Hydrogel lens wettability and deposition in vivo

Background: Wearing a hydrogel contact lens disrupts tear film stability, resulting in a low non‐invasive surface drying time (NISDT) on the lens front surface. Reduced wettability causes deposit formation, reducing the quality of vision and lens comfort. This investigation determined the effect of commercially available HEMA‐based materials on pre‐lens tear film stability and deposition.

[1]  M. Guillon,et al.  Preocular Tear Film Characteristics of Nonwearers and Soft Contact Lens Wearers , 1997, Optometry and vision science : official publication of the American Academy of Optometry.

[2]  B. Tighe,et al.  Lipid and protein deposition of N-vinyl pyrrolidone-containing group II and group IV frequent replacement contact lenses. , 1997, The CLAO journal : official publication of the Contact Lens Association of Ophthalmologists, Inc.

[3]  B. Milthorpe,et al.  Human serum albumin adsorption on hydrogel contact lenses in vitro. , 1996, Investigative ophthalmology & visual science.

[4]  M. Guillon,et al.  Clinical management of regular replacement: Part I. Selection of replacement frequency , 1992 .

[5]  M. Refojo,et al.  Attachment of Pseudomonas to Human-Worn, Disposable Etafilcon A Contact Lenses , 1992, Cornea.

[6]  E. Faber,et al.  Effect of Hydrogel Lens Wear on Tear Film Stability , 1991, Optometry and vision science : official publication of the American Academy of Optometry.

[7]  N. Efron,et al.  Characteristics of the pre‐lens tear film during hydrogel contact lens wear , 1991, Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians.

[8]  M. Baines,et al.  Adsorption and Removal of Protein Bound to Hydrogel Contact Lenses , 1990, Optometry and vision science : official publication of the American Academy of Optometry.

[9]  M. Guillon,et al.  Hydrogel lens wettability during overnight wear , 1989, Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians.

[10]  S. Cooper,et al.  Protein adsorption on polymeric biomaterials: II. Adsorption kinetics , 1988 .

[11]  B. Ratner,et al.  Adsorption of proteins from artificial tear solutions to contact lens materials. , 1988, Investigative Ophthalmology and Visual Science.

[12]  R. Sack,et al.  Specificity and biological activity of the protein deposited on the hydrogel surface. Relationship of polymer structure to biofilm formation. , 1987, Investigative ophthalmology & visual science.

[13]  J. Anderson,et al.  Surface modification of soft contact lenses: silanization, wettability and lysozyme adsorption studies. , 1986, Biomaterials.

[14]  R. Sack,et al.  Origin and composition of lipid deposits on soft contact lenses. , 1986, Ophthalmology.

[15]  Lupica Vp Contact lens deposits. , 1984 .

[16]  B. Holden Waterworth Memorial Lecture: THE PRESENT AND FUTURE OF CONTACT LENSES* , 1973 .

[17]  R. Mandell,et al.  Protein accumulation on disposable extended wear lenses. , 1991, The CLAO journal : official publication of the Contact Lens Association of Ophthalmologists, Inc.

[18]  C. McMonnies SURFACE DEPOSIT THEORY AND PRACTICE , 1991 .

[19]  Tripathi Rc,et al.  Physicochemical changes in contact lenses and their interactions with the cornea and tears: a review and personal observations. , 1988 .

[20]  V. Lupica Contact lens deposits. , 1984, Journal of the American Optometric Association.