Genetic Algorithms and Information Accumulation during the Evolution of Gene Regulation

• Cordero OX, Snel B, Hogeweg P.(2008), Coevolution of gene families in prokaryotes. Genome Res. (epub ahead of print) • Grieneisen V.A., Xu J., Maree A.F., Hogeweg P. & Scheres B. ( 2007), Auxin transport is sufficient to generate a maximum and gradient guiding root growth. Nature, 449: 1008-1013. • Van Hoek M.J. & Hogeweg P. (2007b), The role of mutational dynamics in genome shrinkage. Mol. Biol. Evol., 24: 2485-2494 • Van Hoek M. & Hogeweg P. (2007a), The effect of stochasticity on the lac operon: an evolutionary perspective. PLoS. Comput. Biol., 3: e111. • Takeuchi N. & Hogeweg P. (2007b), The Role of Complex Formation and Deleterious Mutations for the Stability of RNA-Like Replicator Systems. J. Mol. Evol., 65: 668-686. • Takeuchi N. & Hogeweg P. (2007a), Error-threshold exists in fitness landscapes with lethal mutants. BMC. Evol. Biol., 7: 15 • Grieneisen V.A., Xu J., Maree A.F., Hogeweg P. & Scheres B. ( 2007), Auxin transport is sufficient to generate a maximum and gradient guiding root growth. Nature, 449: 1008-1013. • Hogeweg P. (2007), From population dynamics to ecoinformatics: Ecosystems as multilevel information processing systems. Ecological Informatics, 2: 103-111. • Crombach A. & Hogeweg P. (2007), Chromosome rearrangements and the evolution of genome structuring and adaptability. Mol. Biol. Evol., 24: 1130-1139. • Cordero O.X. & Hogeweg P. (2007), Large changes in regulome size herald the main prokaryotic lineages. Trends Genet., 23: 488-493 • Van Hoek M.J. & Hogeweg P. (2006), In silico evolved lac operons exhibit bistability for artificial inducers, but not for lactose. Biophys. J., 91: 2833-2843 • Van Der Post D.J. & Hogeweg P. (2006), Resource distributions and diet development by trial-and-error learning. Behav. Ecol. Sociobiol., 61: 65-80 • Merks R.M., Hoekstra A.G., Kaandorp J., Sloot P.M.A. & Hogeweg P. 2006) Problem-solving environments for biological morphogenesis. Computing in Science and Engineering, 8: 61-72. • Kafer J., Hogeweg P. & Marée A.F. (2006),

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