Adiponectin down-regulates acyl-coenzyme A:cholesterol acyltransferase-1 in cultured human monocyte-derived macrophages.

[1]  S. Horiuchi,et al.  Glibenclamide acts as an inhibitor of acyl-CoA:cholesterol acyltransferase enzyme. , 2000, Biochemical and biophysical research communications.

[2]  Zhi-Jun Duan,et al.  Human Acyl-CoA:Cholesterol Acyltransferase-1 (ACAT-1) Gene Organization and Evidence That the 4.3-Kilobase ACAT-1 mRNA Is Produced from Two Different Chromosomes* , 1999, The Journal of Biological Chemistry.

[3]  T Nakamura,et al.  Novel modulator for endothelial adhesion molecules: adipocyte-derived plasma protein adiponectin. , 1999, Circulation.

[4]  R. Deckelbaum,et al.  Differential modulation of ACAT1 and ACAT2 transcription and activity by long chain free fatty acids in cultured cells. , 2001, Biochemistry.

[5]  A. Mcfarlane,et al.  Efficient Trace-labelling of Proteins with Iodine , 1958, Nature.

[6]  Zhi-jun Duan,et al.  Synergistic Transcriptional Activation of HumanAcyl-coenzyme A: Cholesterol Acyltransterase-1 Gene by Interferon-γ and All-trans-Retinoic Acid THP-1 Cells* , 2001, The Journal of Biological Chemistry.

[7]  S. Horiuchi,et al.  Expression of ACAT-1 protein in human atherosclerotic lesions and cultured human monocytes-macrophages. , 1998, Arteriosclerosis, thrombosis, and vascular biology.

[8]  S. Kihara,et al.  Adipocyte-Derived Plasma Protein, Adiponectin, Suppresses Lipid Accumulation and Class A Scavenger Receptor Expression in Human Monocyte-Derived Macrophages , 2001, Circulation.

[9]  S. Kihara,et al.  Adipocyte-Derived Plasma Protein Adiponectin Acts as a Platelet-Derived Growth Factor-BB–Binding Protein and Regulates Growth Factor–Induced Common Postreceptor Signal in Vascular Smooth Muscle Cell , 2002, Circulation.

[10]  K. Cadigan,et al.  Molecular cloning and functional expression of human acyl-coenzyme A:cholesterol acyltransferase cDNA in mutant Chinese hamster ovary cells. , 1993, The Journal of biological chemistry.

[11]  S. Horiuchi,et al.  Induction of acyl-coenzyme A:cholesterol acyltransferase-1 by 1,25-dihydroxyvitamin D(3) or 9-cis-retinoic acid in undifferentiated THP-1 cells. , 2001, Journal of lipid research.

[12]  T Nakamura,et al.  Plasma concentrations of a novel, adipose-specific protein, adiponectin, in type 2 diabetic patients. , 2000, Arteriosclerosis, thrombosis, and vascular biology.

[13]  S. Kihara,et al.  Adiponectin, a new member of the family of soluble defense collagens, negatively regulates the growth of myelomonocytic progenitors and the functions of macrophages. , 2000, Blood.

[14]  T. Funahashi,et al.  cDNA cloning and expression of a novel adipose specific collagen-like factor, apM1 (AdiPose Most abundant Gene transcript 1). , 1996, Biochemical and biophysical research communications.

[15]  Y. Morino,et al.  Chemical cross-linking alters high-density lipoprotein to be recognized by a scavenger receptor in rat peritoneal macrophages. , 1991, Biochimica et biophysica acta.

[16]  S. Yamashita,et al.  Enhanced expression of PAI–1 in visceral fat: Possible contributor to vascular disease in obeisty , 1996, Nature Medicine.

[17]  T Nakamura,et al.  Contribution of visceral fat accumulation to the development of coronary artery disease in non-obese men. , 1994, Atherosclerosis.

[18]  T. Chang,et al.  Acyl-coenzyme A:cholesterol acyltransferase. , 1997, Annual review of biochemistry.

[19]  S. Horiuchi,et al.  Acetylated low density lipoprotein reduces its ligand activity for the scavenger receptor after interaction with reconstituted high density lipoprotein. , 1994, The Journal of biological chemistry.

[20]  S. Kihara,et al.  Adiponectin, metabolic risk factors, and cardiovascular events among patients with end-stage renal disease. , 2002, Journal of the American Society of Nephrology : JASN.

[21]  Matthew A. Thomas,et al.  Regulation and Immunolocalization of Acyl-Coenzyme A:Cholesterol Acyltransferase in Mammalian Cells as Studied with Specific Antibodies (*) , 1995, The Journal of Biological Chemistry.

[22]  M. Brown,et al.  Receptor-mediated endocytosis of low-density lipoprotein in cultured cells. , 1983, Methods in enzymology.

[23]  R. Connor,et al.  Evaluation of the antibody-dependent cytotoxic capabilities of individual human monocytes. Role of Fc gamma RI and Fc gamma RII and the effects of cytokines at the single cell level. , 1990, Journal of immunology.

[24]  H. Wang,et al.  Gene expression of acyl-coenzyme-A:cholesterol-acyltransferase is upregulated in human monocytes during differentiation and foam cell formation. , 1996, Arteriosclerosis, thrombosis, and vascular biology.

[25]  S. Kihara,et al.  Adiponectin, an Adipocyte-Derived Plasma Protein, Inhibits Endothelial NF-&kgr;B Signaling Through a cAMP-Dependent Pathway , 2000, Circulation.

[26]  N. Abumrad,et al.  Dexamethasone enhances accumulation of cholesteryl esters by human macrophages. , 1995, The American journal of physiology.

[27]  T Nakamura,et al.  Paradoxical decrease of an adipose-specific protein, adiponectin, in obesity. , 1999, Biochemical and biophysical research communications.

[28]  B. Spiegelman,et al.  Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance. , 1993, Science.

[29]  S. Kihara,et al.  Adiponectin Reduces Atherosclerosis in Apolipoprotein E-Deficient Mice , 2002, Circulation.

[30]  M. Jensen,et al.  Obesity and cardiovascular disease: is body structure a factor? , 1997, Current opinion in lipidology.

[31]  J. Billheimer,et al.  Characterization of Two Human Genes Encoding Acyl Coenzyme A:Cholesterol Acyltransferase-related Enzymes* , 1998, The Journal of Biological Chemistry.

[32]  T Nakamura,et al.  An Adipocyte-Derived Plasma Protein, Adiponectin, Adheres to Injured Vascular Walls , 2000, Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme.

[33]  S. Kihara,et al.  Adiponectin and Metabolic Syndrome , 2004, Arteriosclerosis, thrombosis, and vascular biology.

[34]  S. Kihara,et al.  Obesity, adiponectin and vascular inflammatory disease , 2003, Current opinion in lipidology.

[35]  S. Kihara,et al.  Adiponectin-induced antiangiogenesis and antitumor activity involve caspase-mediated endothelial cell apoptosis. , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[36]  Catherine C. Y. Chang,et al.  Recombinant Acyl-CoA:cholesterol Acyltransferase-1 (ACAT-1) Purified to Essential Homogeneity Utilizes Cholesterol in Mixed Micelles or in Vesicles in a Highly Cooperative Manner* , 1998, The Journal of Biological Chemistry.

[37]  J. Halaas,et al.  Leptin and the regulation of body weight in mammals , 1998, Nature.

[38]  Y. Matsuzawa,et al.  Visceral fat accumulation and cardiovascular disease. , 1995, Obesity research.