Bioactive ceramics: the effect of surface reactivity on bone formation and bone cell function.

Surface reactivity is one of the common characteristics of bone bioactive ceramics. It contributes to their bone bonding ability and their enhancing effect on bone tissue formation. During implantation, reactions occur at the material-tissue interface that lead to time-dependent changes in the surface characteristics of the implant material and the tissues at the interface. This review describes some of the current concepts regarding the surface reactivity of bone bioactive materials and its effect on attachment, proliferation, differentiation and mineralization of bone cells.

[1]  A. Reddi,et al.  Tissue engineering, morphogenesis, and regeneration of the periodontal tissues by bone morphogenetic proteins. , 1997, Critical reviews in oral biology and medicine : an official publication of the American Association of Oral Biologists.

[2]  P. Ducheyne,et al.  Bioactive glass serves as a substrate for maintenance of phenotype of nucleus pulposus cells of the intervertebral disc. , 2000, Journal of biomedical materials research.

[3]  T Kitsugi,et al.  Solutions able to reproduce in vivo surface-structure changes in bioactive glass-ceramic A-W. , 1990, Journal of biomedical materials research.

[4]  P. Ducheyne,et al.  Formation of surface reaction products on bioactive glass and their effects on the expression of the osteoblastic phenotype and the deposition of mineralized extracellular matrix. , 1997, Biomaterials.

[5]  Klaas de Groot,et al.  Bioceramics of Calcium Phosphate , 2017 .

[6]  C. G. Groot,et al.  Histological and biochemical evaluation of osteoblasts cultured on bioactive glass, hydroxylapatite, titanium alloy, and stainless steel. , 1993, Journal of biomedical materials research.

[7]  A. Caplan,et al.  Osteogenesis in Marrow-Derived Mesenchymal Cell Porous Ceramic Composites Transplanted Subcutaneously: Effect of Fibronectin and Laminin on Cell Retention and Rate of Osteogenic Expression , 1992, Cell transplantation.

[8]  Paul Ducheyne,et al.  Bioceramics: material characteristics versus in vivo behavior. , 1987, Journal of biomedical materials research.

[9]  K. Nakanishi,et al.  Apatite formation on silica gel in simulated body fluid: its dependence on structures of silica gels prepared in different media. , 1996, Journal of biomedical materials research.

[10]  C. V. van Blitterswijk,et al.  The bone-bonding polymer Polyactive 80/20 induces hydroxycarbonate apatite formation in vitro. , 1997, Journal of biomedical materials research.

[11]  J. Weinstein,et al.  Long-term Follow-up of Lower Lumbar Fusion Patients , 1987, Spine.

[12]  C. V. van Blitterswijk,et al.  Structural arrangements at the interface between plasma sprayed calcium phosphates and bone. , 1994, Biomaterials.

[13]  P. Ducheyne,et al.  Effect of hydroxyapatite impregnation on skeletal bonding of porous coated implants. , 1980, Journal of biomedical materials research.

[14]  C. G. Groot,et al.  Behaviour of fetal rat osteoblasts cultured in vitro on bioactive glass and nonreactive glasses. , 1992, Biomaterials.

[15]  S. Radin,et al.  Effect of calcium phosphate coating characteristics on early post-operative bone tissue ingrowth. , 1990, Biomaterials.

[16]  V. Goldberg,et al.  The origin of bone formed in composite grafts of porous calcium phosphate ceramic loaded with marrow cells. , 1991, Clinical orthopaedics and related research.

[17]  B. Riggs,et al.  Zeolite a increases proliferation, differentiation, and transforming growth factor β production in normal adult human osteoblast‐like cells in vitro , 1992, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[18]  M. Urist.  Bone: Formation by Autoinduction , 1965, Science.

[19]  T. Yamamuro,et al.  Bonding behavior between two bioactive ceramics in vivo. , 1987, Journal of biomedical materials research.

[20]  C. Klein,et al.  Biodegradation behavior of various calcium phosphate materials in bone tissue. , 1983, Journal of biomedical materials research.

[21]  B Kerebel,et al.  Transformation of biphasic calcium phosphate ceramics in vivo: ultrastructural and physicochemical characterization. , 1989, Journal of biomedical materials research.

[22]  S Tamai,et al.  Marrow cell induced osteogenesis in porous hydroxyapatite and tricalcium phosphate: a comparative histomorphometric study of ectopic bone formation. , 1990, Journal of biomedical materials research.

[23]  A. Clark,et al.  Calcium phosphate formation on sol-gel-derived bioactive glasses in vitro. , 1994, Journal of biomedical materials research.

[24]  X. Zhang,et al.  Osseous substance formation induced in porous calcium phosphate ceramics in soft tissues. , 1994, Biomaterials.

[25]  V. Goldberg,et al.  Heterotopic osteogenesis in porous ceramics induced by marrow cells , 1989, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

[26]  R Z LeGeros,et al.  Calcium Phosphate Materials in Restorative Dentistry: a Review , 1988, Advances in dental research.

[27]  S. Radin,et al.  In vitro release kinetics of biologically active transforming growth factor-β1 from a novel porous glass carrier , 1997 .

[28]  K Nakanishi,et al.  The role of hydrated silica, titania, and alumina in inducing apatite on implants. , 1994, Journal of biomedical materials research.

[29]  U. Ripamonti.  Osteoinduction in porous hydroxyapatite implanted in heterotopic sites of different animal models. , 1996, Biomaterials.

[30]  P Ducheyne,et al.  Bioactive glass particulate material as a filler for bone lesions. , 2008, Journal of oral rehabilitation.

[31]  W. Vogel,et al.  Interface reactions between machinable bioactive glass-ceramics and bone. , 1985, Journal of biomedical materials research.

[32]  I Bab,et al.  The ultrastructure of the interface between a glass ceramic and bone. , 1981, Journal of biomedical materials research.

[33]  P. Ducheyne,et al.  Bioactive material template for in vitro synthesis of bone. , 1995, Journal of biomedical materials research.

[34]  Larry L. Hench,et al.  Bonding mechanisms at the interface of ceramic prosthetic materials , 1971 .

[35]  J. Galante,et al.  Calcium phosphate-coated porous titanium implants for enhanced skeletal fixation. , 1988, Journal of biomedical materials research.

[36]  P. Ducheyne,et al.  BIOACTIVE GLASS PARTICLES OF NARROW SIZE RANGE: A NEW MATERIAL FOR THE REPAIR OF BONE DEFECTS , 1993, Implant dentistry.

[37]  S. Radin,et al.  Transformation of bioactive glass granules into Ca-P shells in vitro , 1997 .

[38]  A. Tencer,et al.  Significance of the Porosity and Physical Chemistry of Calcium Phosphate Ceramics , 1988, Annals of the New York Academy of Sciences.

[39]  P. Ducheyne,et al.  Porous bioactive glass and hydroxyapatite ceramic affect bone cell function in vitro along different time lines. , 1997, Journal of biomedical materials research.

[40]  C. G. Groot,et al.  Better histology and biochemistry for osteoblasts cultured on titanium-doped bioactive glass: bioglass 45S5 compared with iron-, titanium-, fluorine- and boron-containing bioactive glasses. , 1994, Biomaterials.

[41]  P. Ducheyne,et al.  Interfacial analysis of fiber-reinforced bioactive glass dental root implants. , 1989, Journal of biomedical materials research.

[42]  Mclaughlin Re,et al.  Enhanced stabilization of porous-coated metal implants with tricalcium phosphate granules. , 1987 .

[43]  U. Ripamonti,et al.  The morphogenesis of bone in replicas of porous hydroxyapatite obtained from conversion of calcium carbonate exoskeletons of coral. , 1991, The Journal of bone and joint surgery. American volume.

[44]  C. Brighton,et al.  Proliferation and macromolecular synthesis by rat calvarial bone cells grown in various oxygen tensions , 1991, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

[45]  S. Radin,et al.  Sol-gel derived carrier for the controlled release of proteins. , 1999, Biomaterials.

[46]  P. Ducheyne,et al.  Quasi-biological apatite film induced by titanium in a simulated body fluid. , 1998, Journal of biomedical materials research.

[47]  S. Furner,et al.  Musculoskeletal Conditions in the United States , 1992 .

[48]  Larry L. Hench,et al.  Biomaterials : an interfacial approach , 1982 .

[49]  Larry L. Hench,et al.  Bioceramics: From Concept to Clinic , 1991 .

[50]  P. Ducheyne,et al.  Numerical analysis of extracellular fluid flow and chemical species transport around and within porous bioactive glass. , 1994, Journal of biomedical materials research.

[51]  C J Damien,et al.  Bone graft and bone graft substitutes: a review of current technology and applications. , 1991, Journal of applied biomaterials : an official journal of the Society for Biomaterials.

[52]  G. H. Nancollas,et al.  6. Kinetics of Mineralization, Demineralization, and Transformation of Calcium Phosphates at Mineral and Protein Surfaces , 1991 .

[53]  I. Kangasniemi,et al.  Calcium phosphate formation at the surface of bioactive glass in vitro. , 1990, Journal of biomedical materials research.

[54]  P. Ducheyne,et al.  Effect of serum proteins on osteoblast adhesion to surface‐modified bioactive glass and hydroxyapatite , 1999, Journal of Orthopaedic Research.

[55]  I. Orly,et al.  The influence of calcium phosphate biomaterials on human bone cell activities. An in vitro approach. , 1990, Journal of biomedical materials research.

[56]  S. Radin,et al.  The effect of in vitro modeling conditions on the surface reactions of bioactive glass. , 1997, Journal of biomedical materials research.

[57]  S. Downes,et al.  Growth-hormone loaded bioactive ceramics , 1991 .

[58]  S. Radin,et al.  The effect of calcium phosphate ceramic composition and structure on in vitro behavior. I. Dissolution. , 1993, Journal of biomedical materials research.

[59]  K. Nakanishi,et al.  Induction and morphology of hydroxyapatite, precipitated from metastable simulated body fluids on sol-gel prepared silica. , 1993, Biomaterials.

[60]  F. Grinnell,et al.  Adsorption characteristics of plasma fibronectin in relationship to biological activity. , 1981, Journal of biomedical materials research.

[61]  K. de Groot,et al.  Calcium phosphate formation within sol-gel prepared titania in vitro and in vivo. , 1993, Journal of biomedical materials research.

[62]  M. Brown,et al.  Bone transplantation and human immunodeficiency virus. An estimate of risk of acquired immunodeficiency syndrome (AIDS). , 1989, Clinical orthopaedics and related research.

[63]  S. Pollack,et al.  The effect of phase differences on the time-dependent variation of the zeta potential of hydroxyapatite. , 1992, Journal of biomedical materials research.

[64]  T. Yamamuro,et al.  The influence of calcium phosphate ceramics and glass-ceramics on cultured cells and their surrounding media. , 1989, Journal of biomedical materials research.

[65]  V. Goldberg,et al.  Culture-expanded periosteal-derived cells exhibit osteochondrogenic potential in porous calcium phosphate ceramics in vivo. , 1992, Clinical orthopaedics and related research.

[66]  S. Radin,et al.  In vitro transformation of bioactive glass granules into Ca-P shells. , 2000, Journal of biomedical materials research.

[67]  H. Oonishi,et al.  The effect of hydroxyapatite coating on bone growth into porous titanium alloy implants. , 1989, The Journal of bone and joint surgery. British volume.

[68]  S D Cook,et al.  Hydroxyapatite-coated porous titanium for use as an orthopedic biologic attachment system. , 1988, Clinical orthopaedics and related research.

[69]  T. Furusawa,et al.  OSTEOCONDUCTIVE PROPERTIES AND EFFICACY OF RESORBABLE BIOACTIVE GLASS AS A BONE‐GRAFTING MATERIAL , 1997, Implant dentistry.

[70]  R. Doremus,et al.  Tissue, cellular and subcellular events at a bone-ceramic hydroxylapatite interface. , 1977, Journal of bioengineering.

[71]  M. Dunn,et al.  In vitro evaluation of amorphous calcium phosphate and poorly crystallized hydroxyapatite coatings on titanium implants. , 1993, Journal of biomedical materials research.

[72]  L L Hench,et al.  An investigation of bioactive glass powders by sol-gel processing. , 1991, Journal of applied biomaterials : an official journal of the Society for Biomaterials.

[73]  S. Radin,et al.  Si-Ca-P xerogels and bone morphogenetic protein act synergistically on rat stromal marrow cell differentiation in vitro. , 1998, Journal of biomedical materials research.

[74]  T Kitsugi,et al.  Ca,P-rich layer formed on high-strength bioactive glass-ceramic A-W. , 1990, Journal of biomedical materials research.

[75]  S. Radin,et al.  Effect of serum proteins on solution-induced surface transformations of bioactive ceramics. , 1996, Journal of biomedical materials research.

[76]  J. Ricci,et al.  Evaluation of a low-temperature calcium phosphate particulate implant material: physical-chemical properties and in vivo bone response. , 1992, Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons.

[77]  S. Low,et al.  Bioactive ceramics for periodontal treatment: comparative studies in the Patus monkey. , 1992, Journal of applied biomaterials : an official journal of the Society for Biomaterials.

[78]  P. Ducheyne,et al.  Bioactive glass particles of narrow size range for the treatment of oral bone defects: a 1-24 month experiment with several materials and particle sizes and size ranges. , 1997, Journal of oral rehabilitation.

[79]  J. Davies,et al.  Bone Interfaces with Retrieved Alumina and Hydroxyapatite Ceramics , 1991 .

[80]  G. Daculsi,et al.  Macroporous calcium phosphate ceramic for long bone surgery in humans and dogs. Clinical and histological study. , 1990, Journal of biomedical materials research.

[81]  J. S. Skraba,et al.  Use of tricalcium phosphate or electrical stimulation to enhance the bone-porous implant interface. , 1986, Journal of biomedical materials research.

[82]  S. Radin,et al.  Effect of bioactive ceramic composition and structure on in vitro behavior. III. Porous versus dense ceramics. , 1994, Journal of biomedical materials research.

[83]  C. Brighton,et al.  Response of cultured bone cells to a capacitively coupled electric field: Inhibition of cAMP response to parathyroid hormone , 1988, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

[84]  R. Doremus,et al.  Direct electron microscopy studies of the bone-hydroxylapatite interface. , 1984, Journal of biomedical materials research.

[85]  T. Matsuda,et al.  The in vitro response of osteoblasts to bioactive glass. , 1987, Biomaterials.

[86]  P. Brown,et al.  Formation of hydroxyapatite in serum , 1994 .

[87]  P Ducheyne,et al.  Effect of surface reaction stage on fibronectin-mediated adhesion of osteoblast-like cells to bioactive glass. , 1998, Journal of biomedical materials research.