Grating-based surface plasmon resonance detection of core-shell nanoparticle mediated DNA hybridization.

In this report, we have investigated enhanced surface plasmon resonance (SPR) detection of DNA hybridization using gold core - silica shell nanoparticles in localized plasmonic fields. The plasmonic fields were localized by periodic linear gratings. Experimental results measured for hybridization of 24-mer single-stranded DNA oligomers suggest that core-shell nanoparticles (CSNPs) on gratings of 400 nm period provide enhanced optical signatures by 36 times over conventional thin film-based SPR detection. CSNP-mediated DNA hybridization produced 3 times larger angular shift compared to gold nanoparticles of the same core size. We have also analyzed the effect of structural variation. The enhancement using CSNPs was associated with increased surface area and index contrast that is combined by improved plasmon coupling with localized fields on gratings. The combined approach for conjugated measurement of a biomolecular interaction on grating structures is expected to lower the limit of detection to the order of a few tens of fg/mm(2).

[1]  N. Halas,et al.  Nano-optics from sensing to waveguiding , 2007 .

[2]  Yang Li,et al.  Detection of picomolar levels of interleukin-8 in human saliva by SPR. , 2005, Lab on a chip.

[3]  A. Libchaber,et al.  Single-mismatch detection using gold-quenched fluorescent oligonucleotides , 2001, Nature Biotechnology.

[4]  R. Karlsson,et al.  SPR for molecular interaction analysis: a review of emerging application areas , 2004, Journal of molecular recognition : JMR.

[5]  Daeha Seo,et al.  Polyhedral gold nanocrystals with O h symmetry: from octahedra to cubes. , 2006, Journal of the American Chemical Society.

[6]  T. Chinowsky,et al.  Quantitative interpretation of the response of surface plasmon resonance sensors to adsorbed films , 1998 .

[7]  Jun‐Hyun Kim,et al.  Preparation, characterization, and optical properties of gold, silver, and gold-silver alloy nanoshells having silica cores. , 2008, Langmuir : the ACS journal of surfaces and colloids.

[8]  L. Liz‐Marzán,et al.  Quantitative determination of the size dependence of surface plasmon resonance damping in single Ag@SiO(2) nanoparticles. , 2009, Nano letters.

[9]  Mikael Käll,et al.  Refractometric sensing using propagating versus localized surface plasmons: a direct comparison. , 2009, Nano letters.

[10]  Kazuhiro Hane,et al.  100 nm period silicon antireflection structures fabricated using a porous alumina membrane mask , 2001 .

[11]  Donghyun Kim,et al.  Design study of highly sensitive nanowire-enhanced surface plasmon resonance biosensors using rigorous coupled wave analysis. , 2005, Optics express.

[12]  Sergiy Patskovsky,et al.  Phase and amplitude sensitivities in surface plasmon resonance bio and chemical sensing. , 2009, Optics express.

[13]  D. Roper.  Determining Surface Plasmon Resonance Response Factors for Deposition onto Three-Dimensional Surfaces. , 2007, Chemical engineering science.

[14]  B. Liedberg,et al.  Principles of biosensing with an extended coupling matrix and surface plasmon resonance , 1993 .

[15]  M. El-Sayed,et al.  Why gold nanoparticles are more precious than pretty gold: noble metal surface plasmon resonance and its enhancement of the radiative and nonradiative properties of nanocrystals of different shapes. , 2006, Chemical Society reviews.

[16]  D. Lynch,et al.  Handbook of Optical Constants of Solids , 1985 .

[17]  Kyujung Kim,et al.  Surface-enhanced plasmon resonance detection of nanoparticle-conjugated DNA hybridization. , 2010, Applied optics.

[18]  Donghyun Kim,et al.  Colocalization of gold nanoparticle-conjugated DNA hybridization for enhanced surface plasmon detection using nanograting antennas. , 2011, Optics letters.

[19]  Gibum Kim,et al.  SPR microscopy and its applications to high-throughput analyses of biomolecular binding events and their kinetics. , 2007, Biomaterials.

[20]  Tatsuro Endo,et al.  Multiple label-free detection of antigen-antibody reaction using localized surface plasmon resonance-based core-shell structured nanoparticle layer nanochip. , 2006, Analytical chemistry.

[21]  P. Quémerais,et al.  Why metallic surfaces with grooves a few nanometers deep and wide may strongly absorb visible light. , 2007, Physical review letters.

[22]  R. V. Van Duyne,et al.  Localized surface plasmon resonance spectroscopy and sensing. , 2007, Annual review of physical chemistry.

[23]  Mikael Käll,et al.  Plasmon-enhanced colorimetric ELISA with single molecule sensitivity. , 2011, Nano letters.

[24]  Romain Quidant,et al.  Electromagnetic coupling between a metal nanoparticle grating and a metallic surface. , 2005, Optics letters.

[25]  Peter Nordlander,et al.  Unidirectional broadband light emission from supported plasmonic nanowires. , 2011, Nano letters.

[26]  Hua-Lin Wu,et al.  Study of cell-biosubstrate contacts via surface plasmon polariton phase microscopy. , 2010, Optics express.

[27]  Philippe Lalanne,et al.  Interaction between optical nano-objects at metallo-dielectric interfaces , 2006 .

[28]  Younan Xia,et al.  Localized surface plasmon resonance spectroscopy of single silver nanocubes. , 2005, Nano letters.

[29]  Lin He,et al.  Colloidal Au-Enhanced Surface Plasmon Resonance for Ultrasensitive Detection of DNA Hybridization , 2000 .

[30]  P. Yang,et al.  Crystal Growth , 2004 .

[31]  B Cui,et al.  Enhanced surface plasmon resonance imaging detection of DNA hybridization on periodic gold nanoposts. , 2007, Optics letters.

[32]  Donghyun Kim,et al.  Surface plasmon resonance phase imaging measurements of patterned monolayers and DNA adsorption onto microarrays. , 2011, Analytical chemistry.

[33]  Jeffrey N. Anker,et al.  Biosensing with plasmonic nanosensors. , 2008, Nature materials.

[34]  D. Meisel,et al.  Adsorption and surface-enhanced Raman of dyes on silver and gold sols , 1982 .

[35]  Kyujung Kim,et al.  Target-Localized Nanograting-Based Surface Plasmon Resonance Detection toward Label-free Molecular Biosensing , 2010, IEEE Journal of Selected Topics in Quantum Electronics.

[36]  Donghyun Kim,et al.  Effect of target localization on the sensitivity of a localized surface plasmon resonance biosensor based on subwavelength metallic nanostructures. , 2009, Journal of the Optical Society of America. A, Optics, image science, and vision.

[37]  Paul Mulvaney,et al.  Synthesis of Nanosized Gold−Silica Core−Shell Particles , 1996 .

[38]  P. Nordlander,et al.  A Hybridization Model for the Plasmon Response of Complex Nanostructures , 2003, Science.

[39]  N. Halas,et al.  Metallic nanoshells with semiconductor cores: optical characteristics modified by core medium properties. , 2010, ACS nano.

[40]  Seokmin Shin,et al.  Adsorption of 4-Biphenylmethanethiolate on Different-Sized Gold Nanoparticle Surfaces , 2004 .

[41]  Ibrahim Abdulhalim,et al.  Electromagnetic fields distribution in multilayer thin film structures and the origin of sensitivity enhancement in surface plasmon resonance sensors , 2010 .

[42]  J. Homola,et al.  Surface plasmon resonance (SPR) sensors: approaching their limits? , 2009, Optics express.

[43]  P. Jain,et al.  Universal scaling of plasmon coupling in metal nanostructures: extension from particle pairs to nanoshells. , 2007, Nano letters.

[44]  X. D. Hoa,et al.  Enhanced SPR response from patterned immobilization of surface bioreceptors on nano-gratings. , 2009, Biosensors & bioelectronics.

[45]  Lloyd M. Smith,et al.  In Situ Surface Plasmon Resonance Imaging Detection of DNA Hybridization to Oligonucleotide Arrays on Gold Surfaces , 1997 .

[46]  Chinlon Lin,et al.  Highly sensitive differential phase-sensitive surface plasmon resonance biosensor based on the Mach-Zehnder configuration. , 2004, Optics letters.

[47]  Kyujung Kim,et al.  Nanowire-based enhancement of localized surface plasmon resonance for highly sensitive detection: a theoretical study. , 2006, Optics express.

[48]  Emil Prodan,et al.  Plasmon Hybridization in Nanoparticles near Metallic Surfaces , 2004 .

[49]  Younan Xia,et al.  Synthesis and Self-Assembly of Au@SiO2 Core−Shell Colloids , 2002 .

[50]  Selim Elhadj,et al.  Optical properties of an immobilized DNA monolayer from 255 to 700 nm. , 2004, Langmuir : the ACS journal of surfaces and colloids.

[51]  S. Yoon,et al.  Experimental study of sensitivity enhancement in surface plasmon resonance biosensors by use of periodic metallic nanowires. , 2007, Optics letters.