Variation in the miRNA-433 binding site of FGF20 confers risk for Parkinson disease by overexpression of alpha-synuclein.
暂无分享,去创建一个
Gaofeng Wang | J. M. van der Walt | G. Mayhew | Yi-Ju Li | S. Züchner | W. Scott | E. Martin | J. Vance | W. Scott
[1] Andrew B West,et al. Molecular pathophysiology of Parkinson's disease. , 2005, Annual review of neuroscience.
[2] Gonçalo R. Abecasis,et al. GOLD-Graphical Overview of Linkage Disequilibrium , 2000, Bioinform..
[3] Eden R Martin,et al. Fibroblast growth factor 20 polymorphisms and haplotypes strongly influence risk of Parkinson disease. , 2004, American journal of human genetics.
[4] Murat Gunel,et al. Sequence Variants in SLITRK1 Are Associated with Tourette's Syndrome , 2005, Science.
[5] Robert L. Nussbaum,et al. Mutation in the α-Synuclein Gene Identified in Families with Parkinson's Disease , 1997 .
[6] E R Martin,et al. Letter to the Editor Correcting for a Potential Bias in the Pedigree Disequilibrium Test , 2022 .
[7] Philippe Amouyel,et al. Alpha-synuclein locus duplication as a cause of familial Parkinson's disease. , 2004, Lancet.
[8] S. Omachi. FGF-20, a novel neurotrophic factor, preferentially expressed in the substantia nigra pars compacta of rat brain , 2000 .
[9] L. Stefanis,et al. Regulation of α‐synuclein by bFGF in cultured ventral midbrain dopaminergic neurons , 2003 .
[10] Gene W. Yeo,et al. Noncoding RNAs in the mammalian central nervous system. , 2006, Annual review of neuroscience.
[11] A. Björklund,et al. Parkinson-Like Neurodegeneration Induced by Targeted Overexpression of α-Synuclein in the Nigrostriatal System , 2002, The Journal of Neuroscience.
[12] R. McKay,et al. A Specific Survival Response in Dopamine Neurons at Most Risk in Parkinson's Disease , 2006, The Journal of Neuroscience.
[13] A Dürr,et al. Causal relation between alpha-synuclein gene duplication and familial Parkinson's disease. , 2004, Lancet.
[14] Mariza de Andrade,et al. High-resolution whole-genome association study of Parkinson disease. , 2005, American journal of human genetics.
[15] C. Svendsen,et al. Over-expression of alpha-synuclein in human neural progenitors leads to specific changes in fate and differentiation. , 2007, Human molecular genetics.
[16] C. V. van Duijn,et al. Parkinson's disease: piecing together a genetic jigsaw. , 2003, Brain : a journal of neurology.
[17] L. Stefanis,et al. Regulation of alpha-synuclein by bFGF in cultured ventral midbrain dopaminergic neurons. , 2003, Journal of neurochemistry.
[18] T. Chase,et al. Muscarinic Receptor Stimulation Induces Translocation of an α-Synuclein Oligomer from Plasma Membrane to a Light Vesicle Fraction in Cytoplasm* , 2001, The Journal of Biological Chemistry.
[19] M. Farrer. Genetics of Parkinson disease: paradigm shifts and future prospects , 2006, Nature Reviews Genetics.
[20] Janel O. Johnson,et al. α-Synuclein Locus Triplication Causes Parkinson's Disease , 2003, Science.
[21] Philippe Amouyel,et al. α-synuclein locus duplication as a cause of familial Parkinson's disease , 2004, The Lancet.
[22] A. Singleton,et al. Lack of evidence for a genetic association between FGF20 and Parkinson's disease in Finnish and Greek patients , 2005, BMC neurology.
[23] E. Martin,et al. A test for linkage and association in general pedigrees: the pedigree disequilibrium test. , 2000, American journal of human genetics.
[24] A. Akaike,et al. FGF-20, a novel neurotrophic factor, preferentially expressed in the substantia nigra pars compacta of rat brain. , 2000, Biochemical and biophysical research communications.
[25] K. Kosik. The neuronal microRNA system , 2006, Nature Reviews Neuroscience.
[26] Eden R Martin,et al. Accounting for linkage in family-based tests of association with missing parental genotypes. , 2003, American journal of human genetics.
[27] M G Spillantini,et al. Alpha-synuclein in Lewy bodies. , 1997, Nature.
[28] Nobuyuki Itoh,et al. Preferential neurotrophic activity of fibroblast growth factor‐20 for dopaminergic neurons through fibroblast growth factor receptor‐1c , 2003, Journal of neuroscience research.
[29] John G Doench,et al. Specificity of microRNA target selection in translational repression. , 2004, Genes & development.
[30] N. Itoh,et al. Evolution of the Fgf and Fgfr gene families. , 2004, Trends in genetics : TIG.
[31] Florian Caiment,et al. A mutation creating a potential illegitimate microRNA target site in the myostatin gene affects muscularity in sheep , 2006, Nature Genetics.
[32] J. Schaack,et al. Overexpression of human α-synuclein causes dopamine neuron death in primary human mesencephalic culture , 2002, Brain Research.
[33] A Dürr,et al. Causal relation between α-synuclein locus duplication as a cause of familial Parkinson's disease , 2004, The Lancet.
[34] S E Ide,et al. Mutation in the alpha-synuclein gene identified in families with Parkinson's disease. , 1997, Science.
[35] J. Haines,et al. Complete genomic screen in Parkinson disease: evidence for multiple genes. , 2001, JAMA.
[36] Florian Caiment,et al. RNAi-Mediated Allelic trans-Interaction at the Imprinted Rtl1/Peg11 Locus , 2005, Current Biology.