Crystal structure of yeast tRNAAsp

Two independent, three-dimensional structures of yeast tRNAAsp, mainly differing by the conformation of the D loop, have been obtained from a multiple isomorphous replacement (MIR) X-ray analysis at 3.5-Å resolution. The folding of the ribose–phosphate backbone is similar to that found for tRNAphe; major differences concern the relative positioning of the acceptor and anticodon stems, and the conformation of the loops in the two molecules. Crystal packing involves self-complementary GUC anticodon interactions.

[1]  J. Ebel,et al.  Structure of aspartate-tRNA from brewer's yeast. , 1971, Nature: New biology.

[2]  A Klug,et al.  A crystallographic study of metal-binding to yeast phenylalanine transfer RNA. , 1977, Journal of molecular biology.

[3]  B. Roe,et al.  Three-dimensional structure of Escherichia coli initiator tRNAfMet , 1980, Nature.

[4]  J L Sussman,et al.  Crystal structure of yeast phenylalanine transfer RNA. I. Crystallographic refinement. , 1978, Journal of molecular biology.

[5]  J. Gangloff,et al.  Conformational transitions in tRNA Asp (brewer's yeast). Thermodynamic, kinetic, and enzymatic measurements on oligonucleotide fragments and the intact molecule. , 1974, Biochemistry.

[6]  A study of secondary and tertiary solution structure of yeast tRNA(Asp) by nuclear magnetic resonance. Assignment of G.U ring NH and hydrogen-bonded base pair proton resonances. , 1976, Biochemistry.

[7]  D. Crothers,et al.  On the physical basis for ambiguity in genetic coding interactions. , 1978, Proceedings of the National Academy of Sciences of the United States of America.

[8]  J. Lefèvre,et al.  Fluorimetric Study of the Complex between Yeast Phenylalanyl‐tRNA Synthetase and tRNAPhe , 1980 .

[9]  M. Levitt.  Detailed Molecular Model for Transfer Ribonucleic Acid , 1969, Nature.

[10]  U. Schwarz,et al.  Codon-dependent rearrangement of the three-dimensional structure of phenylalanine tRNA, exposing the T-psi-C-G sequence for binding to the 50S ribosomal subunit. , 1976, Biochemistry.

[11]  R Giegé,et al.  Factors determining the specificity of the tRNA aminoacylation reaction. Non-absolute specificity of tRNA-aminoacyl-tRNA synthetase recognition and particular importance of the maximal velocity. , 1973, Biochimie.

[12]  A. Klug,et al.  Crystallographic refinement of yeast phenylalanine transfer RNA at 2-5A resolution. , 1976, Journal of molecular biology.

[13]  A. Rich,et al.  Structural analysis of spermine and magnesium ion binding to yeast phenylalanine transfer RNA. , 1978, Proceedings of the National Academy of Sciences of the United States of America.

[14]  J L Sussman,et al.  Crystal structure of yeast phenylalanine transfer RNA. II. Structural features and functional implications. , 1978, Journal of molecular biology.

[15]  J. Sussman,et al.  Crystal structure of a eukaryotic initiator tRNA , 1979, Nature.

[16]  R. M. Sawicki,et al.  Diagnosis of Resistance to Organophosphorus Insecticides in Myzus persicae (Sulz.) , 1971, Nature.

[17]  R. Giegé,et al.  Yeast transfer RNAasp: a new high-resolution x-ray diffracting crystal form of a transfer RNA. , 1977, Journal of molecular biology.

[18]  D. Crothers,et al.  Is there a discriminator site in transfer RNA? , 1972, Proceedings of the National Academy of Sciences of the United States of America.

[19]  B. Clark,et al.  Structure of yeast phenylalanine tRNA at 3 Å resolution , 1974, Nature.

[20]  M. Sundaralingam,et al.  Crystal and molecular structure of yeast phenylalanyl transfer RNA. Structure determination, difference Fourier refinement, molecular conformation, metal and solvent binding , 1978 .