 4 (Nox4) inhibitors for the treatment of idiopathic pulmonary fibrosis. , 2010, Journal of medicinal chemistry.

[9]  H. Schmidt,et al.  Comparative pharmacology of chemically distinct NADPH oxidase inhibitors , 2010, British journal of pharmacology.

[10]  Mazhar Adli,et al.  IKKα and IKKβ Each Function to Regulate NF-κB Activation in the TNF-Induced/Canonical Pathway , 2010, PloS one.

[11]  L. Hsu,et al.  Dramatic Co-Activation of WWOX/WOX1 with CREB and NF-κB in Delayed Loss of Small Dorsal Root Ganglion Neurons upon Sciatic Nerve Transection in Rats , 2009, PloS one.

[12]  Claudio M. Martin,et al.  NADPH oxidase contributes to conversion of cardiac myocytes to a proinflammatory phenotype in sepsis. , 2009, Free radical biology & medicine.

[13]  R. O'Connor,et al.  Sequestration of PDLIM2 in the cytoplasm of monocytic/macrophage cells is associated with adhesion and increased nuclear activity of NF‐κB , 2009, Journal of leukocyte biology.

[14]  T. Yue,et al.  Rosiglitazone inhibits hypercholesterolaemia-induced myeloperoxidase upregulation--a novel mechanism for the cardioprotective effects of PPAR agonists. , 2008, Cardiovascular research.

[15]  S. Choudhary,et al.  RelA Ser276 Phosphorylation Is Required for Activation of a Subset of NF-κB-Dependent Genes by Recruiting Cyclin-Dependent Kinase 9/Cyclin T1 Complexes , 2008, Molecular and Cellular Biology.

[16]  S. Ghosh,et al.  Shared Principles in NF-κB Signaling , 2008, Cell.

[17]  R. Busse,et al.  Apocynin Is Not an Inhibitor of Vascular NADPH Oxidases but an Antioxidant , 2008, Hypertension.

[18]  Xin Lin,et al.  Positive and negative signaling components involved in TNFα-induced NF-κB activation , 2008 .

[19]  Xin Lin,et al.  Positive and negative signaling components involved in TNFalpha-induced NF-kappaB activation. , 2008, Cytokine.

[20]  F. DeLeo,et al.  Role of NF‐κB in transcriptional regulation of the phagocyte NADPH oxidase by tumor necrosis factor‐α , 2007 .

[21]  Lie Gao,et al.  NADPH oxidase-derived superoxide anion mediates angiotensin II-enhanced carotid body chemoreceptor sensitivity in heart failure rabbits. , 2007, Cardiovascular research.

[22]  M. S. Galhiane,et al.  The oxidation of apocynin catalyzed by myeloperoxidase: proposal for NADPH oxidase inhibition. , 2007, Archives of biochemistry and biophysics.

[23]  F. DeLeo,et al.  Role of NF-kappaB in transcriptional regulation of the phagocyte NADPH oxidase by tumor necrosis factor-alpha. , 2007, Journal of leukocyte biology.

[24]  G. Franzoso,et al.  Mutual cross-talk between reactive oxygen species and nuclear factor-kappa B: molecular basis and biological significance , 2006, Oncogene.

[25]  K. Eguchi,et al.  DHMEQ, a novel NF-kappaB inhibitor, induces apoptosis and cell-cycle arrest in human hepatoma cells. , 2006, International journal of oncology.

[26]  S. Rosenkranz,et al.  Novel Nox inhibitor VAS2870 attenuates PDGF-dependent smooth muscle cell chemotaxis, but not proliferation. , 2006, Cardiovascular research.

[27]  Rajendra K. Sharma,et al.  TNF-α-mediated cardiomyocyte apoptosis involves caspase-12 and calpain , 2006 .

[28]  Simon J. Walker,et al.  NADPH oxidases in cardiovascular health and disease. , 2006, Antioxidants & redox signaling.

[29]  C. Iadecola,et al.  NF-κB Regulates Phagocytic NADPH Oxidase by Inducing the Expression of gp91phox* , 2006, Journal of Biological Chemistry.

[30]  G. Dusting,et al.  Differential upregulation of Nox homologues of NADPH oxidase by tumor necrosis factor-α in human aortic smooth muscle and embryonic kidney cells , 2006, Journal of cellular and molecular medicine.

[31]  Rajendra K. Sharma,et al.  TNF-alpha-mediated cardiomyocyte apoptosis involves caspase-12 and calpain. , 2006, Biochemical and biophysical research communications.

[32]  C. Iadecola,et al.  NF-kappaB regulates phagocytic NADPH oxidase by inducing the expression of gp91phox. , 2006, The Journal of biological chemistry.

[33]  Jie Du,et al.  Dual Pathways for Nuclear Factor &kgr;B Activation by Angiotensin II in Vascular Smooth Muscle: Phosphorylation of p65 by I&kgr;B Kinase and Ribosomal Kinase , 2005, Circulation research.

[34]  M. Christie,et al.  Acute Tumor Necrosis Factor Alpha Signaling via NADPH Oxidase in Microvascular Endothelial Cells: Role of p47phox Phosphorylation and Binding to TRAF4 , 2005, Molecular and Cellular Biology.

[35]  M. Vetter,et al.  Inhibition of Nox‐4 activity by plumbagin, a plant‐derived bioactive naphthoquinone , 2005, The Journal of pharmacy and pharmacology.

[36]  D. Templeton,et al.  Thiol oxidation of cell signaling proteins: Controlling an apoptotic equilibrium , 2004, Journal of cellular biochemistry.

[37]  D. Harrison,et al.  Shear Stress Regulates Endothelial Nitric-oxide Synthase Promoter Activity through Nuclear Factor κB Binding* , 2004, Journal of Biological Chemistry.

[38]  P. Neumann,et al.  NAD(P)H oxidase mediates the endothelial barrier dysfunction induced by TNF-alpha. , 2004, American journal of physiology. Lung cellular and molecular physiology.

[39]  P. Neumann,et al.  NAD(P)H oxidase mediates the endothelial barrier dysfunction induced by TNF-α , 2004 .

[40]  A. Shah,et al.  Contrasting Roles of NADPH Oxidase Isoforms in Pressure-Overload Versus Angiotensin II–Induced Cardiac Hypertrophy , 2003, Circulation research.

[41]  D. Harrison,et al.  The vascular NAD(P)H oxidases as therapeutic targets in cardiovascular diseases. , 2003, Trends in pharmacological sciences.

[42]  H. Kamata,et al.  Hydrogen peroxide activates IκB kinases through phosphorylation of serine residues in the activation loops , 2002, FEBS letters.

[43]  J. Hoidal,et al.  NADPH oxidase promotes NF-kappaB activation and proliferation in human airway smooth muscle. , 2002, American journal of physiology. Lung cellular and molecular physiology.

[44]  Thomas D. Schmittgen,et al.  Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. , 2001, Methods.

[45]  R. Cohen,et al.  S17834, a New Inhibitor of Cell Adhesion and Atherosclerosis That Targets NADPH Oxidase , 2001, Arteriosclerosis, thrombosis, and vascular biology.

[46]  M. Karin,et al.  Signal transduction by tumor necrosis factor and its relatives. , 2001, Trends in cell biology.

[47]  D. Sawyer,et al.  Reactive Oxygen Species Mediate Amplitude-Dependent Hypertrophic and Apoptotic Responses to Mechanical Stretch in Cardiac Myocytes , 2001, Circulation research.

[48]  R. Beuerman,et al.  Differential expression of glyceraldehyde-3-phosphate dehydrogenase (GAPDH), ß actin and hypoxanthine phosphoribosyltransferase (HPRT) in postnatal rabbit sclera , 2001, Current eye research.

[49]  D. Wagner,et al.  The role of tumor necrosis factor in the pathophysiology of heart failure. , 2000, Journal of the American College of Cardiology.

[50]  X. Fan,et al.  Lysophosphatidic acid activates NF-kappaB in fibroblasts. A requirement for multiple inputs. , 1999, The Journal of biological chemistry.

[51]  Y. Goltsev,et al.  Tumor necrosis factor receptor and Fas signaling mechanisms. , 1999, Annual review of immunology.

[52]  K. Mihara,et al.  Inhibitory effects of antioxidants on neonatal rat cardiac myocyte hypertrophy induced by tumor necrosis factor-alpha and angiotensin II. , 1998, Circulation.

[53]  V. Koshkin,et al.  Inhibition of NADPH Oxidase Activation by 4-(2-Aminoethyl)-benzenesulfonyl Fluoride and Related Compounds* , 1997, The Journal of Biological Chemistry.

[54]  A. Jesaitis,et al.  A Domain of p47phox That Interacts with Human Neutrophil Flavocytochrome b558(*) , 1995, The Journal of Biological Chemistry.

[55]  R. Alexander,et al.  Vascular cell adhesion molecule-1 (VCAM-1) gene transcription and expression are regulated through an antioxidant-sensitive mechanism in human vascular endothelial cells. , 1993, The Journal of clinical investigation.

[56]  J. Hiscott,et al.  Characterization of a functional NF-kappa B site in the human interleukin 1 beta promoter: evidence for a positive autoregulatory loop , 1993, Molecular and cellular biology.

[57]  G. Schieven,et al.  Reactive oxygen intermediates activate NF-kappa B in a tyrosine kinase- dependent mechanism and in combination with vanadate activate the p56lck and p59fyn tyrosine kinases in human lymphocytes , 1993 .

[58]  T. Libermann,et al.  Activation of interleukin-6 gene expression through the NF-kappa B transcription factor , 1990, Molecular and cellular biology.