STUDIES IN MITRAL STENOSIS: I. A Correlation of Physiologic and Clinical Findings

MITRAL stenosis is unique in that it is the only type of heart disease in which there is a mechanical barrier to the entrance of blood into the left side of the heart. This results in a tendency to congestion and elevation of pressure throughout the pulmonary circulation. Unlike the dynamic situation in left ventricular failure, this stenotic dam may remain static for a long period, with little change in the clinical state of the patient. Ultimately, however, secondary effects on the left auricle, the pulmonary circulation, or the right ventricle develop to such a degree as to determine the final outcome. This condition lends itself, therefore, to the theoretical possibility of relief by reconstructive surgical measures at the site of obstruction, the mitral valve. In recent years this theoretical possibility has been increasingly translated into the realm of the practical with the development of operative procedures which are giving

[1]  S. Robbins,et al.  STUDIES IN MITRAL STENOSIS: II. A Correlation of Post-Mortem Findings with the Clinical Course of the Disease in One Hundred One Cases , 1951 .

[2]  R. Bing,et al.  Physiologic Studies in Mitral Valvular Disease , 1951, Circulation.

[3]  L. Dexter,et al.  Effect of exercise on circulatory dynamics of normal individuals. , 1951, Journal of applied physiology.

[4]  L. Dexter,et al.  Effects of exercise on circulatory dynamics in mitral stenosis. III. , 1951, American heart journal.

[5]  L. Dexter,et al.  Studies of the circulatory dynamics in mitral stenosis. II. Altered dynamics at rest. , 1951, American heart journal.

[6]  A. Hyman,et al.  Pulmonary hypertension in mitral stenosis. , 1950, Lancet.

[7]  R. P. Glover,et al.  Surgery of stenotic valvular disease of the heart. , 1950, Journal of the American Medical Association.

[8]  H. S. Wells,et al.  Pulmonary Hypertension in Heart Disease , 1950 .

[9]  Edwards Je,et al.  Pathology of intrapulmonary arteries and arterioles in mitral stenosis. , 1949 .

[10]  D E HARKEN,et al.  The surgical treatment of mitral stenosis; valvuloplasty. , 1948 .

[11]  R. A. Bloomfield,et al.  The effects of the cardiac glycosides upon the dynamics of the circulation in congestive heart failure; ouabain. , 1948, The Journal of clinical investigation.

[12]  R. Riley,et al.  Studies of the pulmonary circulation at rest and during exercise in normal individuals and in patients with chronic pulmonary disease. , 1948, The American journal of physiology.

[13]  D. Harken,et al.  Mitral Stenosis, Clinico-Physiologic Correlations, with Particular Reference to Surgical Intervention. , 1948, Transactions of the American Clinical and Climatological Association.

[14]  J. Hickam,et al.  EFFECT OF EXERCISE ON CARDIAC OUTPUT AND PULMONARY ARTERIAL PRESSURE IN NORMAL PERSONS AND IN PATIENTS WITH CARDIOVASCULAR DISEASE AND PULMONARY EMPHYSEMA. , 1948, The Journal of clinical investigation.

[15]  R. A. Bloomfield,et al.  RECORDING OF RIGHT HEART PRESSURES IN NORMAL SUBJECTS AND IN PATIENTS WITH CHRONIC PULMONARY DISEASE AND VARIOUS TYPES OF CARDIO-CIRCULATORY DISEASE. , 1946, The Journal of clinical investigation.

[16]  A. M. Jones,et al.  ACUTE LEFT AURICULAR FAILURE , 1944, British heart journal.

[17]  F. Parker,et al.  The Nature and Significance of the Structural Changes in the Lungs in Mitral Stenosis. , 1936, The American journal of pathology.

[18]  D. B. Dill,et al.  Studies in muscular activity , 1928 .