B Cell Activation Triggered by the Formation of the Small Receptor Cluster: A Computational Study
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[1] S. Pierce,et al. The molecular assembly and organization of signaling active B‐cell receptor oligomers , 2009, Immunological reviews.
[2] G. Bhanot. Results from modeling of B-Cell receptors binding to antigen. , 2004, Progress in biophysics and molecular biology.
[3] S. Gauld,et al. Src-family kinases in B-cell development and signaling , 2004, Oncogene.
[4] Kousuke Kasahara,et al. Nuclear localization of Lyn tyrosine kinase mediated by inhibition of its kinase activity. , 2008, Experimental cell research.
[5] Paul C. Fife,et al. Mathematical Aspects of Reacting and Diffusing Systems , 1979 .
[6] Joseph Hanna,et al. The constant region of the membrane immunoglobulin mediates B cell-receptor clustering and signaling in response to membrane antigens. , 2009, Immunity.
[7] A. Perelson,et al. Immunons revisited: binding of multivalent antigens to B cells. , 1997, Molecular immunology.
[8] A. Perelson,et al. Equilibrium binding of multivalent ligands to cells: effects of cell and receptor density. , 1995, Mathematical biosciences.
[9] Kousuke Kasahara,et al. Differential trafficking of Src, Lyn, Yes and Fyn is specified by the state of palmitoylation in the SH4 domain , 2009, Journal of Cell Science.
[10] C. Abram,et al. Convergence of immunoreceptor and integrin signaling , 2007, Immunological reviews.
[11] K. Tsaneva-Atanasova,et al. A model of calcium waves in pancreatic and parotid acinar cells. , 2003, Biophysical journal.
[12] H. Dintzis,et al. Studies on the immunogenicity and tolerogenicity of T-independent antigens. , 1983, Journal of immunology.
[13] F. Batista,et al. B cells acquire particulate antigen in a macrophage-rich area at the boundary between the follicle and the subcapsular sinus of the lymph node. , 2007, Immunity.
[14] T. Lipniacki,et al. Regulation of kinase activity by diffusion and feedback. , 2009, Journal of theoretical biology.
[15] Dmitry I. Strokotov,et al. Is there a difference between T- and B-lymphocyte morphology? , 2009, Journal of biomedical optics.
[16] Elliot L. Botvinick,et al. Visualizing the mechanical activation of Src , 2005, Nature.
[17] J. Ferrell. Self-perpetuating states in signal transduction: positive feedback, double-negative feedback and bistability. , 2002, Current opinion in cell biology.
[18] C. Pleiman. Distinct p53/56^ and p59^ domains associate with nonphosphorylated and phosphorylated lgα. , 1994 .
[19] D. Odde,et al. Potential for Control of Signaling Pathways via Cell Size and Shape , 2006, Current Biology.
[20] E. Stanley,et al. Autophosphorylation Induces Autoactivation and a Decrease in the Src Homology 2 Domain Accessibility of the Lyn Protein Kinase (*) , 1995, The Journal of Biological Chemistry.
[21] Facundo D Batista,et al. Early events in B cell activation. , 2010, Annual review of immunology.
[22] J. Jongstra,et al. Distinct p53/56lyn and p59fyn domains associate with nonphosphorylated and phosphorylated Ig-alpha. , 1994, Proceedings of the National Academy of Sciences of the United States of America.
[23] Werner Dubitzky,et al. Bistable switching and excitable behaviour in the activation of Src at mitosis , 2006, ISMB.
[24] A. Chakraborty,et al. Positive feedback regulation results in spatial clustering and fast spreading of active signaling molecules on a cell membrane. , 2009, The Journal of chemical physics.
[25] Boris N Kholodenko,et al. Toggle switches, pulses and oscillations are intrinsic properties of the Src activation/deactivation cycle , 2009, The FEBS journal.
[26] Mikael Bodén,et al. A probabilistic model of nuclear import of proteins , 2011, Bioinform..
[27] Wei-Shou Hu,et al. Tweaking biological switches through a better understanding of bistability behavior. , 2008, Current opinion in biotechnology.
[28] Melvin E Andersen,et al. A bistable switch underlying B-cell differentiation and its disruption by the environmental contaminant 2,3,7,8-tetrachlorodibenzo-p-dioxin. , 2010, Toxicological sciences : an official journal of the Society of Toxicology.
[29] Akihiro Kusumi,et al. Single-molecule imaging analysis of Ras activation in living cells. , 2004, Proceedings of the National Academy of Sciences of the United States of America.
[30] Boris N. Kholodenko,et al. Signalling ballet in space and time , 2010, Nature Reviews Molecular Cell Biology.
[31] Z. Zhang,et al. Structure, mechanism, and specificity of protein-tyrosine phosphatases. , 1997, Current topics in cellular regulation.
[32] Werner Dubitzky,et al. Deactivation of Src Family Kinases: Hypothesis Testing Using a Monte Carlo Sensitivity Analysis of Systems-Level Properties , 2007, J. Comput. Biol..
[33] Paul Herzmark,et al. Morphology matters in immune cell chemotaxis: membrane asymmetry affects amplification , 2006, Physical biology.
[34] K. Sada,et al. Role of the Syk autophosphorylation site and SH2 domains in B cell antigen receptor signaling , 1995, The Journal of experimental medicine.
[35] T. Kurosaki,et al. Phospholipase C-γ2 and Vav cooperate within signaling microclusters to propagate B cell spreading in response to membrane-bound antigen , 2008, The Journal of Experimental Medicine.
[36] Mary Louise Turgeon,et al. Clinical Hematology: Theory and Procedures , 1988 .
[37] A. Bruckbauer,et al. The Membrane Skeleton Controls Diffusion Dynamics and Signaling through the B Cell Receptor , 2010, Immunity.
[38] B. Vogelstein,et al. Molecular determinants of immunogenicity: the immunon model of immune response. , 1976, Proceedings of the National Academy of Sciences of the United States of America.
[39] A. Tarakhovsky,et al. Essential role of Src-family protein tyrosine kinases in NF-κB activation during B cell development , 2003, Nature Immunology.
[40] B. Kholodenko. Cell-signalling dynamics in time and space , 2006, Nature Reviews Molecular Cell Biology.
[41] S. Pierce,et al. It's all about change: the antigen-driven initiation of B-cell receptor signaling. , 2010, Cold Spring Harbor perspectives in biology.
[42] Kousuke Kasahara,et al. Trafficking of Lyn through the Golgi caveolin involves the charged residues on αE and αI helices in the kinase domain , 2004, The Journal of cell biology.
[43] R. Geahlen. Syk and pTyr'd: Signaling through the B cell antigen receptor. , 2009, Biochimica et biophysica acta.
[44] James E. Ferrell,et al. Bistability in cell signaling: How to make continuous processes discontinuous, and reversible processes irreversible. , 2001, Chaos.
[45] V. Tybulewicz,et al. CD19 is essential for B cell activation by promoting B cell receptor–antigen microcluster formation in response to membrane-bound ligand , 2008, Nature Immunology.
[46] Roger D. Kamm,et al. Mechanotransduction through growth-factor shedding into the extracellular space , 2004, Nature.
[47] T. Lipniacki,et al. Spatial gradients in kinase cascade regulation. , 2010, IET systems biology.
[48] M. Poenie,et al. Dynamic polarization of the microtubule cytoskeleton during CTL-mediated killing. , 2002, Immunity.
[49] Edward,et al. Specific cellular stimulation in the primary immune response: A quantized model , 2022 .
[50] B N Kholodenko,et al. Spatial gradients of cellular phospho‐proteins , 1999, FEBS letters.
[51] N. Tonks,et al. Purification of the major protein-tyrosine-phosphatases of human placenta. , 1988, The Journal of biological chemistry.
[52] Carsten Schultz,et al. Live-Cell Imaging of Enzyme-Substrate Interaction Reveals Spatial Regulation of PTP1B , 2007, Science.
[53] Thomas Schmidt,et al. Single-molecule diffusion reveals similar mobility for the Lck, H-ras, and K-ras membrane anchors. , 2006, Biophysical journal.
[54] Victor L. J. Tybulewicz,et al. The SYK tyrosine kinase: a crucial player in diverse biological functions , 2010, Nature Reviews Immunology.
[55] Boris N Kholodenko,et al. Long-range signaling by phosphoprotein waves arising from bistability in protein kinase cascades , 2006, Molecular systems biology.
[56] P. R. ten Wolde,et al. Spatio-temporal correlations can drastically change the response of a MAPK pathway , 2009, Proceedings of the National Academy of Sciences.
[57] B. Rongish,et al. Transient nuclear localization of fyn kinase during development in zebrafish , 2000, The Anatomical record.
[58] M. Reth,et al. Amplification of B cell antigen receptor signaling by a Syk/ITAM positive feedback loop. , 2002, Molecular cell.
[59] T. Kurosaki,et al. Phospholipase C-γ2 and Vav cooperate within signaling microclusters to propagate B cell spreading in response to membrane-bound antigen , 2008 .
[60] W. S. Hlavacek,et al. Investigation of Early Events in FcεRI-Mediated Signaling Using a Detailed Mathematical Model1 , 2003, The Journal of Immunology.
[61] Philippos K. Tsourkas,et al. Mechanisms of B-cell synapse formation predicted by Monte Carlo simulation. , 2006, Biophysical journal.
[62] Hannah H. Chang,et al. Multistable and multistep dynamics in neutrophil differentiation , 2006, BMC Cell Biology.
[63] F. Batista,et al. The who, how and where of antigen presentation to B cells , 2009, Nature Reviews Immunology.
[64] J. Monroe,et al. B-cell receptor. , 2008, Advances in experimental medicine and biology.
[65] Douglas A. Lauffenburger,et al. A Model for Mechanotransduction in Cardiac Muscle: Effects of Extracellular Matrix Deformation on Autocrine Signaling , 2004, Annals of Biomedical Engineering.
[66] Jay T. Groves,et al. Synaptic pattern formation during cellular recognition , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[67] I. Bahar,et al. Structure and dynamic regulation of Src-family kinases , 2008, Cellular and Molecular Life Sciences.
[68] J. Goldman,et al. B Cell Ligand Discrimination Through a Spreading and Contraction Response , 2006, Science.
[69] M. Neuberger,et al. B cells acquire antigen from target cells after synapse formation , 2001, Nature.