Home environment of 11-year-old children born to parents with schizophrenia or bipolar disorder – a controlled, 4-year follow-up study: The Danish High Risk and Resilience Study – VIA 11

Abstract Background The home environment has a major impact on child development. Parental severe mental illness can pose a challenge to the home environment of a child. We aimed to examine the home environment of children of parents with schizophrenia or bipolar disorder and controls longitudinally through at-home assessments. Methods Assessments were conducted within The Danish High Risk and Resilience Study, a nationwide multi-center cohort study of children of parents with schizophrenia or bipolar disorder and population-based controls. The level of at-home stimulation and support was measured at age 7 (N = 508 children) and age 11 (N = 430 children) with the semi-structured HOME Inventory. Results from the 11-year follow-up study were analyzed and compared with 7-year baseline results to examine change across groups. Results At age 11, children of parents with schizophrenia and bipolar disorder had lower levels of stimulation and support than controls (mean (s.d.) = 46.16 (5.56), 46.87 (5.34) and 49.25 (4.37) respectively, p < 0.001). A higher proportion of children with parental schizophrenia or bipolar disorder lived in inadequate home environments at age 11, compared with controls (N (%) = 24 (15.0), 12 (12.2) and 6 (3.5) respectively, p < 0.003). The changes in home environment scores did not differ across groups from age 7 to age 11. Conclusions Assessed longitudinally from the children's age of 7 to 11, children of parents with schizophrenia or bipolar disorder had lower levels of stimulation and support in their homes than controls. Integrated support which can target practical, economic, social and health issues to improve the home environment is indicated.

[1]  T. Werge,et al.  Is the association between parents’ mental illness and child psychopathology mediated via home environment and caregiver’s psychosocial functioning? A mediation analysis of the Danish High Risk and Resilience Study – VIA 7, a population-based cohort study , 2021, Schizophrenia Bulletin Open.

[2]  O. Mors,et al.  A Nationwide Cohort Study of Nonrandom Mating in Schizophrenia and Bipolar Disorder. , 2021, Schizophrenia bulletin.

[3]  A. Danese,et al.  Adversity in childhood is linked to mental and physical health throughout life , 2020, BMJ.

[4]  K. Kendler,et al.  The Rearing Environment and Risk for Major Depression: A Swedish National High-Risk Home-Reared and Adopted-Away Co-Sibling Control Study. , 2020, The American journal of psychiatry.

[5]  K. Kendler,et al.  The rearing environment and the risk for alcohol use disorder: a Swedish national high-risk home-reared v. adopted co-sibling control study , 2020, Psychological Medicine.

[6]  S. Pirkola,et al.  Mental disorders and long‐term labour market outcomes: nationwide cohort study of 2 055 720 individuals , 2019, Acta psychiatrica Scandinavica.

[7]  O. Mors,et al.  Home visits in the Danish High Risk and Resilience Study – VIA 7: assessment of the home environment of 508 7‐year‐old children born to parents diagnosed with schizophrenia or bipolar disorder , 2019, Acta psychiatrica Scandinavica.

[8]  Paul A. Harris,et al.  The REDCap consortium: Building an international community of software platform partners , 2019, J. Biomed. Informatics.

[9]  Sarah M. Tashjian,et al.  Physical home environment is associated with prefrontal cortical thickness in adolescents. , 2019, Developmental science.

[10]  V. Bliksted,et al.  Getting reliable information about the home environment in at-risk families: A systematic literature review , 2019, Social Work in Mental Health.

[11]  D. Axelson,et al.  A Longitudinal Study of Family Functioning in Offspring of Bipolar Parents. , 2018, Journal of the American Academy of Child and Adolescent Psychiatry.

[12]  Sarah K. G. Jensen,et al.  Biological embedding of childhood adversity: from physiological mechanisms to clinical implications , 2017, BMC Medicine.

[13]  M. Maziade.  At Risk for Serious Mental Illness - Screening Children of Patients with Mood Disorders or Schizophrenia. , 2017, The New England journal of medicine.

[14]  K. Kendler,et al.  Criminal offending and the family environment: Swedish national high-risk home-reared and adopted-away co-sibling control study. , 2016, The British journal of psychiatry : the journal of mental science.

[15]  M. Maziade,et al.  Liability indicators aggregate many years before transition to illness in offspring descending from kindreds affected by schizophrenia or bipolar disorder , 2016, Schizophrenia Research.

[16]  K. Kendler,et al.  The rearing environment and risk for drug abuse: a Swedish national high-risk adopted and not adopted co-sibling control study , 2016, Psychological Medicine.

[17]  O. Mors,et al.  The Danish High Risk and Resilience Study – VIA 7 - a cohort study of 520 7-year-old children born of parents diagnosed with either schizophrenia, bipolar disorder or neither of these two mental disorders , 2015, BMC Psychiatry.

[18]  L. Selemon,et al.  Schizophrenia: a tale of two critical periods for prefrontal cortical development , 2015, Translational Psychiatry.

[19]  Dongping Li,et al.  Cumulative risk and child development. , 2013, Psychological bulletin.

[20]  Maria Olejaz,et al.  Denmark health system review. , 2012, Health systems in transition.

[21]  N. Fox,et al.  Adverse Rearing Environments and Neural Development in Children: The Development of Frontal Electroencephalogram Asymmetry , 2011, Biological Psychiatry.

[22]  O. Mors,et al.  The Danish Psychiatric Central Research Register , 2011, Scandinavian journal of public health.

[23]  I. Brockington,et al.  WPA guidance on the protection and promotion of mental health in children of persons with severe mental disorders , 2011, World psychiatry : official journal of the World Psychiatric Association.

[24]  R. Bentall,et al.  Parental communication style and family relationships in children of bipolar parents. , 2008, The British journal of clinical psychology.

[25]  J. Ayuso-Mateos,et al.  Functional Impairment in Patients with Remitted Bipolar Disorder , 2008, Psychotherapy and Psychosomatics.

[26]  T. van Achterberg,et al.  Family Caregiving in Bipolar Disorder: Caregiver Consequences, Caregiver Coping Styles, and Caregiver Distress , 2008, The International journal of social psychiatry.

[27]  K. Abel,et al.  The transmission of risk to children from mothers with schizophrenia: a developmental psychopathology model. , 2008, Clinical psychology review.

[28]  L. Wynne,et al.  I. Genotype-environment interaction in the schizophrenia spectrum: genetic liability and global family ratings in the Finnish Adoption Study. , 2006, Family process.

[29]  C. Puckering,et al.  At HOME in Scotland: validation of the home observation for measurement of the environment inventory. , 2005, Child: care, health and development.

[30]  P. Reder,et al.  Children’s experience of major psychiatric disorder in their parent: An overview , 2005 .

[31]  C. G. Hudson,et al.  Socioeconomic status and mental illness: tests of the social causation and selection hypotheses. , 2005, The American journal of orthopsychiatry.

[32]  M. Östman,et al.  Children in families with a severely mentally ill member , 2002, Social Psychiatry and Psychiatric Epidemiology.

[33]  Shelley E. Taylor,et al.  Risky families: family social environments and the mental and physical health of offspring. , 2002, Psychological bulletin.

[34]  S. Mednick,et al.  A multivariate prediction model of schizophrenia. , 2002, Schizophrenia bulletin.

[35]  D. Clarke,et al.  Perspectives of women living with schizophrenia. , 2000, Psychiatric services.

[36]  D. Kendrick,et al.  Does home visiting improve parenting and the quality of the home environment? A systematic review and meta analysis , 2000, Archives of disease in childhood.

[37]  R. Bradley,et al.  Measuring the Home Environments of Children in Early Adolescence , 2000 .

[38]  L. Appleby,et al.  Mother–infant interaction in post-partum women with schizophrenia and affective disorders , 1999, Psychological Medicine.

[39]  P. Andersen,et al.  Effects of family history and place and season of birth on the risk of schizophrenia. , 1999, The New England journal of medicine.

[40]  V. Mcloyd,et al.  Socioeconomic disadvantage and child development. , 1998, The American psychologist.

[41]  N. Ryan,et al.  Schedule for Affective Disorders and Schizophrenia for School-Age Children-Present and Lifetime Version (K-SADS-PL): initial reliability and validity data. , 1997, Journal of the American Academy of Child and Adolescent Psychiatry.

[42]  D. Cicchetti.  Guidelines, Criteria, and Rules of Thumb for Evaluating Normed and Standardized Assessment Instruments in Psychology. , 1994 .

[43]  M. Radke-yarrow,et al.  Evaluative communications between affectively Ill and well mothers and their children , 1992, Journal of abnormal child psychology.

[44]  S. Goodman,et al.  Schizophrenic and Depressed Mothers: Relational Deficits in Parenting. , 1990 .

[45]  C. Edelbrock,et al.  Manual for the Child: Behavior Checklist and Revised Child Behavior Profile , 1983 .

[46]  R. Bradley,et al.  The Home Observation for Measurement of the Environment (HOME) Scale: A review of research. , 1981 .