Reproducibility of glucose, fatty acid and VLDL kinetics and multi-organ insulin sensitivity in obese subjects with non-alcoholic fatty liver disease

[1]  F. Magkos,et al.  Metabolic actions of insulin in men and women. , 2010, Nutrition.

[2]  B. S. Mohammed,et al.  Effect of fenofibrate and niacin on intrahepatic triglyceride content, very low-density lipoprotein kinetics, and insulin action in obese subjects with nonalcoholic fatty liver disease. , 2010, The Journal of clinical endocrinology and metabolism.

[3]  J. Kirwan,et al.  Free fatty acid-induced hepatic insulin resistance is attenuated following lifestyle intervention in obese individuals with impaired glucose tolerance. , 2010, The Journal of clinical endocrinology and metabolism.

[4]  B. S. Mohammed,et al.  Intrahepatic fat, not visceral fat, is linked with metabolic complications of obesity , 2009, Proceedings of the National Academy of Sciences.

[5]  B. S. Mohammed,et al.  Weight Loss Reduces Liver Fat and Improves Hepatic and Skeletal Muscle Insulin Sensitivity in Obese Adolescents , 2009, Obesity.

[6]  D. Reeds,et al.  Dietary fat and carbohydrates differentially alter insulin sensitivity during caloric restriction. , 2009, Gastroenterology.

[7]  F. Magkos,et al.  Stable isotope-labeled tracers for the investigation of fatty acid and triglyceride metabolism in humans in vivo , 2009, Clinical lipidology.

[8]  B. S. Mohammed,et al.  Alterations in Fatty Acid Kinetics in Obese Adolescents With Increased Intrahepatic Triglyceride Content , 2009, Obesity.

[9]  L. Heinemann,et al.  Fluctuation and reproducibility of exposure and effect of insulin glargine in healthy subjects * , 2008, Diabetes, obesity & metabolism.

[10]  B. S. Mohammed,et al.  Liver, muscle, and adipose tissue insulin action is directly related to intrahepatic triglyceride content in obese subjects. , 2008, Gastroenterology.

[11]  M. Lazo,et al.  Brief Communication: Clinical Implications of Short-Term Variability in Liver Function Test Results , 2008, Annals of Internal Medicine.

[12]  B. S. Mohammed,et al.  Alterations in adipose tissue and hepatic lipid kinetics in obese men and women with nonalcoholic fatty liver disease. , 2008, Gastroenterology.

[13]  A. Kotronen,et al.  Rosiglitazone reduces liver fat and insulin requirements and improves hepatic insulin sensitivity and glycemic control in patients with type 2 diabetes requiring high insulin doses. , 2008, The Journal of clinical endocrinology and metabolism.

[14]  P. Schrauwen,et al.  The insulin-sensitizing effect of rosiglitazone in type 2 diabetes mellitus patients does not require improved in vivo muscle mitochondrial function. , 2008, The Journal of clinical endocrinology and metabolism.

[15]  A. Kotronen,et al.  Tissue specificity of insulin resistance in humans: fat in the liver rather than muscle is associated with features of the metabolic syndrome , 2007, Diabetologia.

[16]  F. Magkos,et al.  Reproducibility of stable isotope-labeled tracer measures of VLDL-triglyceride and VLDL-apolipoprotein B-100 kinetics Published, JLR Papers in Press, February 26, 2007. , 2007, Journal of Lipid Research.

[17]  R. Owen,et al.  Insulin-sensitizing effects of thiazolidinediones are not linked to adiponectin receptor expression in human fat or muscle. , 2007, American journal of physiology. Endocrinology and metabolism.

[18]  G. Targher,et al.  Non-alcoholic fatty liver disease and increased risk of cardiovascular disease. , 2007, Atherosclerosis.

[19]  S. Klein,et al.  Assessment of intrahepatic triglyceride content using magnetic resonance spectroscopy. , 2007, Journal of the cardiometabolic syndrome.

[20]  J. Barkin.  Gastric Bypass Surgery Improves Metabolic and Hepatic Abnormalities Associated With Nonalcoholic Fatty Liver Disease , 2007 .

[21]  F. Magkos,et al.  No effect of menstrual cycle phase on basal very-low-density lipoprotein triglyceride and apolipoprotein B-100 kinetics. , 2006, American journal of physiology. Endocrinology and metabolism.

[22]  B. S. Mohammed,et al.  Lipid metabolism response to a single, prolonged bout of endurance exercise in healthy young men. , 2006, American journal of physiology. Endocrinology and metabolism.

[23]  A. Häkkinen,et al.  Overproduction of large VLDL particles is driven by increased liver fat content in man , 2006, Diabetologia.

[24]  O. Cummings,et al.  Design and validation of a histological scoring system for nonalcoholic fatty liver disease , 2005, Hepatology.

[25]  M. Jensen,et al.  Pioglitazone increases non-esterified fatty acid clearance in upper body obesity , 2005, Diabetologia.

[26]  U. Keller,et al.  Effects of atorvastatin versus fenofibrate on apoB-100 and apoA-I kinetics in mixed hyperlipidemia Published, JLR Papers in Press, October 1, 2003. DOI 10.1194/jlr.M300309-JLR200 , 2004, Journal of Lipid Research.

[27]  S. Klein,et al.  Effect of sex and obesity on basal VLDL-triacylglycerol kinetics. , 2003, The American journal of clinical nutrition.

[28]  G. Watts,et al.  Differential regulation of lipoprotein kinetics by atorvastatin and fenofibrate in subjects with the metabolic syndrome. , 2003, Diabetes.

[29]  S. Klein,et al.  Effect of weight loss on VLDL-triglyceride and apoB-100 kinetics in women with abdominal obesity. , 2003, American journal of physiology. Endocrinology and metabolism.

[30]  J. McGill,et al.  Thiazolidinediones enhance insulin-mediated suppression of fatty acid flux in type 2 diabetes mellitus. , 2002, Metabolism: clinical and experimental.

[31]  S. Klein,et al.  Use of stable isotopically labeled tracers to measure very low density lipoprotein-triglyceride turnover. , 2002, Journal of lipid research.

[32]  J. Burnett,et al.  Apolipoprotein B Metabolism: Tracer Kinetics, Models, and Metabolic Studies , 2002, Critical reviews in clinical laboratory sciences.

[33]  M. Quon,et al.  Repeatability characteristics of simple indices of insulin resistance: implications for research applications. , 2001, The Journal of clinical endocrinology and metabolism.

[34]  G. Marchesini,et al.  Nonalcoholic fatty liver disease: a feature of the metabolic syndrome. , 2001, Diabetes.

[35]  Robert Ross,et al.  Reduction in Obesity and Related Comorbid Conditions after Diet-Induced Weight Loss or Exercise-Induced Weight Loss in Men , 2000, Annals of Internal Medicine.

[36]  W G Hopkins,et al.  Measures of Reliability in Sports Medicine and Science , 2000, Sports medicine.

[37]  L. Berglund,et al.  Relationships between muscle morphology and insulin sensitivity are improved after adjustment for intra-individual variability in 70-year-old men. , 2000, Acta physiologica Scandinavica.

[38]  O. Ljungqvist,et al.  The hyperinsulinaemic-euglycaemic glucose clamp: reproducibility and metabolic effects of prolonged insulin infusion in healthy subjects. , 2000, Clinical science.

[39]  B. Fagerberg,et al.  The euglycemic hyperinsulinemic clamp examination: variability and reproducibility. , 2000, Scandinavian journal of clinical and laboratory investigation.

[40]  D. Hachey,et al.  Validation of a new procedure to determine plasma fatty acid concentration and isotopic enrichment. , 1999, Journal of lipid research.

[41]  C Ricós,et al.  Current databases on biological variation: pros, cons and progress. , 1999, Scandinavian journal of clinical and laboratory investigation.

[42]  J. Connell,et al.  THE EUGLYCAEMIC HYPERINSULINAEMIC CLAMP: AN EVALUATION OF CURRENT METHODOLOGY , 1997, Clinical and experimental pharmacology & physiology.

[43]  G. Lewis.  Fatty acid regulation of very low density lipoprotein production. , 1997, Current opinion in lipidology.

[44]  S. Kjeldsen,et al.  Insulin sensitivity relates to other cardiovascular risk factors in young men: validation of some modifications of the hyperinsulinaemic, isoglycaemic glucose clamp technique. , 1997, Blood pressure. Supplement.

[45]  B. Rosner,et al.  Effects of postmenopausal estrogen replacement on the concentrations and metabolism of plasma lipoproteins. , 1991, The New England journal of medicine.

[46]  V. Schumaker,et al.  Plasma very low density lipoproteins contain a single molecule of apolipoprotein B. , 1988, Journal of lipid research.

[47]  F. Schaffner,et al.  Nonalcoholic fatty liver disease. , 1986, Progress in liver diseases.

[48]  N. Le,et al.  Regulation of the production and catabolism of plasma low density lipoproteins in hypertriglyceridemic subjects. Effect of weight loss. , 1985, The Journal of clinical investigation.

[49]  R. DeFronzo,et al.  Glucose clamp technique: a method for quantifying insulin secretion and resistance. , 1979, The American journal of physiology.