Nipple-Sparing Mastectomy and Direct-to-Implant Breast Reconstruction

Summary: Breast reconstruction following mastectomy has evolved to preserve the native skin and nipple of the breast and create a natural-appearing reconstruction in 1 or 2 surgeries. Nipple-sparing procedures appear to be oncologically safe with low risks of cancer recurrence. In our series of 2,182 nipple-sparing mastectomies, there was no development or recurrence of cancer in the nipple. Direct-to-implant single-stage surgery offers the patient a complete reconstruction at the time of mastectomy. Patient selection centers on preoperative breast anatomy combined with postoperative goals for size and uplift of the breast. The best candidates for nipple-sparing mastectomy and direct-to-implant breast reconstruction include those with grade I–II breast ptosis and those desiring to stay approximately the same breast size. The choice of incision and width of the implant play key roles in nipple centralization. Partial muscle coverage with acellular dermal matrix remains the most common technique to support the implant and offers the advantage of more soft-tissue coverage in the upper pole. With experience, complications and revisions are similar in this approach compared with more traditional 2-stage tissue expander-implant reconstruction. Thus, nipple-sparing mastectomy and direct-to-implant breast reconstruction is emerging as a preferred method of breast reconstruction when the breast skin envelope is sufficiently perfused.

[1]  Barbara L. Smith,et al.  Oncologic Safety of Nipple-Sparing Mastectomy in Women with Breast Cancer. , 2017, Journal of the American College of Surgeons.

[2]  G. Zoccali,et al.  Outcome Evaluation after 2023 Nipple-Sparing Mastectomies: Our Experience , 2017, Plastic and reconstructive surgery.

[3]  Briar L. Dent,et al.  Tumor-to-Nipple Distance as a Predictor of Nipple Involvement: Expanding the Inclusion Criteria for Nipple-Sparing Mastectomy , 2017, Plastic and reconstructive surgery.

[4]  J. Frey,et al.  Comparison of Outcomes with Tissue Expander, Immediate Implant, and Autologous Breast Reconstruction in Greater Than 1000 Nipple-Sparing Mastectomies , 2017, Plastic and reconstructive surgery.

[5]  L. Medeiros,et al.  Global Adverse Event Reports of Breast Implant–Associated ALCL: An International Review of 40 Government Authority Databases , 2017, Plastic and reconstructive surgery.

[6]  Barbara L. Smith,et al.  Nipple Loss following Nipple-Sparing Mastectomy. , 2016, Plastic and reconstructive surgery.

[7]  A. Colwell,et al.  Revisions in Implant-Based Breast Reconstruction: How Does Direct-to-Implant Measure Up? , 2016, Plastic and reconstructive surgery.

[8]  Barbara L. Smith,et al.  Nipple-Sparing Mastectomy in Patients with Previous Breast Surgery: Comparative Analysis of 775 Immediate Breast Reconstructions , 2015, Plastic and reconstructive surgery.

[9]  M. Alperovich,et al.  Nipple-Sparing Mastectomy in Patients with Prior Breast Irradiation: Are Patients at Higher Risk for Reconstructive Complications? , 2014, Plastic and reconstructive surgery.

[10]  M. Scheflan,et al.  Tissue Reinforcement in Implant-based Breast Reconstruction , 2014, Plastic and reconstructive surgery. Global open.

[11]  Barbara L. Smith,et al.  Breast Reconstruction Outcomes after Nipple-Sparing Mastectomy and Radiation Therapy , 2014, Plastic and reconstructive surgery.

[12]  Barbara L. Smith,et al.  Breast Reconstruction following Nipple-Sparing Mastectomy: Predictors of Complications, Reconstruction Outcomes, and 5-Year Trends , 2014, Plastic and reconstructive surgery.

[13]  Phoebe E. Freer,et al.  Increasing Eligibility for Nipple-Sparing Mastectomy , 2013, Annals of Surgical Oncology.

[14]  Jennifer H. Lin,et al.  Surgical Delay of the Nipple–Areolar Complex: A Powerful Technique to Maximize Nipple Viability Following Nipple-Sparing Mastectomy , 2012, Annals of Surgical Oncology.

[15]  S. Spear,et al.  Breast Reconstruction Using a Staged Nipple-Sparing Mastectomy following Mastopexy or Reduction , 2012, Plastic and reconstructive surgery.

[16]  A. Colwell,et al.  Retrospective Review of 331 Consecutive Immediate Single-Stage Implant Reconstructions with Acellular Dermal Matrix: Indications, Complications, Trends, and Costs , 2011, Plastic and reconstructive surgery.

[17]  A. Ashikari,et al.  An 8-Year Experience of Direct-to-Implant Immediate Breast Reconstruction Using Human Acellular Dermal Matrix (AlloDerm) , 2011, Plastic and reconstructive surgery.

[18]  Barbara L. Smith,et al.  An Inferolateral Approach to Nipple-Sparing Mastectomy: Optimizing Mastectomy and Reconstruction , 2010, Annals of plastic surgery.

[19]  Barbara L. Smith,et al.  George Peters Award. Microscopic anatomy within the nipple: implications for nipple-sparing mastectomy. , 2007, American journal of surgery.

[20]  A. Colwell,et al.  Inferolateral AlloDerm Hammock for Implant Coverage in Breast Reconstruction , 2007, Annals of plastic surgery.