Energy harvesting from a bio cell

This work shows experimentally how electrical energy can be harvested directly from cell membrane potential and used to power a wireless communication. The experiment is performed by exploiting the membrane potential of Xenopus oocytes taken from female frogs. Electrical potential energy of the membrane is transferred to a capacitor connected to the cell via a proper electrical circuit. Once the capacitor has reached the planned amount of energy, the circuit is disconnected from the cell and the stored energy is used to power a radio frequency communication that carries bio-sensed information to a distanced receiving circuit. Our result shows that electrical energy can be harvested directly from biological cells and used for a number of purposes, including wireless communication of sensed biological quantities to a remote receiving hub.

[1]  G. Volpe,et al.  Active Particles in Complex and Crowded Environments , 2016, 1602.00081.

[2]  Metin Sitti,et al.  Miniature devices: Voyage of the microrobots , 2009, Nature.

[3]  M. D’Adamo,et al.  Expression and function of a CP339,818-sensitive K⁺ current in a subpopulation of putative nociceptive neurons from adult mouse trigeminal ganglia. , 2015, Journal of neurophysiology.

[4]  Metin Sitti,et al.  Mobile microrobots for bioengineering applications. , 2017, Lab on a chip.

[5]  Hiroki Morimura,et al.  Ultra-low-power circuit techniques for mm-size wireless sensor nodes with energy harvesting , 2014, IEICE Electron. Express.

[6]  Robert Simmons,et al.  Sense and sensibility , 2001, Nature.

[7]  Luca Gammaitoni,et al.  Towards zero-power ICT , 2015, Nanotechnology.

[8]  I. Plesner,et al.  The steady-state kinetic mechanism of ATP hydrolysis catalyzed by membrane-bound (Na+ + K+)-ATPase from ox brain. I. Substrate identity. , 1981, Biochimica et biophysica acta.

[9]  Metin Sitti,et al.  Bio-hybrid cell-based actuators for microsystems. , 2014, Small.

[10]  G. Leier,et al.  Endogenous transport systems in the Xenopus laevis oocyte plasma membrane. , 2010, Methods.

[11]  A. Chandrakasan,et al.  Energy extraction from the biologic battery in the inner ear , 2012, Nature Biotechnology.

[12]  Joseph Wang,et al.  Rocket Science at the Nanoscale. , 2016, ACS nano.

[13]  H. G. Ferreira,et al.  Determination of ionic permeability coefficients of the plasma membrane of Xenopus laevis oocytes under voltage clamp. , 1989, The Journal of physiology.

[14]  T. Clausen Na+-K+ pump regulation and skeletal muscle contractility. , 2003, Physiological reviews.

[15]  J. Davies,et al.  Molecular Biology of the Cell , 1983, Bristol Medico-Chirurgical Journal.

[16]  R. Miledi,et al.  Cholinergic and catecholaminergic receptors in the Xenopus oocyte membrane , 1982, The Journal of physiology.

[17]  Eric Diller,et al.  Biomedical Applications of Untethered Mobile Milli/Microrobots , 2015, Proceedings of the IEEE.

[18]  Ioannis K. Kaliakatsos,et al.  Microrobots for minimally invasive medicine. , 2010, Annual review of biomedical engineering.

[19]  Anthony P F Turner,et al.  Biosensors: sense and sensibility. , 2013, Chemical Society reviews.

[20]  Christian Piguet,et al.  Low-Power Electronics Design , 2004 .

[21]  P V Hegarty,et al.  Sarcomere length and fibre diameter distributions in four different mouse skeletal muscles. , 1971, Journal of anatomy.