论文信息 - Sustained release of sulphamethizole from agar beads

Sustained release of sulphamethizole from agar beads

preferentially from an interference with lipoxygenase enzymes. PMNs may aggregate in response to AA as a result of production of biologically active products of lipoxygenase enzymes (Goetzl & Sun 1979), such as hydroperoxy or epoxidc intermediates, or hydroxy fatty acids, e.g. 5-hydroxyeicosatetraenoic acid. These metabolites may play important roles in the biological effects resulting from the metabolism of AA by mammalian cells. The enhancement of the aggregatory REFERENCES

[1] S. Curry,et al. Studies of delayed‐action medication V. Plasma levels and urinary excretion of four different dosage forms of chlorpromazine , 1970, Clinical pharmacology and therapeutics.

[2] N. Lordi,et al. Drug release from compressed hydrophilic matrices. , 1968, Journal of pharmaceutical sciences.

[3] Richard O. Roblin,et al. Studies in Chemotherapy. VII. A Theory of the Relation of Structure to Activity of Sulfanilamide Type Compounds1 , 1942 .

[4] S. Hjertén. THE PREPARATION OF AGAROSE SPHERES FOR CHROMATOGRAPHY OF MOLECULES AND PARTICLES. , 1964, Biochimica et biophysica acta.

[5] L. Philipson,et al. CHROMATOGRAPHY OF ANIMAL VIRUSES ON PEARL-CONDENSED AGAR. , 1964, Biochimica et biophysica acta.

[6] G. C. Walker,et al. Influence of shape factors on kinetics of drug release from matrix tablets. I. Theoretical. , 1974, Journal of pharmaceutical sciences.

[7] T. Higuchi. MECHANISM OF SUSTAINED-ACTION MEDICATION. THEORETICAL ANALYSIS OF RATE OF RELEASE OF SOLID DRUGS DISPERSED IN SOLID MATRICES. , 1963, Journal of pharmaceutical sciences.