Obsessions and compulsions in Gilles de la Tourette's syndrome

The incidence of obsessive-compulsive disorder (OCD) in patients with Gilles de la Tourette's syndrome (GTS) was assessed with a specially designed questionnaire. The Inventory was administered to patients with OCD, patients with GTS, and normal controls. Fifty-one percent of the patients with GTS had significantly elevated Inventory scores. The frequent occurrence of OCD in GTS suggests that the two disorders may share common neurobiologic mechanisms.

[1]  A. Mathews,et al.  Tics and Gilles de la Tourette's Syndrome: A Follow-up Study and Critical Review , 1969, British Journal of Psychiatry.

[2]  B. Shaywitz,et al.  Clonidine ameliorates Gilles de la Tourette syndrome. , 1980, Archives of general psychiatry.

[3]  D. Ingvar,et al.  COMPULSORY SHOUTING (BENEDEK'S “KLAZOMANIA”) ASSOCIATED WITH OCULOGYRIC SPASMS IN CHRONIC EPIDEMIC ENCEPHALITIS , 1961, Acta psychiatrica Scandinavica.

[4]  E. Ascher Psychodynamic considerations in Gilles de la Tourette's disease, maladie des tics, with a report of 5 cases and discussion of the literature. , 1948, The American journal of psychiatry.

[5]  L. Nee,et al.  Tourette syndrome: clinical and family studies. , 1982, Advances in neurology.

[6]  E. Caine,et al.  Gilles de la tourette syndrome: Clinical and family study of 50 cases , 1980, Annals of neurology.

[7]  R. L. Jenkins,et al.  Gilles de la Tourette's syndrome in identical twins. , 1983, Archives of neurology.

[8]  R. Eldridge,et al.  Gilles de la Tourette's syndrome , 1977, Neurology.

[9]  R. Peñalver Manganese poisoning. , 1956, Industrial medicine & surgery.

[10]  W. Weiner,et al.  Gilles de la Tourette syndrome after long‐term chlorpromazine therapy , 1978, Neurology.

[11]  D. Comings,et al.  A case of familial exhibitionism in Tourette's syndrome successfully treated with haloperidol. , 1982, The American journal of psychiatry.

[12]  G. S. Golden,et al.  The effect of central nervous system stimulants on tourette syndrome , 1977, Annals of neurology.

[13]  B. Shaywitz,et al.  Chronic, multiple tics of Gilles de la Tourette's disease. CSF acid monoamine metabolites after probenecid administration. , 1978, Archives of general psychiatry.

[14]  J. Morphew,et al.  Gilles de la Tourette's syndrome: a clinical and psychopathological study. , 1969, The British journal of medical psychology.

[15]  H. Stevens THE SYNDROME OF GILLES DE LA TOURETTE AND ITS TREATMENT: REPORT OF A CASE. , 1964, The Medical annals of the District of Columbia.

[16]  L. Kanner,et al.  A clinical study of Gilles de la Tourette's disease (maladie des tics) in children. , 1959, The American journal of psychiatry.

[17]  M. Trimble,et al.  A clinical study of Gilles de la Tourette syndrome in the United Kingdom. , 1984, Journal of neurology, neurosurgery, and psychiatry.

[18]  Bengt-Arne Eriksson,et al.  Gilles De La Tourette's Syndrome , 1969, British Journal of Psychiatry.

[19]  C. V. Ford,et al.  An objective evaluation of haloperidol in Gilles de la Tourette's syndrome. , 1969, Diseases of the nervous system.

[20]  R P MICHAEL,et al.  Treatment of a Case of Compulsive Swearing , 1957, British medical journal.

[21]  D. Fairweather Psychiatric aspects of the post-encephalitic syndrome. , 1947, The Journal of mental science.

[22]  J. Nathanson,et al.  Central biogenic amine metabolism in children with the syndrome of chronic multiple tics of Gilles de la Tourette: norepinephrine, serotonin, and dopamine. , 1979, Journal of the American Academy of Child Psychiatry.

[23]  J C Rothwell,et al.  Simple tics in Gilles de la Tourette's syndrome are not prefaced by a normal premovement EEG potential. , 1981, Journal of neurology, neurosurgery, and psychiatry.

[24]  M. Aminoff,et al.  Tourette-like Syndrome after Long-term Neuroleptic Drug Treatment , 1982, British Journal of Psychiatry.

[25]  J. Coyle,et al.  Dopaminergic dysfunction in tourette syndrome , 1982 .

[26]  R. Bruun Gilles de la Tourette's syndrome. An overview of clinical experience. , 1984, Journal of the American Academy of Child Psychiatry.

[27]  H C Merchant,et al.  Chronic manganese poisoning. , 1967, Journal of postgraduate medicine.

[28]  C. Darwin,et al.  The Expression of the Emotions in Man and Animals , 1872 .

[29]  A. Shapiro,et al.  Treatment of Gilles de la Tourette syndrome with pimozide. , 1983, The American journal of psychiatry.

[30]  R. Caprioli,et al.  Biogenic amine metabolism in tourette syndrome , 1979, Annals of neurology.

[31]  B. Shaywitz,et al.  Stimulant medications precipitate Tourette's syndrome. , 1982, JAMA.

[32]  P. Clayton,et al.  Psychiatric illness in Tourette syndrome patients and first-degree relatives. , 1982, Advances in neurology.