The genetics of adiponectin

[1]  C. Dina,et al.  Does the −11377 promoter variant of APM1 gene contribute to the genetic risk for Type 2 diabetes mellitus in Japanese families? , 2003, Diabetologia.

[2]  M. Matsuda,et al.  Role of Adiponectin in Preventing Vascular Stenosis , 2002, The Journal of Biological Chemistry.

[3]  K. Clément,et al.  Single-nucleotide polymorphism haplotypes in the both proximal promoter and exon 3 of the APM1 gene modulate adipocyte-secreted adiponectin hormone levels and contribute to the genetic risk for type 2 diabetes in French Caucasians. , 2002, Human molecular genetics.

[4]  M. Stumvoll,et al.  The Peroxisome Proliferator-Activated Receptor-γ2 Pro12Ala Polymorphism , 2002 .

[5]  Philippe Froguel,et al.  Disruption of Adiponectin Causes Insulin Resistance and Neointimal Formation* , 2002, The Journal of Biological Chemistry.

[6]  Jonathan Krakoff,et al.  Adiponectin and development of type 2 diabetes in the Pima Indian population , 2002, The Lancet.

[7]  M. Matsuda,et al.  Association of adiponectin mutation with type 2 diabetes: a candidate gene for the insulin resistance syndrome. , 2002, Diabetes.

[8]  P. Scherer,et al.  A haplotype at the adiponectin locus is associated with obesity and other features of the insulin resistance syndrome. , 2002, Diabetes.

[9]  S. Kihara,et al.  Adipocyte-Derived Plasma Protein Adiponectin Acts as a Platelet-Derived Growth Factor-BB–Binding Protein and Regulates Growth Factor–Induced Common Postreceptor Signal in Vascular Smooth Muscle Cell , 2002, Circulation.

[10]  M. Matsuda,et al.  Diet-induced insulin resistance in mice lacking adiponectin/ACRP30 , 2002, Nature Medicine.

[11]  S. Maruoka,et al.  Decreased plasma adiponectin concentrations in women with dyslipidemia. , 2002, The Journal of clinical endocrinology and metabolism.

[12]  C. Bogardus,et al.  Plasma adiponectin concentration is associated with skeletal muscle insulin receptor tyrosine phosphorylation, and low plasma concentration precedes a decrease in whole-body insulin sensitivity in humans. , 2002, Diabetes.

[13]  A. Xu,et al.  Hydroxylation and Glycosylation of the Four Conserved Lysine Residues in the Collagenous Domain of Adiponectin , 2002, The Journal of Biological Chemistry.

[14]  Y. Matsuzawa,et al.  Serum adiponectin and leptin levels in patients with lipodystrophies , 2002 .

[15]  C. Dina,et al.  Genome-wide search for type 2 diabetes in Japanese affected sib-pairs confirms susceptibility genes on 3q, 15q, and 20q and identifies two new candidate Loci on 7p and 11p. , 2002, Diabetes.

[16]  A. Krainer,et al.  Listening to silence and understanding nonsense: exonic mutations that affect splicing , 2002, Nature Reviews Genetics.

[17]  N. Fineberg,et al.  Role of amylin in insulin secretion and action in humans: antagonist studies across the spectrum of insulin sensitivity , 2002, Diabetes/metabolism research and reviews.

[18]  Lee-Ming Chuang,et al.  Synthetic peroxisome proliferator-activated receptor-gamma agonist, rosiglitazone, increases plasma levels of adiponectin in type 2 diabetic patients. , 2002, Diabetes care.

[19]  C. Dina,et al.  Genetic variation in the gene encoding adiponectin is associated with an increased risk of type 2 diabetes in the Japanese population. , 2002, Diabetes.

[20]  S. Kenwrick,et al.  Disease-associated mutations in L1 CAM interfere with ligand interactions and cell-surface expression. , 2002, Human molecular genetics.

[21]  M. Stumvoll,et al.  Association of the T-G polymorphism in adiponectin (exon 2) with obesity and insulin sensitivity: interaction with family history of type 2 diabetes. , 2002, Diabetes.

[22]  L. Rossetti,et al.  Endogenous glucose production is inhibited by the adipose-derived protein Acrp30. , 2001, The Journal of clinical investigation.

[23]  C. Dina,et al.  A genome-wide scan for coronary heart disease suggests in Indo-Mauritians a susceptibility locus on chromosome 16p13 and replicates linkage with the metabolic syndrome on 3q27. , 2001, Human molecular genetics.

[24]  B. Spiegelman,et al.  Adipose tissue reduction in mice lacking the translational inhibitor 4E-BP1 , 2001, Nature Medicine.

[25]  J. Blangero,et al.  The genetic basis of plasma variation in adiponectin, a global endophenotype for obesity and the metabolic syndrome. , 2001, The Journal of clinical endocrinology and metabolism.

[26]  E. Lander,et al.  On the allelic spectrum of human disease. , 2001, Trends in genetics : TIG.

[27]  C. Sato,et al.  Identification and Adipocyte Differentiation-dependent Expression of the Unique Disialic Acid Residue in an Adipose Tissue-specific Glycoprotein, Adipo Q* , 2001, The Journal of Biological Chemistry.

[28]  Y. Terauchi,et al.  The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity , 2001, Nature Medicine.

[29]  P. Scherer,et al.  The adipocyte-secreted protein Acrp30 enhances hepatic insulin action , 2001, Nature Medicine.

[30]  J. Pritchard.  Are rare variants responsible for susceptibility to complex diseases? , 2001, American journal of human genetics.

[31]  T. Funahashi,et al.  Circulating concentrations of the adipocyte protein adiponectin are decreased in parallel with reduced insulin sensitivity during the progression to type 2 diabetes in rhesus monkeys. , 2001, Diabetes.

[32]  T. Funahashi,et al.  The Journal of Clinical Endocrinology & Metabolism Printed in U.S.A. Copyright © 2001 by The Endocrine Society Hypoadiponectinemia in Obesity and Type 2 Diabetes: Close Association with Insulin Resistance , 2022 .

[33]  J. Corbett,et al.  Pancreatic β-Cell Damage Mediated by β-Cell Production of Interleukin-1 , 2001, The Journal of Biological Chemistry.

[34]  S. Kihara,et al.  Adipocyte-Derived Plasma Protein, Adiponectin, Suppresses Lipid Accumulation and Class A Scavenger Receptor Expression in Human Monocyte-Derived Macrophages , 2001, Circulation.

[35]  H. Lodish,et al.  Proteolytic cleavage product of 30-kDa adipocyte complement-related protein increases fatty acid oxidation in muscle and causes weight loss in mice. , 2001, Proceedings of the National Academy of Sciences of the United States of America.

[36]  J. Weber,et al.  Quantitative trait loci on chromosomes 3 and 17 influence phenotypes of the metabolic syndrome. , 2000, Proceedings of the National Academy of Sciences of the United States of America.

[37]  C. Dina,et al.  Genomewide search for type 2 diabetes-susceptibility genes in French whites: evidence for a novel susceptibility locus for early-onset diabetes on chromosome 3q27-qter and independent replication of a type 2-diabetes locus on chromosome 1q21-q24. , 2000, American journal of human genetics.

[38]  Tom H. Lindner,et al.  Genetic variation in the gene encoding calpain-10 is associated with type 2 diabetes mellitus , 2000, Nature Genetics.

[39]  S. Kihara,et al.  Adiponectin, a new member of the family of soluble defense collagens, negatively regulates the growth of myelomonocytic progenitors and the functions of macrophages. , 2000, Blood.

[40]  G. Lathrop,et al.  EIF2AK3, encoding translation initiation factor 2-α kinase 3, is mutated in patients with Wolcott-Rallison syndrome , 2000, Nature Genetics.

[41]  S. Kihara,et al.  Genomic structure and mutations in adipose-specific gene, adiponectin , 2000, International Journal of Obesity.

[42]  T Nakamura,et al.  Plasma concentrations of a novel, adipose-specific protein, adiponectin, in type 2 diabetic patients. , 2000, Arteriosclerosis, thrombosis, and vascular biology.

[43]  J. Schaeffer,et al.  Somatostatin Inhibits Insulin and Glucagon Secretion via Two Receptor Subtypes: An in Vitro Study of Pancreatic Islets from Somatostatin Receptor 2 Knockout Mice. , 2000, Endocrinology.

[44]  E. Ravussin,et al.  Decreased Expression Of apM1 in Omental and Subcutaneous Adipose Tissue of Humans With Type 2 Diabetes , 2000, International journal of experimental diabetes research.

[45]  T Nakamura,et al.  Novel modulator for endothelial adhesion molecules: adipocyte-derived plasma protein adiponectin. , 1999, Circulation.

[46]  T Nakamura,et al.  Paradoxical decrease of an adipose-specific protein, adiponectin, in obesity. , 1999, Biochemical and biophysical research communications.

[47]  N. Shimizu,et al.  Organization of the gene for gelatin-binding protein (GBP28). , 1999, Gene.

[48]  T. Langmann,et al.  Identification and characterization of the human adipocyte apM-1 promoter. , 1998, Biochimica et biophysica acta.

[49]  A. Hofman,et al.  RELATION OF ALLELES OF THE COLLAGEN TYPE I a 1 GENE TO BONE DENSITY AND THE RISK OF OSTEOPOROTIC FRACTURES IN POSTMENOPAUSAL WOMEN , 2000 .

[50]  Philipp E. Scherer,et al.  The crystal structure of a complement-1q family protein suggests an evolutionary link to tumor necrosis factor , 1998, Current Biology.

[51]  M. Mcdaniel,et al.  Insulin Mediates Glucose-stimulated Phosphorylation of PHAS-I by Pancreatic Beta Cells , 1998, The Journal of Biological Chemistry.

[52]  S. Kimball,et al.  Modulation of translation initiation in rat skeletal muscle and liver in response to food intake. , 1997, Biochemical and biophysical research communications.

[53]  Klaus Resch,et al.  The Interleukin-1 Receptor Accessory Protein (IL-1RAcP) Is Essential for IL-1-induced Activation of Interleukin-1 Receptor-associated Kinase (IRAK) and Stress-activated Protein Kinases (SAP Kinases)* , 1997, The Journal of Biological Chemistry.

[54]  E. Lander,et al.  Characterization of the MODY3 phenotype. Early-onset diabetes caused by an insulin secretion defect. , 1997, The Journal of clinical investigation.

[55]  Y. Nakano,et al.  Isolation and characterization of GBP28, a novel gelatin-binding protein purified from human plasma. , 1996, Journal of biochemistry.

[56]  B. Spiegelman,et al.  AdipoQ Is a Novel Adipose-specific Gene Dysregulated in Obesity (*) , 1996, The Journal of Biological Chemistry.

[57]  T. Funahashi,et al.  cDNA cloning and expression of a novel adipose specific collagen-like factor, apM1 (AdiPose Most abundant Gene transcript 1). , 1996, Biochemical and biophysical research communications.

[58]  Philipp E. Scherer,et al.  A Novel Serum Protein Similar to C1q, Produced Exclusively in Adipocytes (*) , 1995, The Journal of Biological Chemistry.

[59]  P. Edwards,et al.  Atherosclerosis: basic mechanisms. Oxidation, inflammation, and genetics. , 1995, Circulation.

[60]  A. Baldini,et al.  Three members of the human cystatin gene superfamily, AHSG, HRG, and KNG, map within one megabase of genomic DNA at 3q27. , 1995, Cytogenetics and cell genetics.

[61]  G. Hitman,et al.  Apolipoprotein-D polymorphism: a genetic marker for obesity and hyperinsulinemia. , 1994, The Journal of clinical endocrinology and metabolism.

[62]  I. Pastan,et al.  Cooperative function of two separate enhancers of the human epidermal growth factor receptor proto-oncogene. , 1989, The Journal of biological chemistry.