Lung Cancer Testing : The Past CXR / sputum screening

At the time of presentation, only 16% of p,atients are diagnosed with a disease stage that has potential for cure by surgical resection. The overall 5-year survivorship for all patients is 15%, despite therapy. However, the 5-year survival for those with pathologic stage I non–small-cell lung cancer (NSCLC) is 58% to 73% after surgery.[2] This significant difference in survivorship makes the identification of early-stage disease desirable. Until recently, however, there had not been a screening test that demonstrated a mortality reduction in lung cancer. In this review, we discuss past attempts at lung cancer screening, the results of the National Lung Cancer Screening Trial (NLST), and innovative tests for lung cancer screening currently being evaluated.

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