Isoxazoline containing natural products as anticancer agents: a review.

[1]  Xiaoli Zhang,et al.  Discovery of Anticancer Agents of Diverse Natural Origin. , 2016, Anticancer research.

[2]  Anil Kumar Sharma,et al.  Pyrazole containing natural products: synthetic preview and biological significance. , 2013, European journal of medicinal chemistry.

[3]  K. Petit,et al.  Marine natural products and related compounds as anticancer agents: an overview of their clinical status. , 2013, Anti-cancer agents in medicinal chemistry.

[4]  A. M. Vijesh,et al.  New pyrazole derivatives containing 1,2,4-triazoles and benzoxazoles as potent antimicrobial and analgesic agents. , 2013, European journal of medicinal chemistry.

[5]  Xiao-Jing Shi,et al.  Design and synthesis of novel 1,2,3-triazole-dithiocarbamate hybrids as potential anticancer agents. , 2013, European journal of medicinal chemistry.

[6]  Lanying Liu,et al.  Design, synthesis and biological evaluation of novel hybrid compounds of imidazole scaffold-based 2-benzylbenzofuran as potent anticancer agents. , 2013, European journal of medicinal chemistry.

[7]  R. Quinn,et al.  Bromotyrosine alkaloids from the Australian marine sponge Pseudoceratina verrucosa. , 2013, Journal of natural products.

[8]  J. A. Paixão,et al.  Chiral 6,7-bis(hydroxymethyl)-1H,3H-pyrrolo[1,2-c]thiazoles with anti-breast cancer properties. , 2013, European journal of medicinal chemistry.

[9]  M. Garson,et al.  Psammaplysin derivatives from the Balinese marine sponge Aplysinella strongylata. , 2012, Journal of natural products.

[10]  D. Youssef,et al.  Subereamolline A as a Potent Breast Cancer Migration, Invasion and Proliferation Inhibitor and Bioactive Dibrominated Alkaloids from the Red Sea Sponge Pseudoceratina arabica , 2012, Marine drugs.

[11]  A. Suárez,et al.  Cytotoxic effects of Fisturalin-3 and 11-Deoxyfisturalin-3 on Jurkat and U937 cell lines. , 2012, Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia.

[12]  Basappa,et al.  Anti-cancer activity of novel dibenzo[b,f]azepine tethered isoxazoline derivatives , 2012, BMC chemical biology.

[13]  Rui Hu,et al.  Anthranilic acid-based diamides derivatives incorporating aryl-isoxazoline pharmacophore as potential anticancer agents: design, synthesis and biological evaluation. , 2012, European journal of medicinal chemistry.

[14]  M. López-Lázaro,et al.  Pro-oxidant natural products as anticancer agents. , 2012, Current drug targets.

[15]  Joanne I. Yeh,et al.  HIV-1 Nef interaction influences the ATP-binding site of the Src-family kinase, Hck , 2012, BMC chemical biology.

[16]  A. Carroll,et al.  Twilight zone sponges from Guam yield theonellin isocyanate and psammaplysins I and J. , 2012, Journal of natural products.

[17]  A. Kamal.  Synthesis and Biological Evaluation of 3,5-Diaryl Isoxazoline/Isoxazole Linked 2, 3-Dihydroquinazolinone Hybrids as Anticancer Agents. , 2011 .

[18]  Y. Jeong,et al.  Synthesis, spectral, crystal structure and in vitro antimicrobial evaluation of imidazole/benzotriazole substituted piperidin-4-one derivatives. , 2011, European journal of medicinal chemistry.

[19]  Thokhir Basha Shaik,et al.  Synthesis and biological evaluation of 3,5-diaryl isoxazoline/isoxazole linked 2,3-dihydroquinazolinone hybrids as anticancer agents. , 2011, European journal of medicinal chemistry.

[20]  J. Brenton,et al.  Total syntheses of subereamollines A and B. , 2011, Organic & biomolecular chemistry.

[21]  C. Fokunang,et al.  Synthesis of some p-toluenesulfonyl-hydrazinothiazoles and hydrazino-bis-thiazoles and their anticancer activity. , 2010, European journal of medicinal chemistry.

[22]  S. Sen,et al.  Design, synthesis and biological evaluation of 3,5-diaryl-isoxazoline/isoxazole-pyrrolobenzodiazepine conjugates as potential anticancer agents. , 2010, European journal of medicinal chemistry.

[23]  Takuma Sasaki,et al.  Purealidins B and C, New Bromotyrosine Alkaloids from the Okinawan Marine Sponge Psammaplysilla purea. , 2010 .

[24]  A. Kinghorn,et al.  Discovery of anticancer agents of diverse natural origin , 2009, Pure and applied chemistry. Chimie pure et appliquee.

[25]  A. Carroll,et al.  Clavatadines C-E, guanidine alkaloids from the Australian sponge Suberea clavata. , 2009, Journal of natural products.

[26]  J. Kalaitzis,et al.  Ianthesine E, a new bromotyrosine-derived metabolite from the Great Barrier Reef sponge Pseudoceratina sp. , 2008, Natural product research.

[27]  D. Youssef,et al.  Bioactive brominated metabolites from the red sea sponge Suberea mollis. , 2008, Journal of natural products.

[28]  L. A. Shaala,et al.  Bioactive brominated metabolites from the Red Sea sponge Pseudoceratina arabica. , 2008, Journal of natural products.

[29]  J. Carballo,et al.  Cytotoxic dibromotyrosine-derived metabolites from the sponge Aplysina gerardogreeni. , 2007, Bioorganic & medicinal chemistry.

[30]  Guangmin Yao,et al.  Bioactive constituents from the marine crinoid Himerometra magnipinna. , 2007, Journal of natural products.

[31]  Karl-Heinz Altmann,et al.  Anticancer drugs from nature--natural products as a unique source of new microtubule-stabilizing agents. , 2007, Natural product reports.

[32]  D. Newman,et al.  Natural products as sources of new drugs over the last 25 years. , 2007, Journal of natural products.

[33]  R. Obata,et al.  Asymmetric Synthesis of Aerothionin, a Marine Dimeric Spiroisoxazoline Natural Product, Employing Optically Active Spiroisoxazoline Derivative. , 2006 .

[34]  H. Tomoda,et al.  Total Synthesis, Structural Revision, and Biological Evaluation of Calafianin, a Marine Spiroisoxazoline from the Sponge, Aplysina gerardogreeni , 2006 .

[35]  J. J. Harburn,et al.  Efficient synthesis of tyrosine-derived marine sponge metabolites via acylation of amines with a coumarin. , 2005, The Journal of organic chemistry.

[36]  T. Molinski,et al.  Stereochemical heterogeneity in Verongid sponge metabolites. Absolute stereochemistry of (+)-fistularin-3 and (+)-11-epi-fistularin-3 by microscale LCMS-Marfey's analysis. , 2005, Journal of natural products.

[37]  S. Nishiyama,et al.  Synthesis and structural revision of calafianin, a member of the spiroisoxazole family isolated from the marine sponge, Aplysina gerardogreeni , 2005 .

[38]  P. Parameswaran,et al.  New bromotyrosine alkaloids from the marine sponge Psammaplysilla purpurea , 2004 .

[39]  Y. Ishikawa,et al.  Electrochemical Synthesis of Spiroisoxazole Derivatives and Its Application to Natural Products , 2003 .

[40]  S. Nishiyama,et al.  A new ring-opening access to aeroplysinin-1, a secondary metabolite of Verongia aerophoba , 2003 .

[41]  M. Jaspars,et al.  Purealidin S and purpuramine J, bromotyrosine alkaloids from the Fijian marine sponge Druinella sp. , 2002, Journal of natural products.

[42]  E. Park,et al.  Cytotoxic anticancer candidates from natural resources. , 2002, Current medicinal chemistry. Anti-cancer agents.

[43]  S. Kumari,et al.  Natural products of plant origin as anticancer agents. , 2001, Drug news & perspectives.

[44]  J. J. Harburn,et al.  Approaches to the synthesis of some tyrosine-derived marine sponge metabolites: synthesis of verongamine and purealidin N. , 2001, The Journal of organic chemistry.

[45]  J. Malmstrøm,et al.  Calafianin, a bromotyrosine derivative from the marine sponge Aplysina gerardogreeni. , 2000, Journal of natural products.

[46]  F. Arvelo,et al.  11-Deoxyfistularin-3, a new cytotoxic metabolite from the caribbean sponge Aplysina fistularis insularis. , 1999, Journal of natural products.

[47]  M. Hamann,et al.  Bromotyrosine-derived metabolites from the spongeAiolochroia crassa , 1999 .

[48]  Rao,et al.  Novel bromine-containing constituents of the sponge psammaplysilla purpurea1 , 1999, Journal of natural products.

[49]  Magno,et al.  Chemistry of verongida sponges. 9.1 secondary metabolite composition of the caribbean sponge aplysina cauliformis , 1999, Journal of natural products.

[50]  Jimin Wang,et al.  Syntheses of the Marine Metabolites Verongamine (Va), Hemibastadin-2 (VII), and Aerothionin (X) Using the Cyano Ylide Coupling Methodology. , 1998 .

[51]  Rao,et al.  A new dibromotyrosine-derived metabolite from the sponge psammaplysilla purpurea1 , 1998, Journal of natural products.

[52]  Jianji Wang,et al.  Syntheses of the Marine Metabolites Verongamine, Hemibastadin-2, and Aerothionin Using the Cyano Ylide Coupling Methodology , 1998 .

[53]  O. Hoshino,et al.  Asymmetric Oxidative Cyclization of o-Phenolic Oxime-Esters: First Synthesis of Enantiomerically Enriched Spiroisoxazoline Methyl Esters. , 1997, The Journal of organic chemistry.

[54]  M. Kelly-Borges,et al.  Psammaplysin F, a new bromotyrosine derivative from a sponge, Aplysinella sp. , 1997, Journal of natural products.

[55]  H. Hirota,et al.  Ceratinamides A and B: New Antifouling Dibromotyrosine Derivatives from the Marine Sponge Pseudoceratina purpurea , 1996 .

[56]  Takuma Sasaki,et al.  Purealidins A-R, New Bromotyrosine Alkaloids from an Okinawan Marine Sponge Psammaplysilla purea , 1995 .

[57]  M. Tsuda,et al.  Lipopurealins D and E and Purealidin H, New Bromotyrosine Alkaloids from the Okinawan Marine Sponge Psammaplysilla purea , 1995 .

[58]  M. Kelly-Borges,et al.  Three bromotyrosine derivatives, one terminating in an unprecedented diketocyclopentenylidene enamine , 1993 .

[59]  I. Piña,et al.  The structures of aplysinamisines I, II, and III; new bromotyrosine-derived alkaloids from the Caribbean sponge Aplysina cauliformis. , 1993, Journal of natural products.

[60]  M. Tsuda,et al.  Purealidins E-G, New Bromotyrosine Alkaloids from the Okinawan Marine Sponge Psammaplysilla purea , 1992 .

[61]  A. Rodríguez,et al.  11-oxoaerothionin: a cytotoxic antitumor bromotyrosine-derived alkaloid from the Caribbean marine sponge Aplysina lacunosa. , 1992, Journal of natural products.

[62]  C. Ireland,et al.  Psammaplysin C: a new cytotoxic dibromotyrosine-derived metabolite from the marine sponge Druinella (= Psammaplysilla) purpurea. , 1992, Journal of natural products.

[63]  S. Gunasekera,et al.  Fistularin 3 and 11-ketofistularin 3. Feline leukemia virus active bromotyrosine metabolites from the marine sponge Aplysina archeri. , 1992, Journal of natural products.

[64]  M. Kernan,et al.  Chemistry of Sponges, VII. 11,19-Dideoxyfistularin 3 and 11-Hydroxyaerothionin, Bromotyrosine Derivatives from Pseudoceratina durissima , 1990 .

[65]  S. Nishiyama,et al.  Total Syntheses of (±)-Aerothionin, (±)-Homoaerothionin, and (±)-Aerophobin-1 , 1985 .

[66]  G. A. Gray,et al.  Structure of the psammaplysins , 1985 .

[67]  A. R. Forrester,et al.  Intramolecular Cyclisation of Phenolic Oximes, III.A Synthesis of cis-cis-Aerothionin , 1978 .

[68]  S. Dutta.  Natural sources as potential anti-cancer agents: A review , 2015 .

[69]  P. Govind.  MALNUTRITION LEADING TO CANCER BY SOME ENVIRONMENTAL HAZARDS , 2010 .

[70]  S. Nishiyama,et al.  Total syntheses of (±)-aerothionin and (±)-homoaerothionin , 1983 .

[71]  F. Schmitz,et al.  Marine natural products: fistularin-1, -2 and -3 from the sponge Aplysina fistularis forma fulva , 1979 .

[72]  E. Fattorusso,et al.  Aerothionin and homoaerothionin: two tetrabromo spirocyclohexadienylisoxazoles from Verongia sponges , 1972 .

[73]  E. Fattorusso,et al.  Aerothionin, a tetrabromo-compound from Aplysina aerophoba and Verongia thiona , 1970 .